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Preoperative comorbidity indices predictive in bladder cancer

For patients with urothelial carcinoma of the bladder who are undergoing radical cystectomy, the measurement of preoperative comorbidity indices can improve prognostication in terms of cancer-independent mortality, study results show.

10 Oct 2012

Migraine therapy alleviates more than just the headache

Treating the pain associated with migraine can also improve the social and psychologic problems experienced by individuals affected by the condition, findings from a systematic review suggest.

10 Oct 2012

Nicotine dependence linked to symptom severity in schizophrenia

Nicotine dependence is associated with increased symptom severity in patients with schizophrenia, UK study results show.

10 Oct 2012

Progesterone test could identify nonviable pregnancies

A single progesterone measurement may be useful for predicting nonviable pregnancies in women with pain or bleeding when an ultrasound investigation proves to be inconclusive, say researchers.

10 Oct 2012

Feline leukemia virus becoming uncommon with lymphoma

Rates of feline leukemia virus in domestic cats with lymphoma have decreased in recent years, suggesting alternative etiologies for this cancer subtype, show German study results.

10 Oct 2012

Ranibizumab improves driving prospects for AMD patients

Treatment with ranibizumab can preserve and even improve the perceived driving ability of patients with age-related macular degeneration, show the results of two randomized trials.

10 Oct 2012

Simple test confirms correct catheter placement

Injecting sodium bicarbonate into a peripheral intravenous catheter is a straightforward means of testing its placement and patency in mechanically ventilated children, say researchers.

10 Oct 2012

Bacterial pathogen ‘acutely’ involved in otitis media

Alloiococcus otitidis can be a dominant bacterial pathogen among indigenous Australian children with acute otitis media with perforation, although its main role appears to be that of a secondary pathogen, preliminary study findings suggest.

10 Oct 2012

MDD with subthreshold hypomania ‘should be merged with bipolar II’

Patients with major depressive disorder plus subthreshold hypomania exhibit significant differences in disease course, symptoms, treatment-seeking rates and other characteristics compared with those with major depression alone, research shows.

10 Oct 2012

Hemophilia bleeding risk ‘low’ for childhood sports

Vigorous physical activity is associated with a moderate but transient bleeding risk for hemophilia, resulting in an overall low risk for bleeds, suggests a study of Australian children.

10 Oct 2012

People with diabetic foot ulcers more likely to die prematurely

People with diabetes who develop foot ulcers are at more risk of dying prematurely than those without the complication, finds a new large-scale study. The researchers say the findings highlight the potential need for improved detection and management of those with diabetes and foot ulcers.

10 Oct 2012

Obesity rate high among children admitted to hospital

A study by researchers at the Graduate Entry Medical School, University of Limerick and Dalhousie University in Canada has found 34% of children between 6-12 years old admitted to hospital are overweight or obese.

10 Oct 2012

Endocannabinoid system most vulnerable to cannabis during adolescence

The system of the brain responsible for mediating the effects of cannabis, the endocannabinoid system, is most vulnerable to the drug during adolescence, according to new research.

10 Oct 2012

Neuroprotectant success in aneurysm coiling

Treatment with the novel neuroprotective agent NA-1 reduces the number of ischemic infarcts sustained by patients undergoing coiling of cerebral aneurysms, show the ENACT results.

9 Oct 2012

CT technique could improve COPD classification

The parametric response map technique can be used in chronic obstructive pulmonary disease to distinguish between disease subtypes, say US researchers.

9 Oct 2012

HVLA manipulation comes out top for low-back pain

Spinal high-velocity-low-amplitude manipulation for the treatment of nonspecific low-back pain has shown to be superior to a nonsteroidal anti-inflammatory drug, researchers report.

9 Oct 2012

Transfused blood age does not impact outcomes in premature babies

Using fresh red blood cells for premature babies who need blood transfusions does not improve outcomes over use of standard blood bank donations, show study findings published in JAMA.

9 Oct 2012

High personality disorder comorbidity rates identified in anxiety

A meta-analysis covering 30 years of research has identified high rates of comorbid personality disorders across a number of anxiety disorder subtypes.

9 Oct 2012

PUFA levels reduced in schizophrenia patients

Results from a systematic review and meta-analysis show that erythrocyte membrane concentrations of certain polyunsaturated fatty acids are reduced in the brains of people with schizophrenia.

9 Oct 2012

Kynurenic acid levels increased in bipolar patients with psychotic features

Bipolar disorder patients with a history of psychotic features have higher cerebrospinal fluid concentrations of kynurenic acid (KYNA) than those without such features, research shows.

9 Oct 2012