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Nematode worm provides model of invasive cancer

A single cell in a 1-millimeter nematode worm is providing valuable new clues into cancer's deadliest behavior -- its ability to put down roots in new tissues after spreading throughout the body.

17 Aug 2009

Running and addiction

Although exercise is good for your health, extreme exercise may be physically addicting. Rats given a drug that produces withdrawal in heroin addicts went into withdrawal after running excessively in exercise wheels, according to new research. Rats that ran the hardest had the most severe withdrawal symptoms.

17 Aug 2009

Mother's immune system may block fetal treatments for blood diseases

Pediatric researchers have resolved an apparent contradiction in the field of prenatal cell transplantation - a medical approach that holds future promise in correcting sickle cell disease and other serious congenital blood disorders. In a new study in animals, the researchers showed that the mother's immune response interferes with the offspring's earlier ability to tolerate transplanted donor cells.

17 Aug 2009

Cognitive behavioral therapy improves sleep and pain in osteoarthritis

A study in the Aug. 15 issue of the Journal of Clinical Sleep Medicine shows that the use of cognitive behavioral therapy for insomnia (CBT-I) is an effective treatment for older patients with osteoarthritis and comorbid insomnia.

16 Aug 2009

Discovery of inherited gene variants that account for 37 percent of childhood acute lymphoblastic leukemia

Scientists at St. Jude Children’s Research Hospital have identified inherited variations in two genes that account for 37 percent of childhood acute lymphoblastic leukemia (ALL), including a gene that may help predict drug response.

16 Aug 2009

Abuse, self-neglect places seniors at increased risk for premature death

Older adults who are subjected to abuse or self-neglect face a greater risk of premature death than other seniors, according to a study published in the medical journal JAMA.

16 Aug 2009

New target for Alzheimer's disease

For close to a decade, pharmaceutical researchers have been in hot pursuit of compounds to activate a key nicotine receptor that plays a role in cognitive processes. Triggering it, they hope, might prevent or even reverse the devastation wrought by Alzheimer’s disease.

16 Aug 2009

New biomarker predicts response to hepatitis C treatment

Researchers have identified the first genetic marker that predicts response to hepatitis C treatments, and a single letter of DNA code appears to make a huge difference. Duke University Medical Center scientists says the biomarker not only predicts who is most likely to respond to treatment and who isn't, but also may explain why there are such different rates of response among racial and ethnic groups, a phenomenon that has puzzled physicians for years.

16 Aug 2009

Novel treatment reduces swollen livers

Viruses need living cells for replication and production of virus progeny. Thus far, antiviral therapy primarily targets viral factors but often induces therapy resistance. New improved therapies attempt to targets cellular factors that are essential for viral replication.

16 Aug 2009

New strategy for inhibiting virus replication

16 Aug 2009

New study suggests possible genetic link between environmental toxins and myeloma

The International Myeloma Foundation (IMF) today said newly published data may provide a possible genetic link between environmental toxins and bone disease in multiple myeloma. Myeloma, also called multiple myeloma, is a cancer of cells in the bone marrow that affect production of blood cells and can damage bone.

14 Aug 2009

Researchers study sleep paralysis

Professor Chris French, has co-authored a paper on sleep paralysis with Julia Santomauro, both of the Anomalistic Psychology Research Unit at Goldsmiths, University of London, which is published in Issue 22 (August 2009) of The Psychologist.

14 Aug 2009

Scientists create new method to detect genetic causes of complex diseases

Computational biologists at Carnegie Mellon University have developed an analytical technique to detect the multiple genetic variations that contribute to complex disease syndromes such as diabetes, asthma and cancer, which are characterized by multiple clinical and molecular traits.

14 Aug 2009

Gay people more likely to have mental health or substance use disorders

Members of ‘sexual minorities’ are around twice as likely as heterosexuals to seek help for mental health issues or substance abuse treatment. A model of treatment-seeking behavior, described in the open access journal BMC Psychiatry supports the idea that lesbian, gay and bisexual people may have specific treatment needs.

14 Aug 2009

Tissue scarring key to link between obesity and diabetes

The team, in collaboration with University Hospital Aintree, the University of Warwick and researchers in Sweden, found that people classified as obese and those with pre-diabetes have raised levels of a protein called SPARC, that can cause tissue scarring.

13 Aug 2009

When cell death goes wrong - scientists gain new insights

Medical Research Council (MRC) scientists have made an important advance in understanding the biological processes involved when cells are prompted to die. The work may help scientists to eventually develop new treatments for the many common diseases and conditions which occur when cell death goes wrong.

13 Aug 2009

New tumour theory could change cancer treatment

University of Sydney researcher Dr Guy Lyons has come up with a new theory of cancer tumours that could change the way we treat cancer and conduct research into its causes.

13 Aug 2009

Discovery of possible genetic link between environmental toxins and bone disease in multiple myeloma

The International Myeloma Foundation (IMF) - supporting research and providing education, advocacy and support for myeloma patients, families, researchers and physicians - today said newly published data may provide a possible genetic link between environmental toxins and bone disease in multiple myeloma.

13 Aug 2009

Human brain distinctly separates living and non-living objects for processing

For unknown reasons, the human brain distinctly separates the handling of images of living things from images of non-living things, processing each image type in a different area of the brain. For years, many scientists have assumed the brain segregated visual information in this manner to optimize processing the images themselves, but new research shows that even in people who have been blind since birth the brain still separates the concepts of living and non-living objects.

13 Aug 2009

Sigma-Aldrich offers customizable synthetic extracellular matrix (ECM) for stem cell research

Sigma-Aldrich (Nasdaq: SIAL) today announced an agreement with Glycosan BioSystems for the sale of HyStem(TM), a fully customizable synthetic extracellular matrix (ECM) for stem cell research. HyStem offers researchers flexibility to tailor microenvironments for their cultured cells that mimic natural in vivo conditions, optimizing stem cell proliferation and differentiation. HyStem was developed by Glycosan BioSystems and will be sold by Sigma-Aldrich under a non-exclusive distribution agreement.

13 Aug 2009