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Echo acoustic liquid handler improves discovery of potential therapeutics

When the revolutionary Echo® acoustic liquid handler is used in the process of discovering potential therapeutics, important drug candidates are identified that are missed using traditional liquid handlers. In a recently issued patent, the global pharmaceutical company AstraZeneca describes the discovery of a novel set of potential cancer therapeutics that was found only when the Echo system was used. Other major pharmaceutical companies have also reported that the Echo liquid handler was a critical platform in discovering drug candidates.

15 Dec 2010

DSM licenses c-LEcta's alcohol dehydrogenases for enzyme screening programs

DSM Pharmaceutical Products, the custom manufacturing organization of Royal DSM NV, today announces a license agreement with c-LEcta GmbH for proprietary screening technology.

15 Dec 2010

Study broadens understanding of role of IDH1 and IDH2 mutations in AML

Agios Pharmaceuticals, the leading biopharmaceutical company focused on discovering and developing novel drugs in the rapidly emerging field of cancer metabolism, today announced the publication of a paper in Cancer Cell that illuminates the mechanism by which 2-hydroxyglutarate (2HG), and the mutations in the metabolic genes IDH1 and IDH2 that produce it, may be driving the growth of tumors in patients with acute myeloid leukemia (AML).

15 Dec 2010

Study suggests unexpected role for NLRP3 protein in cancer vaccine development

The promise of vaccines targeted against various types of cancer has raised the hopes of patients and their families. The reality, however, is that these promising treatments are difficult to develop. One of the challenges is identifying a discrete cellular target to stop cancer growth without inactivating the immune system. Scientists at UNC Lineberger Comprehensive Cancer Center report a laboratory finding that has the potential to increase the effectiveness of therapeutic cancer vaccines.

15 Dec 2010

Reuters looks at cost-effectiveness of pursuing malaria vaccine, eradication

Reuters examines the effort to create an effective malaria vaccine and asks: "[I]s the vaccine - and the global health community's aim of completely eradicating a disease that kills a child every 45 seconds - really worth the money?"

15 Dec 2010

Angiogenesis inhibition is a validated strategy for cancer therapy

Scientists at the Dana-Farber Cancer Institute may have uncovered a mechanism for blocking tumor angiogenesis that involves the patient's immune system, according to findings published in Cancer Research, a journal of the American Association for Cancer Research.

15 Dec 2010

German Research Foundation opens four new research units

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is establishing four new Research Units. The decision was made by the DFG Senate at its December session in Bonn. The establishment of the Research Units will enable researchers to explore prevailing topical questions and generate new approaches in their respective fields.

15 Dec 2010

Hemispherx granted extension to modify Ampligen NDA for CFS indication

Hemispherx Biopharma, Inc. announced today that the Food and Drug Administration (FDA) granted a 12 month extension for the Company to modify its NDA in response to a Complete Response Letter (CRL) received November 25, 2009 for the CFS indication.

15 Dec 2010

BUSM awarded NCI EDRN, DOD grants to develop novel procedures for early detection of lung cancer

Researchers from Boston University School of Medicine (BUSM) have been awarded a five-year, $2 million grant from the National Cancer Institute (NCI) Early Detection Research Network (EDRN), as well as a four-year, $1.3 million grant from the Department of Defense (DOD). These grants will allow the scientists to develop novel and complementary procedures for early detection of lung cancer in high-risk patients.

15 Dec 2010

UCSF scientists explain why oligodendroglioma is more responsive to therapy than other brain tumors

For patients with glioma, the most common primary brain tumor, new findings may explain why current therapies fail to eradicate the cancer. A UCSF-led team of scientists has identified for the first time that progenitor rather than neural stem cells underly a type of glioma called oligodendroglioma.

15 Dec 2010

Study links large waistline to increased risk of heart problems and type 2 diabetes

Researchers at Eastern Virginia Medical School’s Strelitz Diabetes Center and the school’s department of physiological sciences have published research showing a strong link between a large waistline and increased risk of Type 2 diabetes and cardiovascular disease.

14 Dec 2010

DARPA awards Pulmatrix $5.7 million grant to advance iCALM therapies

Pulmatrix, a clinical stage biotechnology company discovering and developing a new class of therapies for the prevention, treatment and control of respiratory diseases, today announced that it has been awarded a grant for $5.7 million from the Defense Advanced Research Projects Agency (DARPA), a component of the Department of Defense (DOD), focused on identifying and advancing novel technologies to support defense of our nation's soldiers and civilian population.

14 Dec 2010

60% of Americans concerned about negative health impact of beverages

A recent BeveragePulse.com study by Concept Catalysts and iModerate Research Technologies, found that 60% of Americans are concerned about the negative health impact of the beverages they drink and the majority of them will be drinking healthier beverages in the next 12 months. The study also shows that health concerns are the primary driver of recent changes in what consumers buy and drink and will remain the main driver of change for some time to come. Currently, 74% of Americans do not think that beverage companies are concerned about their health.

14 Dec 2010

Series of papers highlights challenges with moving African-developed drugs, technology forward

"Africa is struggling to turn local discoveries into drugs and other health care inventions," according to studies published in Science and BMC International Health and Human Rights, Nature News reports (Nordling, 12/12).

14 Dec 2010

Pruritic nodules and aluminium allergy arise after vaccinations or treatments for allergies

Allergic contact dermatitis from aluminium has previously been considered very unusual. However, there are now reports of pruritic nodules and aluminium allergy arising after vaccinations or treatments for allergies.

14 Dec 2010

Scientists perform metagenomic analysis of bacterial immune system for personalized oral health care

The human body is home to a complex ecosystem of microbes increasingly recognized as having a critical role in both health and disease.

14 Dec 2010

Lack of 'systematic reviews' in stroke research lead to waste of time, resources

Research being conducted into stroke needs to slow down and take stock if a therapeutic breakthrough is ever likely to happen, says a leading stroke expert.

14 Dec 2010

We live longer, but not healthier

Increased life expectancy in the United States has not been accompanied by more years of perfect health, reveals new research published in the December issue of the Journal of Gerontology.

14 Dec 2010

American Epilepsy Society recognizes neuroscientist for basic science advances

Douglas A. Coulter, Ph.D., a neuroscientist at The Children's Hospital of Philadelphia, received the 2010 Epilepsy Research Recognition Award for Basic Science from the American Epilepsy Society. The Society honored Dr. Coulter's pioneering contributions to epilepsy research on Monday, Dec. 6 at its Annual Meeting in San Antonio.

14 Dec 2010

EHSI negotiates potential option agreement with Regenetech for Rotary Cell Culture System

Emerging Healthcare Solutions, Inc. is negotiating a potential option agreement with biotech firm Regenetech, Inc.

14 Dec 2010

Medical Research News

Echo acoustic liquid handler improves discovery of potential therapeutics

DSM licenses c-LEcta's alcohol dehydrogenases for enzyme screening programs

Study broadens understanding of role of IDH1 and IDH2 mutations in AML

Study suggests unexpected role for NLRP3 protein in cancer vaccine development

Reuters looks at cost-effectiveness of pursuing malaria vaccine, eradication

Angiogenesis inhibition is a validated strategy for cancer therapy

German Research Foundation opens four new research units

Hemispherx granted extension to modify Ampligen NDA for CFS indication

BUSM awarded NCI EDRN, DOD grants to develop novel procedures for early detection of lung cancer

UCSF scientists explain why oligodendroglioma is more responsive to therapy than other brain tumors

Study links large waistline to increased risk of heart problems and type 2 diabetes

DARPA awards Pulmatrix $5.7 million grant to advance iCALM therapies

60% of Americans concerned about negative health impact of beverages

Series of papers highlights challenges with moving African-developed drugs, technology forward

Pruritic nodules and aluminium allergy arise after vaccinations or treatments for allergies

Scientists perform metagenomic analysis of bacterial immune system for personalized oral health care

Lack of 'systematic reviews' in stroke research lead to waste of time, resources

We live longer, but not healthier

American Epilepsy Society recognizes neuroscientist for basic science advances

EHSI negotiates potential option agreement with Regenetech for Rotary Cell Culture System

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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