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Racial and ethnic groups less likely to receive kidney transplants than others

Not all racial and ethnic groups have equal access to kidney transplantation, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology. The results indicate that the reasons for these disparities are varied and that more focused efforts are needed to address them.

3 Mar 2011

Feet first? Old mitochondria might be responsible for neuropathy in the extremities

The burning, tingling pain of neuropathy may affect feet and hands before other body parts because the powerhouses of nerve cells that supply the extremities age and become dysfunctional as they complete the long journey to these areas, Johns Hopkins scientists suggest in a new study. The finding may eventually lead to new ways to fight neuropathy, a condition that often accompanies other diseases including HIV/AIDS, diabetes and circulatory disorders.

3 Mar 2011

Genetics and cancer research

The 20th century was dominated by breakthroughs in physics and chemistry, but the 21st century will belong to genetics and biotechnology. Cancer research is just one area among many that is being transformed by the sequencing of the human genome. This was one of the topics discussed in our recent panel with leading cancer researchers, part of our Breakthroughs: Cancer series.

3 Mar 2011

New study: Talk Test is a useful indicator of VT in trained athletes

The "Talk Test" provides a simple and reliable indicator of the proper training intensity for runners, suggests a report in the March issue of The Journal of Strength and Conditioning Research, official research journal of the National Strength and Conditioning Association. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

3 Mar 2011

New insight: p53 protein controls molecular crossroads in glucose metabolic pathway

The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins.

3 Mar 2011

New discovery in glioma-associated metabolic changes

Metabolon, Inc., the leader in metabolomics, biomarker discovery and analysis, announces the publication of "Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome", in The Proceedings of the National Academy of Sciences.

3 Mar 2011

Novel study deepens understanding of how chromosome replication works

A novel study from the Swedish medical university Karolinska Institutet has deepened the understanding of how chromosome replication, one of life's most fundamental processes, works.

3 Mar 2011

New research provides insight into link between sunlight, vitamin D3, MS risk and severity

New research into the neurodegenerative disease, Multiple Sclerosis offers new insight into the link between sunlight, vitamin D3, and MS risk and severity.

3 Mar 2011

Study reveals expansion of NK cells after acute infection

The natural killer cells of our immune defense are activated for an extended period after the acute infection, which challenges the prevailing view that the elevation and activation of cells quickly pass.

3 Mar 2011

New research: Weight discrimination may impact physical health

The discrimination that obese people feel, whether it is poor service at a restaurant or being treated differently in the workplace, may have a direct impact on their physical health, according to new research from Purdue University.

3 Mar 2011

Scientists find reprogramming-associated mutations in hiPSCs

Ordinary human cells reprogrammed as induced pluripotent stem cells may ultimately revolutionize personalized medicine by creating new and diverse therapies unique to individual patients.

3 Mar 2011

Groundbreaking discovery in lymphoma research

BC Cancer Agency scientists have discovered that a single gene, CIITA, is implicated in almost 40 per cent of primary mediastinal B-cell lymphomas and 15 per cent of all Hodgkin lymphoma cases.

3 Mar 2011

New study examines boxing injuries among children and adolescents from 1990 to 2008

The risk and nature of injury in the sport of boxing has generated a great deal of controversy in the medical community, especially in relation to youth boxing. A new study, conducted by researchers in the Center for Injury Research and Policy of The Research Institute at Nationwide Children's Hospital, examined boxing injuries among participants 6 years of age and older from 1990 to 2008.

3 Mar 2011

Early diagnosis of juvenile idiopathic arthritis critical to avoid disability, deformity

While lab tests and imaging can sometimes help diagnose juvenile idiopathic arthritis (JIA), a physical examination and thorough patient history are the most valuable tools in identifying this disease. According to a new literature review from the Journal of the American Academy of Orthopaedic Surgeons (JAAOS), the rate of false positives in laboratory evaluations and imaging studies meant to screen for juvenile arthritis makes their value limited.

3 Mar 2011

Birth of healthy child does not resolve depression and anxiety in women who miscarry

The depression and anxiety experienced by many women after a miscarriage can continue for years, even after the birth of a healthy child, according to a study led by University of Rochester Medical Center researchers and published online today by the British Journal of Psychiatry.

3 Mar 2011

New study: Significant deterioration in semen quality during last 10 years in Finland

A new study published in the International Journal of Andrology reveals that semen quality has significantly deteriorated during the last ten years in Finland, a country that previously was a region with high sperm counts.

3 Mar 2011

U-M scientists identify potential target to treat aggressive prostate cancer

Researchers at the University of Michigan Comprehensive Cancer Center have identified a potential target to treat an aggressive type of prostate cancer. The target, a gene called SPINK1, could be to prostate cancer what HER2 has become for breast cancer.

3 Mar 2011

ITI, Takeda collaborate to develop and commercialize PDE1 inhibitors for schizophrenia

Intra-Cellular Therapies, Inc. ("ITI") and Takeda Pharmaceutical Company Limited, today announced that they have entered into an exclusive collaboration to develop and commercialize selective phosphodiesterase type 1 (PDE1) inhibitors, discovered by ITI, for the treatment of cognitive impairment associated with schizophrenia. This agreement is targeted worldwide, but ITI has retained the option to co-promote with Takeda in the United States.

3 Mar 2011

Scientists provide new insight into mechanisms controlling programmed cell death pathways

Work led by St. Jude Children's Research Hospital investigators provides fresh insight into mechanisms controlling programmed cell death pathways and offers new targets in the fight against cancer and virus-infected cells

3 Mar 2011

Women smokers over 50 at increased risk of breast cancer

Compared to women who had never smoked, breast cancer risk increased by nine percent among former smokers and by 16 percent among current smokers according to research by Karen Margolis, MD, a senior clinical investigator with the HealthPartners Research Foundation and her collaborators in a study that was published today in the British Medical Journal.

3 Mar 2011

Medical Research News

Racial and ethnic groups less likely to receive kidney transplants than others

Feet first? Old mitochondria might be responsible for neuropathy in the extremities

Genetics and cancer research

New study: Talk Test is a useful indicator of VT in trained athletes

New insight: p53 protein controls molecular crossroads in glucose metabolic pathway

New discovery in glioma-associated metabolic changes

Novel study deepens understanding of how chromosome replication works

New research provides insight into link between sunlight, vitamin D3, MS risk and severity

Study reveals expansion of NK cells after acute infection

New research: Weight discrimination may impact physical health

Scientists find reprogramming-associated mutations in hiPSCs

Groundbreaking discovery in lymphoma research

New study examines boxing injuries among children and adolescents from 1990 to 2008

Early diagnosis of juvenile idiopathic arthritis critical to avoid disability, deformity

Birth of healthy child does not resolve depression and anxiety in women who miscarry

New study: Significant deterioration in semen quality during last 10 years in Finland

U-M scientists identify potential target to treat aggressive prostate cancer

ITI, Takeda collaborate to develop and commercialize PDE1 inhibitors for schizophrenia

Scientists provide new insight into mechanisms controlling programmed cell death pathways

Women smokers over 50 at increased risk of breast cancer

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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