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New understanding on how DNA repair works

One can have a dream, two can make that dream so real, goes a popular song. Now a Weizmann Institute study has revealed that it takes two to perform an essential form of DNA repair.

4 May 2009

New light shed on salt-sensitive hypertension

A high salt intake has been implicated in cardiovascular disease risk for 5000 years. But salt-sensitive hypertension still remains an enigma.

4 May 2009

Calorie restriction causes temporal changes in the liver and skeletal muscle metabolism

Moderate calorie restriction causes temporal changes in the liver and skeletal muscle metabolism, whereas moderate weight loss affects muscle, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

4 May 2009

Memory becomes less efficient very early in Alzheimer's

Even very early in Alzheimer's disease, people become less efficient at separating important from less important information, a new study has found.

4 May 2009

Psyched out by stereotypes: IU research suggests thinking about the positive

In a new study, cognitive scientists have shown that when aware of both a negative and positive stereotype related to performance, women will identify more closely with the positive stereotype, avoiding the harmful impact the negative stereotype unwittingly can have on their performance.

4 May 2009

Discovery of process that controls T cell growth

Identifying one of the processes that plays a role in naïve and memory T-cells' growth and production could one day lead to better vaccines and possibly more effective cancer immunotherapy, said researchers at Baylor College of Medicine and Texas Children's Hospital in a report that appears in the current edition of Nature Immunology.

3 May 2009

Small molecules might block mutant protein production in Huntington's disease

Molecules that selectively interfere with protein production can stop human cells from making the abnormal molecules that cause Huntington's disease, researchers at UT Southwestern Medical Center have found.

3 May 2009

New kind of treatment for sexually transmitted diseases

Yale researchers describe a breakthrough in safe and effective administration of potential antiviral drugs - small interfering RNA (siRNA) molecules that silence genes - the first step in development of a new kind of treatment for sexually transmitted diseases (STDs). The work is reported May 4 as an advance online publication of Nature Materials.

3 May 2009

Research uncovers possible basis of memories for different smells

Ben W. Strowbridge, Ph.D, associate professor of Neuroscience and Physiology/Biophysics, and Yuan Gao, a Ph.D. student in the neurosciences program at Case Western Reserve University School of Medicine, are the first to discover a form of synaptic memory in the olfactory bulb, the part of the brain that processes the sense of smell.

3 May 2009

Personalizing therapy the key strategy for survival in lung cancer

Cancer vaccines and targeted therapies are beginning to offer new treatment options following surgery for patients with early stages of lung cancer, experts said at the first European Multidisciplinary Conference in Thoracic Oncology (EMCTO) in Lugano, Switzerland (1-3 May 2009).

3 May 2009

RNA production revs up during cell-to-cell contact

MicroRNAs are single-stranded snippets that, not long ago, were given short shrift as genetic junk. Now that studies have shown they regulate genes involved in normal functioning as well as diseases such as cancer, everyone wants to know: What regulates microRNAs?

3 May 2009

Chemical found in medical devices impairs heart function

Researchers at the Johns Hopkins University School of Medicine have found that a chemical commonly used in the production of such medical plastic devices as intravenous (IV) bags and catheters can impair heart function in rats.

3 May 2009

Wealthier people choose better diets - but pay more per calorie

As people become more educated, studies have demonstrated that they tend to choose foods that are lower in calories but higher in nutrients. They also pay more. In a study published in the May 2009 issue of the Journal of the American Dietetic Association, researchers from the University of Washington compared the eating habits and food costs of a sample of 164 adults in the Seattle, Washington area.

3 May 2009

Extremely shy? - help is at hand

Help is at hand for those who suffer from extreme shyness. Shyness in its extreme form can have a huge impact on peoples' lives because it results in an avoidance of the usual common social situations, such as meeting new people or going on a date, and can also have an impact on work situations.

30 Apr 2009

Many patients in intensive care are deficient in vitamin D

Australian researchers have discovered that many critically ill patients in intensive care are deficient in vitamin D.

30 Apr 2009

CDH10 gene found to play a critical role in prenatal risk of autism

UCLA scientists, in partnership with 30 research institutions across the country, have identified a new gene variant that is highly common in autistic children.

30 Apr 2009

Breakthrough in understanding of how blood cells develop and divide

A West Australian research team has made the world-first discovery a 'pied piper' molecule within blood cells, called Liar, that leads other molecules into the nucleus of the cell, and could offer a key in treating prostate, breast and colon cancers as well as leukemia.

30 Apr 2009

A systems biology map of iron metabolism

Scientists at the Wake Forest University School of Medicine, the University of Manchester in the United Kingdom, and the Virginia Bioinformatics Institute at Virginia Tech have taken the first steps toward constructing a systems biology map of iron metabolism.

30 Apr 2009

DNA protecting protein helps cancer drug to kill cells

Some DNA repair enzymes can become double-edged swords - If they work too slowly, they can block necessary cell maintenance and contribute to cell death.

30 Apr 2009