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World's largest data base on protein motions

After four years of conducting intensive calculations in the supercomputer MareNostrum at the Barcelona Supercomputing Center, scientists headed by Modesto Orozco at the Institute for Research in Biomedicine (IRB Barcelona) have presented the world's largest data base on protein motions. Called MoDEL, this new database holds more than 1,700 proteins and is partially accessible through Internet to researchers worldwide. MoDEL has been developed to study the basic biology of proteins and to accelerate and facilitate the design of new pharmaceutical agents.

11 Nov 2010

Neural learning appears to be independent of conscious visual processing

A team of researchers from the University of Minnesota's College of Liberal Arts and College of Science and Engineering have found that an early part of the brain's visual system rewires itself when people are trained to perceive patterns, and have shown for the first time that this neural learning appears to be independent of higher order conscious visual processing.

11 Nov 2010

Study: Cognitive symptoms of depression cannot be discarded as risk factors for heart disease progression

Cognitive symptoms of depression cannot be simply discarded as risk factors for heart disease progression. When using a structured diagnostic interview, both somatic and cognitive symptoms of depression are associated with adverse cardiac outcome after adjusting for potential confounders.

11 Nov 2010

Halpin Foundation-ASN grant advances research in membranous nephropathy

The Halpin Foundation and the American Society of Nephrology (ASN) proudly highlight the research advances in membranous nephropathy made possible by The Halpin Foundation-ASN Research Grant, created to help young faculty develop independent research careers. This award provides recipients transition funding toward successful application for an NIH RO1 grant.

11 Nov 2010

Neuron subtypes control level of fear output from amygdala

The eerie music in the movie theater swells; the roller coaster crests and begins its descent; something goes bump in the night. Suddenly, you're scared: your heart thumps, your stomach clenches, your throat tightens, your muscles freeze you in place. But fear doesn't come from your heart, your stomach, your throat, or your muscles. Fear begins in your brain, and it is there specifically in an almond shaped structure called the amygdala that it is controlled, processed, and let out of the gate to kick off the rest of the fear response.

11 Nov 2010

TFAH's new report on flu finds higher hospitalization rates among African Americans

H1N1 flu hospitalization rates for African-Americans, Hispanics, and American Indian/Alaska Natives were nearly two to one higher than rates for Whites during the 2009-2010 flu season, according to a new report, Fighting Flu Fatigue, from the Trust for America's Health (TFAH). At the same time, both H1N1 and seasonal flu vaccination rates were lower for African Americans and Hispanics than for Whites.

11 Nov 2010

Most drug and biological product makers meet postmarketing requirements and commitments

Most makers of approved drug and biological products are meeting their regulatory obligations and meeting targets for postmarketing studies/clinical trials in a timely manner, according to a study released today by the U.S. Food and Drug Administration (FDA).

11 Nov 2010

FSU and Denver VA Medical Center awarded $17M grant to establish Military Suicide Research Consortium

American soldiers are taking their own lives in the largest numbers since the military began keeping records, and the Department of Defense has enlisted the help of The Florida State University in waging the war against suicide.

11 Nov 2010

New findings suggest serotonin may have anti-diabetic property

New findings by researchers at UT Southwestern Medical Center suggest that serotonin a brain chemical known to help regulate emotion, mood and sleep might also have anti-diabetic properties.

11 Nov 2010

Portugal research groups awarded Gates Foundation grants

Two research groups in Portugal are to receive Grand Challenges Exploration Grants from the Bill & Melinda Gates Foundation. One of these research teams is led by Miguel Prud-ncio, at the Instituto de Medicina Molecular (IMM), and the other by Miguel Soares, at the Instituto Gulbenkian de Ci-ncia (IGC) together with Henrique Silveira, at the Instituto de Higiene e Medicina Tropical (IHMT).

11 Nov 2010

New approach to sneak nerve-protective drug erythropoietin into blood-brain barrier

Scientists are reporting development of a long-sought method with the potential for getting medication through a biological barrier that surrounds the brain, where it may limit the brain damage caused by stroke. Their approach for sneaking the nerve-protective drug erythropoietin into the brain is medicine's version of the Trojan Horse ploy straight out of ancient Greek legend.

11 Nov 2010

Researchers identify molecular cascade that drives sprouting in brain after stroke

A stroke wreaks havoc in the brain, destroying its cells and the connections between them. Depending on its severity and location, a stroke can impact someone's life forever, affecting motor activity, speech, memories, and more.

11 Nov 2010

Scientists identify new way to drive dendritic cells from blood monocytes

Dendritic cells, known to be the prime movers of the body's immune response, are still notoriously difficult to study in humans. Samples, which come primarily from bone marrow or lymphoid tissue, are simply too difficult to obtain. But new research at Rockefeller University has shown scientists a way to study "authentic" dendritic cells from mouse monocytes, which are abundant in the blood, a much more accessible source in humans.

11 Nov 2010

Cortex applauds Servier for intent to move High Impact AMPAKINE compound into Phase I clinical studies

Cortex Pharmaceuticals, Inc. announced that it had been notified by Les Laboratoires Servier ("Servier"), France's largest privately held pharmaceutical company, of their intent to move forward into Phase I clinical studies with the jointly-discovered High Impact AMPAKINE® compound S47445 (CX1632).

11 Nov 2010

Genetic constitution can influence changes in tumor growth: Study

The genes we possess not only determine the color of our eyes and hair and how our bodies grow, they might also influence the changes that occur in tumors when we develop cancer.

11 Nov 2010

New discovery can develop diagnostic test to identify gene mutation in AML

Decoding the DNA of a woman who died of acute myeloid leukemia (AML) has led researchers at Washington University School of Medicine in St. Louis to a gene that they found to be commonly altered in many patients who died quickly of the disease.

11 Nov 2010

Study on zebrafish showcases neural basis of essential survival skill

A tiny, translucent juvenile zebrafish, on the hunt for even littler prey, has offered up a big insight into how a specific circuit of nerve cells functions in the brain. The technique used to illuminate this circuitry, and the fish model itself, provide one of the first insights into the way individual sets of neurons control a specific behavior.

11 Nov 2010

SuperGen discontinues clinical development of SGI-1776 PIM kinase drug candidate

SuperGen, Inc. today announced that it has discontinued clinical development of its phase 1 PIM kinase drug candidate, SGI-1776, while continuing development of the PIM inhibitor program.

11 Nov 2010

Infant foods must be protected against fumonisin toxin

An international team of scientists calls for protecting complementary food for infants in developing countries - especially those where corn is a staple food - against fumonisin, a toxin produced by fungi. Until now, physicians thought the growth retardation of children in those regions was to be blamed on the poor nutritional value of the complementary maize porridge they receive when breast milk is no longer sufficient. But toxins indeed are involved, the scientists report in the journal Molecular Nutrition and Food Research.

10 Nov 2010

Chocolates inhibit enzyme known to raise blood pressure

Numerous studies have shown that cocoa has a protective effect against cardiovascular diseases. The reason for this has now been uncovered by researchers at Linköping University in Sweden. When a group of volunteers devoured a good-sized piece of dark chocolate, it inhibited an enzyme in their bodies that is known to raise blood pressure.

10 Nov 2010

Medical Research News

World's largest data base on protein motions

Neural learning appears to be independent of conscious visual processing

Study: Cognitive symptoms of depression cannot be discarded as risk factors for heart disease progression

Halpin Foundation-ASN grant advances research in membranous nephropathy

Neuron subtypes control level of fear output from amygdala

TFAH's new report on flu finds higher hospitalization rates among African Americans

Most drug and biological product makers meet postmarketing requirements and commitments

FSU and Denver VA Medical Center awarded $17M grant to establish Military Suicide Research Consortium

New findings suggest serotonin may have anti-diabetic property

Portugal research groups awarded Gates Foundation grants

New approach to sneak nerve-protective drug erythropoietin into blood-brain barrier

Researchers identify molecular cascade that drives sprouting in brain after stroke

Scientists identify new way to drive dendritic cells from blood monocytes

Cortex applauds Servier for intent to move High Impact AMPAKINE compound into Phase I clinical studies

Genetic constitution can influence changes in tumor growth: Study

New discovery can develop diagnostic test to identify gene mutation in AML

Study on zebrafish showcases neural basis of essential survival skill

SuperGen discontinues clinical development of SGI-1776 PIM kinase drug candidate

Infant foods must be protected against fumonisin toxin

Chocolates inhibit enzyme known to raise blood pressure

Exploring the G:Box and for high-quality imaging

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

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