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Low levels of vitamin D associated with lower lung function in children with asthma

Low levels of vitamin D are associated with lower lung function and greater medication use in children with asthma, according to researchers at National Jewish Health. In a paper published online this week in the Journal of Allergy & Clinical Immunology, Daniel Searing, MD, and his colleagues also reported that vitamin D enhances the activity of corticosteroids, the most effective controller medication for asthma.

16 Apr 2010

New research on EKG signals could help heart patients in future

A physics major's passion for medicine led her into research that could help heart patients in the future.

16 Apr 2010

New study describes impact of chronic pain on black men

Black men with chronic pain related to an accident, injury, illness, surgery or other causes were more likely to experience depression, affective distress and disability than white men with chronic pain, according to a new study by the University of Michigan Health System.

16 Apr 2010

Research may provide better clinical outcomes for patients with aggressive type of brain cancer

A study conducted by a collaborative team led by researchers from the University of Southern California (USC) may lead to better insight into the clinical outcome for some patients with a particularly aggressive type of brain cancer. The research may also provide a framework for development of targeted drug treatments.

16 Apr 2010

Study links cancer growth to sugar-based modification found naturally in the body

Researchers at Drexel University College of Medicine have discovered that a certain type of sugar found naturally in the body is elevated in breast cancer cells and is critical for cancer growth and movement. When researchers reduced and normalized the levels of this sugar, they were able to slow the growth of the cancer cells and block invasion. The findings, published in the March 1 issue of Oncogene, represent a potential new therapeutic target for treating aggressive forms of breast cancer.

15 Apr 2010

Sorrento Therapeutics completes construction of fully human mAbs library

Sorrento Therapeutics, Inc. today announced that it has completed the construction of an extensive library of full-length, fully human monoclonal antibodies (mAbs). Initial analysis indicates a potential diversity of more than one trillion unique mAbs. The company believes this makes its library the largest full-length, fully human antibody library available for drug discovery and development partnerships.

15 Apr 2010

Celgene, Agios Pharmaceuticals form global strategic collaboration on targeting cancer metabolism

Celgene Corporation and Agios Pharmaceuticals Inc., a privately-held biotechnology company, today announced the formation of a global strategic collaboration focused on targeting cancer metabolism. The goal of the collaboration is to discover, develop, and deliver novel disease-altering therapies in oncology based on the transformational science of Agios' innovative cancer metabolism research platform. This platform is based on the concept that targeting key metabolic enzymes unique to rapidly proliferating cancer cells can "starve" the cancer.

15 Apr 2010

Study finds variation in H1N1 infection risks and antibody levels: JAMA

An analysis of blood samples taken before, during and after an epidemic wave of influenza A(H1N1) in Singapore in 2009 finds variation in infection risks and antibody levels, with younger age groups and military personnel having higher infection rates than other groups, according to a study in the April 14 issue of JAMA.

15 Apr 2010

Novel drug helps discover mechanisms underlying female sexual arousal

By using a novel prototype drug, researchers have discovered more about the mechanisms underlying female sexual arousal. These findings are published today in the British Journal of Pharmacology.

15 Apr 2010

Ibuprofen demonstrates efficacy over acetaminophen for treatment of pain and fever

Cumberland Pharmaceuticals Inc. today announced results from a meta-analysis comparing the efficacy and safety of ibuprofen and acetaminophen, which was published in the March edition of the peer-reviewed journal The Annals of Pharmacotherapy. The publication notes that in a majority of evaluated studies ibuprofen demonstrated superior efficacy compared to acetaminophen for the treatment of pain and fever, and found no significant safety differences between the drugs.

15 Apr 2010

New findings may allow clinicians to prevent complications in pregnancy

Researchers at Mount Sinai School of Medicine have found that epigenetic marks on human placentas change from the first trimester of pregnancy to the third, a discovery that may allow clinicians to prevent complications in pregnancy.

15 Apr 2010

MDA awards over $21M in grants for advancing critical neuromuscular research

Forty-two medical researchers and their labs have been awarded more than $21 million in grants by the Muscular Dystrophy Association to advance critical neuromuscular research in 2010. Many of the grants are multi-year awards to be dispersed over the next three years.

15 Apr 2010

Earplugs and eye masks could help intensive care patients get better night's sleep

Eye masks and earplugs could help hospital patients get a better night's sleep. Researchers writing in BioMed Central's open access journal Critical Care investigated their effect on sleep quality in a simulated intensive care environment.

15 Apr 2010

Fast foods contain insufficient iodine content, says new research

With one in four Americans reportedly consuming fast food on a daily basis, new research which will be released on Thursday, April 22nd at the American Association of Clinical Endocrinologists (AACE) 19th Annual Meeting & Clinical Congress indicating another reason to avoid fast food; It may also be lacking in appropriate amounts of iodine.

15 Apr 2010

Pancreatic Cancer Action Network, AACR awarded four Innovative Grants for pancreatic cancer research

The Pancreatic Cancer Action Network and the American Association for Cancer Research awarded four Innovative Grants; three Career Development Awards; one Pathway to Leadership Grant; and one Fellowship Award to outstanding researchers for their innovative research proposals which have the potential to lead to medical breakthroughs in the treatment of pancreatic cancer.

15 Apr 2010

Patients with RLS using rotigotine achieve sustained improvements

New data presented at the 62nd American Academy of Neurology annual meeting in Toronto, Canada, showed that patients with moderate to severe Restless Legs Syndrome using rotigotine achieved sustained improvements in symptoms over 5 years of treatment.

15 Apr 2010

Potential new drug for treatment of MS to be presented at AAN Annual Meeting

Researchers from Mount Sinai School of Medicine will present several studies at the American Academy of Neurology Annual Meeting, including a potential new drug for the treatment of multiple sclerosis and surprising trends showing a reduction in the disease's severity. The meeting will take place April 10-17 in Toronto.

15 Apr 2010

Study combines CT and VBM to provide accurate picture of autistic brain

A new study, the first of its kind, combines two complementary analytical brain imaging techniques, to provide a more comprehensive and accurate picture of the neuroanatomy of the autistic brain. The study, published in the April issue of neuroimaging journal Human Brain Mapping, was conducted by researchers at The Montreal Neurological Institute and Hospital - The Neuro, McGill University and the Universit- de Montr-al.

15 Apr 2010

Study provides support for relationship between APOE4 gene and risk of Alzheimer's disease in Latinos

A brain-imaging study published today in the Archives of Neurology suggests that a major genetic risk factor for Alzheimer's disease in the Anglo population is also a risk factor for the disease in Latinos.

15 Apr 2010

Comparing effectiveness of PET and other molecular imaging techniques: SNM receives $48,000 AHRQ grant

SNM has been awarded a $48,000 grant from the Agency for Healthcare Research and Quality (AHRQ) to hold a conference to develop research on the comparative effectiveness of positron emission tomography (PET) and other molecular imaging techniques. The primary emphasis will be on the diagnosis and management of cancer patients, but both cardiology and neurology questions will also be addressed.

15 Apr 2010

Medical Research News

Low levels of vitamin D associated with lower lung function in children with asthma

New research on EKG signals could help heart patients in future

New study describes impact of chronic pain on black men

Research may provide better clinical outcomes for patients with aggressive type of brain cancer

Study links cancer growth to sugar-based modification found naturally in the body

Sorrento Therapeutics completes construction of fully human mAbs library

Celgene, Agios Pharmaceuticals form global strategic collaboration on targeting cancer metabolism

Study finds variation in H1N1 infection risks and antibody levels: JAMA

Novel drug helps discover mechanisms underlying female sexual arousal

Ibuprofen demonstrates efficacy over acetaminophen for treatment of pain and fever

New findings may allow clinicians to prevent complications in pregnancy

MDA awards over $21M in grants for advancing critical neuromuscular research

Earplugs and eye masks could help intensive care patients get better night's sleep

Fast foods contain insufficient iodine content, says new research

Pancreatic Cancer Action Network, AACR awarded four Innovative Grants for pancreatic cancer research

Patients with RLS using rotigotine achieve sustained improvements

Potential new drug for treatment of MS to be presented at AAN Annual Meeting

Study combines CT and VBM to provide accurate picture of autistic brain

Study provides support for relationship between APOE4 gene and risk of Alzheimer's disease in Latinos

Comparing effectiveness of PET and other molecular imaging techniques: SNM receives $48,000 AHRQ grant

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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