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Antigen Express awarded Therapeutic Discovery Project grants for cancer vaccine development

Generex Biotechnology Corporationannounced today that its wholly-owned immunotherapeutics subsidiary, Antigen Express, Inc. has been awarded two Therapeutic Discovery Project grants, totaling $488,958.50, by the United States Internal Revenue Service (IRS) and the Department of Health and Human Services (HHS) pursuant to the Patient Protection and Affordable Care Act of 2010.

10 Nov 2010

Simple test and an MRI predicts future Alzheimer’s disease

Until now is has been believed that Alzheimer’s disease and other forms of dementia could be diagnosed only when symptoms appear which almost always means when patients are in their 70s or 80s. Now the latest research shows that some brain lesions are characteristic of Alzheimer’s disease and can be detected in the brains of healthy people in their 40s. Along with this a simple mental skills test may be able to detect the problem many years sooner than previously thought.

10 Nov 2010

Statins benefit ‘at risk’ patients but are underused: Study

A look at some of the large clinical trials and studies has shown that thousands of deaths could be prevented a year if people at risk of heart attack or stroke are prescribed high doses of statins. The review involves data from 170,000 patients in 26 randomized trials. The paper is published in the journal The Lancet.

10 Nov 2010

Lung cancer in smokers versus non-smokers shows different genetic mutations

A group of scientists at B.C. Cancer Agency have found that lung cancers in smokers have different genetic mutations and look different than lung cancer in non-smokers. According to senior scientist at the BC Cancer Agency Research Centre Wan Lam, this finding is significant because it means that from now on, research, treatments and diagnostics should be tailored to the distinct genetic variations in the different lung cancers instead of expecting that a one-size fits all approach will work. He said, “At the current time, treatment does not distinguish between these different types. The subtypes are all grouped together. But with this work, we are beginning to tease out the subtypes.” The study was presented Tuesday at a conference in Philadelphia of the American Association of Cancer Research.

10 Nov 2010

Obese teens become obese adults

A new report shows that obese adolescent Americans tend to carry their extra weight into adulthood. The nationally representative study of American youth showed that one in 12 teenagers became severely obese as they entered adulthood with some 100 pounds above their ideal weight. And nearly half the girls and more than a third of the boys who are obese as teenagers grew up to be obese adults with a high risk of developing heart disease, diabetes and certain types of cancers.

10 Nov 2010

Researchers identify molecular cascade that drives process of reconnection in adult brain after stroke

A stroke wreaks havoc in the brain, destroying its cells and the connections between them. Depending on its severity and location, a stroke can impact someone's life forever, affecting motor activity, speech, memories, and more.

10 Nov 2010

Omeros identifies orphan GPCR compound that potentiates tumor-killing activity of doxorubicin

Omeros Corporation, a biopharmaceutical company committed to discovering, developing and commercializing products focused on inflammation and disorders of the central nervous system, today announced that a compound identified by the Company as an antagonist of GPR87, an orphan GPCR recently unlocked for drug development by Omeros and linked to squamous cell carcinoma, potentiates the tumor-killing activity of doxorubicin (Adriamycin), a widely used chemotherapeutic agent.

10 Nov 2010

Study shows dogs attack children's face, eyes

As dog bites become an increasingly major public health concern, a new study shows that unsupervised children are most at risk for bites, that the culprits are usually family pets and if they bite once, they will bite again with the second attack often more brutal than the first.

10 Nov 2010

Receptive music therapy associated with reduced depressive symptoms

A Swedish study that appears in the current issue of Psychotherapy and Psychosomatics applies music therapy to the treatment of depression.

10 Nov 2010

Study finds no association between working in wafer fabrication cleanrooms, cancer mortality

An exhaustive, five-year epidemiological study conducted by researchers from Vanderbilt University covering more than 100,000 semiconductor industry workers found no association between overall cancer mortality and working in wafer fabrication cleanrooms, the Semiconductor Industry Association reported today.

10 Nov 2010

Hospitals need to work more to prevent heart attack deaths: Study

Door-to-balloon time has dropped dramatically as hospitals rush heart attack patients into treatment, but a five-year study released Monday shows quicker hospital care has not saved more lives.

10 Nov 2010

Covidien analysis finds lower incidence of GI adverse events with topical NSAIDs versus oral

Covidien, a leading global provider of healthcare products, announced the results of an analysis that will be presented at the American College of Rheumatology's Annual Scientific Meeting. A pooled analysis of safety data suggests that patients with knee osteoarthritis (OA) receiving the topical PENNSAID® (diclofenac sodium topical solution) 1.5% w/w had significantly fewer gastrointestinal (GI)-related adverse events than those receiving an oral non-steroidal anti-inflammatory drug (NSAID).

10 Nov 2010

EuroNanoMed funds 8 projects with €8 Million for transnational research projects in nanomedicine

EuroNanoMed, a European funding initiative under the ERA-Net scheme of the European Commission aimed at advancing transnational research in Nanomedicine, announced today the projects that will be funded following its 2nd joint transnational call for collaborative research projects. Eight projects, involving 46 partners from 10 countries will be funded with €8 Million provided by EuroNanoMed partners. The research projects were chosen from 33 applications involving 178 applicant groups from 19 EU member and associated states/regions.

10 Nov 2010

Low levels of growth hormone may contribute to growth defects in cystic fibrosis

A new study using a pig model of cystic fibrosis (CF) suggests that low levels of a growth promoting hormone at or before birth may contribute to growth defects in patients with CF.

10 Nov 2010

Fibroblast growth factor-2 stimulates periodontal regeneration: Study

It is well known that oral infection progressively destroys periodontal tissues and is the leading cause of tooth loss in adults. A major goal of periodontal treatment is regeneration of the tissues lost to periodontitis. Unfortunately, most current therapies cannot predictably promote repair of tooth-supporting defects. A variety of regenerative approaches have been used clinically using bone grafts and guiding tissue membranes with limited success.

10 Nov 2010

Nine research projects awarded access to PRACE Research Infrastructure

Nine research projects, two from Germany, two from Spain and one each from France, Hungary, the Netherlands, Portugal and the UK, have been awarded access to the PRACE Research Infrastructure. In total 362.8 Million compute core hours were granted for the JUGENE, IBM BlueGene/P, hosted by the Gauss-Centre for Supercomputing member site in Jülich, Germany, which is the first Petascale HPC system available to researchers through PRACE.

10 Nov 2010

Long-term use of statins unlikely to substantially increase overall cancer risk: Study

Researchers have further established that long-term use of statins is unlikely to substantially increase or decrease overall cancer risk, according to study results presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10, 2010, in Philadelphia.

10 Nov 2010

Article shows link between maternal cigarette smoking during pregnancy, SIDS

The link between maternal cigarette smoking during pregnancy and Sudden Infant Death Syndrome may relate to the negative effects of nicotine on the development of brain centers that regulate breathing, according to an article in the recent issue of Pediatric Allergy, Immunology, and Pulmonology, a peer-reviewed journal published by Mary Ann Liebert, Inc.

10 Nov 2010

Preclinical data from Idera's autoimmune and inflammatory disease program presented at 74th ACR

Idera Pharmaceuticals, Inc. today announced two presentations of preclinical data from its autoimmune and inflammatory disease program at the 74th Annual Scientific Meeting of the American College of Rheumatology (ACR) in Atlanta, Georgia. One presentation is entitled "IMO-3100, a Toll-like Receptor (TLR) Antagonist, Suppresses TLR7- and TLR9-mediated Immune Responses in Non-human Primates" (#856).

10 Nov 2010

Jefferson awarded $2.6M grant for study on cognitive decline in older African Americans with MCI

Researchers in the Departments of Psychiatry and Neurology at Jefferson Medical College of Thomas Jefferson University were recently awarded a $2.6 million grant from The National Institute of Health to study whether increasing participation in cognitive, physical and/or social activities prevents cognitive decline in older African Americans with Mild Cognitive Impairment (MCI).

10 Nov 2010

Medical Research News

Antigen Express awarded Therapeutic Discovery Project grants for cancer vaccine development

Simple test and an MRI predicts future Alzheimer’s disease

Statins benefit ‘at risk’ patients but are underused: Study

Lung cancer in smokers versus non-smokers shows different genetic mutations

Obese teens become obese adults

Researchers identify molecular cascade that drives process of reconnection in adult brain after stroke

Omeros identifies orphan GPCR compound that potentiates tumor-killing activity of doxorubicin

Study shows dogs attack children's face, eyes

Receptive music therapy associated with reduced depressive symptoms

Study finds no association between working in wafer fabrication cleanrooms, cancer mortality

Hospitals need to work more to prevent heart attack deaths: Study

Covidien analysis finds lower incidence of GI adverse events with topical NSAIDs versus oral

EuroNanoMed funds 8 projects with €8 Million for transnational research projects in nanomedicine

Low levels of growth hormone may contribute to growth defects in cystic fibrosis

Fibroblast growth factor-2 stimulates periodontal regeneration: Study

Nine research projects awarded access to PRACE Research Infrastructure

Long-term use of statins unlikely to substantially increase overall cancer risk: Study

Article shows link between maternal cigarette smoking during pregnancy, SIDS

Preclinical data from Idera's autoimmune and inflammatory disease program presented at 74th ACR

Jefferson awarded $2.6M grant for study on cognitive decline in older African Americans with MCI

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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