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New insights into transcription factors in human cells

Bioinformatics researchers from UC San Diego just moved closer to unlocking the mystery of how human cells switch from "proliferation mode" to "specialization mode."

20 Apr 2009

Human lung tumors can eliminate Vitamin D

Human lung tumors have the ability to eliminate Vitamin D, a hormone with anti-cancer activity, a new study from the University of Pittsburgh Cancer Institute (UPCI) suggests.

20 Apr 2009

Human foetal stem cells can effectively be used to treat back leg ischaemic ulcers

Treatment of chronic wounds is a continuing clinical problem and socio-economic burden with diabetic foot ulcers alone costing the NHS £300 million a year.

20 Apr 2009

Overexpression of PEA-15 protein shrinks breast cancer tumors

Overexpression of PEA-15, which binds and drags an oncoprotein out of the cell nucleus where it fuels cancer growth, steeply reduced breast cancer tumors in a preclinical experiment, researchers at The University of Texas M. D. Anderson Cancer Center reported at the 100th annual meeting of the American Association for Cancer Research.

20 Apr 2009

Grouping muscles to make controlling limbs easier

With more than 30 muscles in your arm, controlling movement -- whether it's grasping a glass or throwing a baseball -- is a complex task that potentially takes into account thousands of variables.

20 Apr 2009

Genetic source of rare cancer pleuropulmonary blastoma discovered

The search for the cause of an inherited form of a rare, aggressive childhood lung cancer has uncovered important information about how the cancer develops and potentially sheds light on the development of other cancers.

20 Apr 2009

First compound for receptors in schizophrenia and Alzheimer's holds promise

For almost 20 years, pharmacological companies have known that certain compounds that activate two specific CNS receptors, causing them to release the neurotransmitter acetylcholine, are effective in treating the cognitive and motor problems related to both schizophrenia and Alzheimer's disease (AD).

20 Apr 2009

Fulvestrant influences the effects of chemotherapy drugs on breast cancer cells

Researchers from The Cancer Institute of New Jersey (CINJ) are converging on Denver for the 100th Annual Meeting of the American Association for Cancer Research (AACR) to share their findings on a combined treatment targeting breast cancer that is stimulated by the hormone estrogen (estrogen receptive positive).

20 Apr 2009

First noninvasive technique to accurately predict mutations in human brain tumors

Donald O'Rourke, MD, Associate Professor of Neurosurgery at the University of Pennsylvania School of Medicine and colleagues, were able to accurately predict the specific genetic mutation that caused brain cancer in a group of patients studied using magnetic resonance imaging (MRI).

20 Apr 2009

Genetic variations in inflammation pathway may predict risk of invasive bladder cancer

Genetic variations in the inflammation pathway may predict who would respond to Bacillus-Calmette-Guerin (BCG) treatment and who might experience a recurrence among patients with non-muscle invasive bladder cancer, according to data presented at the American Association for Cancer Research 100th Annual Meeting 2009.

20 Apr 2009

Nanoparticle delivery of a fully functioning copy of P53 tumor suppressor gene

Dr. Esther Chang describes the most recent developments in human trials of the first systemic, non-viral, tumor-targeted, nanoparticle method designed to restore normal gene function to tumor cells while completely bypassing normal tissue April 21 at an American Association of Anatomists (AAA) scientific session at Experimental Biology 2009 in New Orleans.

20 Apr 2009

Research examines the way distraction affects consumers' product decisions

Remember when the answer to a big question came to you in the shower?

20 Apr 2009

Researchers identify mechanism by which an anti-TNF therapy impairs host defense against tuberculosis

The life of many individuals with inflammatory diseases such as rheumatoid arthritis has been dramatically improved by treatment with drugs that target the protein TNF, so called anti-TNF therapies.

20 Apr 2009

Effect of 18F-FDG PET/CT in esophageal cancer patients with early recurrence lesions

In the initial staging of esophageal cancer, preoperative PET scan may be useful in detecting additional cases of metastatic disease before costly and toxic definitive therapy.

20 Apr 2009

Chemopreventive isothiocyanates selectively depletes mutant p53 in tumor cells

Researchers at Lombardi Comprehensive Cancer Center at Georgetown University Medical Center have demonstrated that naturally-occurring compounds can selectively deplete mutant p53 and restore "wild type" function to p53 in a variety of tumor cells.

20 Apr 2009

Discovery of key processes in the brain that control perception of emotional events

Research performed by Nicole Lauzon and Dr. Steven Laviolette of the Schulich School of Medicine & Dentistry at The University of Western Ontario has found key processes in the brain that control the emotional significance of our experiences and how we form memories of them.

20 Apr 2009

Statins may be useful in patients with tamoxifen-resistant breast cancer

Breast cancer cells in the laboratory that don't respond to tamoxifen may be producing high amounts of cholesterol in order to provide a kind of shield against the drug, say researchers at Georgetown University Medical Center (GUMC).

20 Apr 2009

Complications, death rates similar at bariatric surgery centers of excellence, other hospitals

Patients who undergo bariatric surgery at hospitals designated as centers of excellence do not appear to have lower mortality rates or lower rates of complications than those whose procedures are performed at other hospitals, according to a report in the April issue of Archives of Surgery, one of the JAMA/Archives journals.

20 Apr 2009

Consumers of all ages drinking more lower-calorie beverages

At Experimental Biology 2009, Dr. Maureen Storey, senior vice president of science policy for the American Beverage Association, today briefed colleagues on her new analysis indicating that consumers of all ages are drinking more lower-calorie beverages than they did several years ago.

20 Apr 2009

Kingston University research aims to improve 'chemo' treatment for cancer sufferers

A Kingston University pharmacist has secured funding to explore ways to improve chemotherapy treatment for cancer sufferers.

20 Apr 2009

Medical Research News

New insights into transcription factors in human cells

Human lung tumors can eliminate Vitamin D

Human foetal stem cells can effectively be used to treat back leg ischaemic ulcers

Overexpression of PEA-15 protein shrinks breast cancer tumors

Grouping muscles to make controlling limbs easier

Genetic source of rare cancer pleuropulmonary blastoma discovered

First compound for receptors in schizophrenia and Alzheimer's holds promise

Fulvestrant influences the effects of chemotherapy drugs on breast cancer cells

First noninvasive technique to accurately predict mutations in human brain tumors

Genetic variations in inflammation pathway may predict risk of invasive bladder cancer

Nanoparticle delivery of a fully functioning copy of P53 tumor suppressor gene

Research examines the way distraction affects consumers' product decisions

Researchers identify mechanism by which an anti-TNF therapy impairs host defense against tuberculosis

Effect of 18F-FDG PET/CT in esophageal cancer patients with early recurrence lesions

Chemopreventive isothiocyanates selectively depletes mutant p53 in tumor cells

Discovery of key processes in the brain that control perception of emotional events

Statins may be useful in patients with tamoxifen-resistant breast cancer

Complications, death rates similar at bariatric surgery centers of excellence, other hospitals

Consumers of all ages drinking more lower-calorie beverages

Kingston University research aims to improve 'chemo' treatment for cancer sufferers

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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