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Researchers identify novel mechanism in control of cell motility

A team of scientists at the Institut de recherches cliniques de Montr-al (IRCM) led by Dr. Jean-Fran-ois C-t-, Director of the Cytoskeletal Organization and Cell Migration research unit, identified a novel molecular mechanism in the control of cell motility. Their findings were published online today in Current Biology, a journal from the Cell Press group. This scientific breakthrough could eventually lead to the development of new cancer-treating drugs that could block the spread of tumours (metastasis).

29 Oct 2010

Number of beta cells remains static after age 30: Research

Beta cells, which make insulin in the human body, do not replicate after the age of 30, indicating that clinicians may be closer to better treating diabetes.

29 Oct 2010

New findings on Th17 cells pave way for human cancer treatment protocol

A recently identified immune cell that directs other cells to fight infection plays a critical role in regulating the immune system in both health and disease. Researchers from the University of Pennsylvania School of Medicine have discovered how a stimulatory molecule and a protein found on the membrane of another immune cell make T helper 17 cells multi-taskers of sorts. Th17 cells protect the body against infection and cancer, but are also culprits in some autoimmune diseases and out-of-control, cancerous cell growth.

29 Oct 2010

Low household income associated with chronic migraine

New data presented today at The 2010 European Headache and Migraine Trust International Congress (EHMTIC) shows that persons with chronic migraine (headache on greater than or equal to 15 days per month) are much more likely to have annual household incomes below $30,000 than those with episodic migraine (headache on < 15 days per month).

29 Oct 2010

New approach for early diagnosis of pancreatic cancer

Pancreatic tumors are one of the most lethal cancers, with fewer than five percent of patients surviving five years after diagnosis. But a new study that peers deeply into the genetics of pancreatic cancer presents a bit of good news an opportunity for early diagnosis. In contrast to earlier predictions, many pancreatic tumors are, in fact, slow growing, taking nearly 20 years to become lethal after the first genetic perturbations appear.

29 Oct 2010

Scientists develop new method to analyze early detection of virus

The virus, called enterovirus 71, is closely related to poliovirus, and was first detected in California in the 1960s. Since then the virus has spread across Asia, affecting mostly children and some adults. Serious cases of the disease can include neurological disorders such as meningitis, paralysis and encephalitis.

29 Oct 2010

Researchers develop morpholino oligonucleotides that can turn off specific genes

Researchers at North Carolina State University have found a way to "cage" genetic off switches in such a way that they can be activated when exposed to UV light. Their technology gives scientists a more precise way to control and study gene function in localized areas of developing organisms.

29 Oct 2010

Research on sheep population could help explain variation in vaccine protection

Strong immunity may play a key role in determining long life, but may do so at the expense of reduced fertility, a Princeton University study has concluded.

29 Oct 2010

Study finds site of tumor impacts disease stage in head and neck cancer

Developing a molecular fingerprint for head and neck cancer tumors could help improve diagnosis and treatment for this deadly and often-times disfiguring form of cancer, according to researchers at Henry Ford Hospital in Detroit.

29 Oct 2010

Scientists identify potential new treatment for Nipah and Hendra viruses

Scientists at Weill Cornell Medical College have identified a potential new treatment for the Nipah and Hendra viruses, two lethal and emerging viruses for which there is currently no treatment or vaccine available. The approach could also lead to new therapies for measles, mumps and the flu. The new research appears in today's edition of the prestigious journal Public Library of Science (PLoS) Pathogens.

29 Oct 2010

Low birth weight linked to poor growth in children with CKD

The lower the birth weight, the greater the chance of poor growth rate in children with chronic kidney disease (CKD), according to a new study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

29 Oct 2010

Long hours and nights on call lead to surgeon distress

Just as with everyone else perhaps, the more hours surgeons work, and the more nights they spend on call each week, the more likely they are to face burn-out, depression, dissatisfaction with their careers and serious work-home conflicts, according to a major new study led by Johns Hopkins and Mayo Clinic researchers.

29 Oct 2010

Chillies for diabetes: Study

Researchers from Tasmania, Australia are recruiting volunteers in a study to explore if eating chillies can help control lifestyle-related diabetes. At present they need 35 people with type 2 diabetes or glucose intolerance.

28 Oct 2010

Common psychiatric drugs could slow dementia

Researchers say commonly used psychiatric drugs could be effective in slowing the progression of certain types of dementia. Dr John Kwok and colleagues from Neuroscience Research Australia have discovered a mutant gene that causes abnormal proteins build up in the brains of people with frontotemporal dementia, a disease that affects people in their 50s and 60s.

28 Oct 2010

Study examines heavy alcohol consumption

Problem drinkers in the general population may reduce the amount of alcohol they consume over a period of years but not to the level of the average adult, according to a new study in the November issue of the Journal of Studies on Alcohol and Drugs.

28 Oct 2010

New nationwide initiative to conduct research on human immune system

A new nationwide research initiative has been launched to define changes in the human immune system's response to infection and vaccination using human rather than animal models, which could lead to better vaccines and other treatments. Baylor Research Institute (BRI), along with five other U.S.-based Human Immune Phenotyping Centers, will receive a total of $100 million over five years to conduct the research.

28 Oct 2010

Researchers investigate relation between cortical thickness and nicotine dependence

Is there a relation between the structure of specific regions of the brain and nicotine dependence? This is the question researchers of the Charité - Universitätsmedizin Berlin and of the Physikalisch-Technische Bundesanstalt (PTB), the German National Metrology Institute, have been investigating lately. The results of these investigations extend and specify those of preceding studies: A specific region of the cerebral cortex of smokers is thinner than that of people who have never smoked in their lives.

28 Oct 2010

MRI awarded $31M NIH contract to provide chemistry support for National Toxicology Program

Midwest Research Institute (MRI), one of the nation's leading independent research organizations, with more than 65-years of experience in scientific research, has been awarded a $31 million contract from the National Institute of Environmental Health Sciences. Under the 5-year contract, MRI scientists will provide chemical procurement, handling, and analytical chemistry services requested by the National Toxicology Program (NTP) for toxicology studies in progress throughout the U.S.

28 Oct 2010

Outcomes detects over one million drug therapy problems through Targeted Intervention Program

Outcomes Pharmaceutical Health Care® has announced it has detected over one million drug therapy problems through its Targeted Intervention Program (TIP®).

28 Oct 2010

Immune system may play a role in cancer therapies: Study

The immune system may play a critical role in ensuring the success of certain types of cancer therapies, according to a new study by researchers at the Stanford University School of Medicine. The research showed treatments that disable cancer-promoting genes called oncogenes are much more successful in eradicating tumors in the presence of a signaling molecule secreted by kind of immune cell called a T helper cell.

28 Oct 2010