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Certain human leukemias can be treated by targeting stem-cell microRNAs: Research

Hematopoietic stem cells provide the body with a constant supply of blood cells, including the red blood cells that deliver oxygen and the white blood cells that make up the immune system. Hematopoietic-or blood-stem cells must also make more copies of themselves to ensure that they are present in adequate numbers to provide blood throughout a person's lifetime, which means they need to strike a delicate balance between self-renewal and development into mature blood-cell lineages. Perturb that balance, and the result can be diseases such as leukemia and anemia.

5 Aug 2010

Thinking of God reduces distress to anxiety-provoking mistakes: Study

Thinking about God may make you less upset about making errors, according to a new study published in Psychological Science, a journal of the Association for Psychological Science. The researchers measured brain waves for a particular kind of distress-response while participants made mistakes on a test. Those who had been prepared with religious thoughts had a less prominent response to mistakes than those who hadn't.

5 Aug 2010

Simmons Comprehensive Cancer Center at UT Southwestern attains National Cancer Institute designation

The Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center has attained National Cancer Institute (NCI) designation, an elite distinction held by only the top-tier cancer centers nationwide.

5 Aug 2010

Study links sea sponge genome sequence with first animals and cancer

The sponge, which was not recognized as an animal until the 19th century, is now the simplest and most ancient group of animals to have their genome sequenced. In a paper appearing in the August 5 issue of the journal Nature, a team of researchers led by Daniel Rokhsar of the University of California, Berkeley, and the Department of Energy's Joint Genome Institute (JGI), report the draft genome sequence of the sea sponge Amphimedon queenslandica and several insights the genome gives into the origins of both the first animals and cancer.

5 Aug 2010

Research examines effects of orthostatic hypotension in adults, children

A simple variation to the tried and true method of checking blood pressure can reveal startling information about both older and younger persons, new research suggests.

4 Aug 2010

New study of breast cancer survivors may help physicians ease side effect of treatments

A new study of breast cancer survivors may help physicians ease a common side effect of cancer treatments. The collaborative research by Eva Sevick, Ph.D., Director of the Center for Molecular Imaging at the University of Texas Health Science Center in Houston, and Caroline Fife, M.D., Director of the Memorial Herman Wound Care Clinic at UTHSC, could bring relief to millions.

4 Aug 2010

Blood coagulation, antimicrobial defence processes are functionally coupled: Research

The adaptive immune system can recognize and respond specifically to particular infectious agents. But the first line of defence against pathogens is the so-called innate immune system. This system reacts to invaders by initiating unspecific inflammatory responses which attract various types of specialized cells such as neutrophils to the site of the incursion.

4 Aug 2010

Targacept licenses Cornerstone technology for inflammatory disorders program

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics(TM), today announced that it has added to its program for inflammatory disorders by entering into an exclusive worldwide license agreement with Cornerstone Therapeutics Inc. The agreement grants Targacept rights to Cornerstone's NNR-based patents, as well as its library of preclinical compounds that act on the alpha7 or other nicotinic receptors.

4 Aug 2010

MabCure files provisional patent application for ovarian cancer diagnostic antibodies

Biotechnology company MabCure, Inc. today announced the company has filed a provisional patent application for its ovarian cancer diagnostic antibodies with the U.S. Patent and Trademark Office. The filing was based on positive results of a recent study that showed MabCure's tumor-specific monoclonal antibodies (MAbs) successfully identified ovarian cancer in blood (94 percent) and distinguished it from benign tumors of the ovaries or healthy blood obtained from men and women.

4 Aug 2010

Definiens launches Tissue Studio 2.0 image analysis software for digital pathology

Definiens today announced the introduction of Definiens Tissue Studio™ 2.0, the latest version of the company's leading image analysis software for digital pathology.

4 Aug 2010

Achievement of tenth milestone triggers EUR 2.5 million payment from Boehringer Ingelheim to Evotec

Evotec AG today announced that its research alliance with Boehringer Ingelheim has reached a milestone, triggering a payment of EUR 2.5 million to Evotec. The milestone reached was the selection of a candidate compound for pre-development studies in an inflammation and immunology programme.

4 Aug 2010

Researchers identify TACI; MyD88 activates immune system against infection

Researchers from Mount Sinai School of Medicine have found a new mechanism that explains how certain immune cells are activated to create protective antibodies against infections or pathological antibodies such as those present in autoimmune diseases like lupus and rheumatoid arthritis. The research is published online in the September issue of Nature Immunology.

4 Aug 2010

Study shows link between fructose and pancreatic cancer proliferation

Pancreatic cancers use the sugar fructose, very common in the Western diet, to activate a key cellular pathway that drives cell division, helping the cancer to grow more quickly, a study by researchers at UCLA's Jonsson Comprehensive Cancer Center has found.

4 Aug 2010

Study shows oral contraceptive use increases risk of breast cancer in African American women

Investigators from the Slone Epidemiology Center at Boston University School of Medicine have reported that African American women who use oral contraceptives have a greater likelihood of developing breast cancer than nonusers. The study results, recently published on-line in Cancer Epidemiology Biomarkers and Prevention, were based on data from the Black Women's Health Study, a large follow-up study of 59,000 African American women from across the U.S. conducted by investigators at the Slone Epidemiology Center since 1995.

4 Aug 2010

Periodontal disease may increase risk of cognitive dysfunction: Researchers

NYU dental researchers have found the first long-term evidence that periodontal (gum) disease may increase the risk of cognitive dysfunction associated with Alzheimer's disease in healthy individuals as well as in those who already are cognitively impaired.

4 Aug 2010

Scientists discover single-chain protein to destroy GBM cancer cells

A major breakthrough in how to target and destroy the most malignant and aggressive brain cancer cells has been made by researchers at Wake Forest University Baptist Medical Center.Scientists have identified a way to target and destroy Glioblastoma multiforme (GBM) cells without harming healthy cells.

4 Aug 2010

Sensory dysfunction affects quality of life of patients with Autism

The way the brain reacts differently to the sense of touch in people with Autism will be examined as part of an innovative Cardiff University study designed to create better understanding of the condition. Dr David McGonigle from Cardiff University's Schools of Psychology and Biosciences will use the latest brain imaging techniques to create a clearer picture of how touch is processed differently.

4 Aug 2010

Research findings show normal rise and fall in triglycerides

When the circadian rhythm gets thrown off, it could come with an unexpected side effect: high triglycerides. The discovery, based on studies in mice with a "broken clock," helps to explain the normal rise and fall in triglycerides, which happens at about the same time each day, according to researchers who report their findings in the August issue of Cell Metabolism, a Cell Press publication.

4 Aug 2010

Cancer cells utilize fructose as an alternative to glucose for fueling growth: Study

A study published in the August issue of Cancer Research has resulted in several premature and potentially misleading conclusions when it comes to fructose and its effect on pancreatic tumor cells. Unfortunately, the media covering this story, and even the authors, have been too quick to extrapolate the results of laboratory research on pure fructose to real-world conditions, which is not appropriate or helpful to consumers.

4 Aug 2010

Scientists identify IRP proteins to ensure iron balance for cell survival

Most organisms need iron to survive, but too much iron is toxic, and can cause fatal organ failure. The same is true inside cells, where iron balance must also be maintained. In a study published today in Cell Metabolism, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered that a group of proteins named IRPs ensure that this iron balance is kept and as such are essential for cell survival. More specifically, they found that IRPs are required for the functioning of mitochondria, the cell's energy factories.

4 Aug 2010

Medical Research News

Certain human leukemias can be treated by targeting stem-cell microRNAs: Research

Thinking of God reduces distress to anxiety-provoking mistakes: Study

Simmons Comprehensive Cancer Center at UT Southwestern attains National Cancer Institute designation

Study links sea sponge genome sequence with first animals and cancer

Research examines effects of orthostatic hypotension in adults, children

New study of breast cancer survivors may help physicians ease side effect of treatments

Blood coagulation, antimicrobial defence processes are functionally coupled: Research

Targacept licenses Cornerstone technology for inflammatory disorders program

MabCure files provisional patent application for ovarian cancer diagnostic antibodies

Definiens launches Tissue Studio 2.0 image analysis software for digital pathology

Achievement of tenth milestone triggers EUR 2.5 million payment from Boehringer Ingelheim to Evotec

Researchers identify TACI; MyD88 activates immune system against infection

Study shows link between fructose and pancreatic cancer proliferation

Study shows oral contraceptive use increases risk of breast cancer in African American women

Periodontal disease may increase risk of cognitive dysfunction: Researchers

Scientists discover single-chain protein to destroy GBM cancer cells

Sensory dysfunction affects quality of life of patients with Autism

Research findings show normal rise and fall in triglycerides

Cancer cells utilize fructose as an alternative to glucose for fueling growth: Study

Scientists identify IRP proteins to ensure iron balance for cell survival

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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