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Step towards new cancer drugs

The gene Myc is an important factor for the growth of organisms by cell division.

20 Mar 2009

Cherries show promise in osteoarthritis pain relief

For the estimated 27 million Americans who suffer from osteoarthritis, pain relief may come with a cherry on top.

20 Mar 2009

Drinking alcohol is the greatest risk factor for acetaldehyde-related cancer

New evidence by researchers at the Centre for Addiction and Mental Health (CAMH) and researchers in Germany shows that drinking alcohol is the greatest risk factor for acetaldehyde-related cancer.

20 Mar 2009

Paradigm shift in the regulation of immune response

Over the past decade various pieces of the puzzle how signal transmission controls immunity have been coming together.

20 Mar 2009

Epigenetic mark guides stem cells toward their destiny

Not all stem cells are completely blank slates. Some, known as adult stem cells, have already partially embraced their fates and are capable of becoming only cells of a particular type of tissue. So how do these tissue-specific stem cells restrict their fate?

19 Mar 2009

Understanding mental illness through gene-environment interactions

Biological Psychiatry, published by Elsevier, is very pleased to present a special section of its February 1st issue devoted to fundamental new insights into epigenetics, a field of research devoted to understanding how the environment can produce long-lasting or even heritable changes in gene function without altering the DNA sequence.

17 Mar 2009

Superbug complicates treatment of infections in cystic fibrosis

The unexpected behaviour of a family of "superbugs" called the Burkholderia cepacia complex (Bcc) could have implications for the treatment of cystic fibrosis (CF) patients.

17 Mar 2009

Study shows moderate intensity walking means 100 steps per minute

The benefits of moderate physical activity to general health and well-being are well known.

17 Mar 2009

Intelligence is strongly influenced by the quality of the brain's axons

They say a picture tells a thousand stories, but can it also tell how smart you are? Actually, say UCLA researchers, it can.

17 Mar 2009

Why low GI diet makes you feel full

Eating a meal with a low GI (glycaemic index) increases gut hormone production which leads to suppression of appetite and the feeling of fullness.

17 Mar 2009

New tumor markers determine therapy intensity

Characteristic changes in the DNA of medulloblastoma, the most frequent malignant brain tumor in childhood, indicate precisely how aggressively the tumor will continue to spread and what the chances of disease relapse are.

17 Mar 2009

New strategy to weaken traumatic memories

Imagine that you have been in combat and that you have watched your closest friend die in front of you.

17 Mar 2009

MicroRNA undermines tumor suppression

Scientists at the Whitehead Institute for Biomedical Research and the National University of Singapore have discovered the first microRNA (miRNA) capable of directly tamping down the activity of the well known tumor-suppressor gene, p53, While p53 functions to prevent tumor formation, the p53 gene is thought to malfunction in more than 50% of cancerous tumors.

17 Mar 2009

Alzheimer's mechanism suggests combination therapy needed

Researchers at the University of Illinois at Chicago College of Medicine have discovered a mode of action for mysterious but diagnostic protein snarls found in the brains of Alzheimer's patients that suggests a one-two punch of therapy may be needed to combat the neurodegenerative disease.

17 Mar 2009

Lung cancer: Molecular scissors determine therapy effectiveness

In the past few years, a number of anti-cancer drugs have been developed which are directed selectively against specific key molecules of tumor cells.

17 Mar 2009

Link between religious coping and aggressive treatment in terminally ill cancer patients

In a new study of terminally ill cancer patients, researchers at Dana-Farber Cancer Institute found that those who draw on religion to cope with their illness are more likely to receive intensive, life-prolonging medical care as death approaches –– treatment that often entails a lower quality of life in patients' final days.

17 Mar 2009

HPV vaccine may prevent preterm births

Chronic human papilloma virus (HPV)-infections can lead to cellular changes in the cervix that can be a pre-stage to cervical cancer.

17 Mar 2009

Frankincense oil may be an inexpensive alternative therapy for bladder cancer

Originating from Africa, India, and the Middle East, frankincense oil has been found to have many medicinal benefits.

17 Mar 2009

Emotions and emotional control in eating disorders: predictor role and emotional profiles

A Ph.D. thesis at the University of the Basque Country has analyzed the role played by a number of emotional variables, such as the way in which negative emotions are controlled or attitudes to emotional expression, and to use these variables as tools to predict the possibility of suffering an eating disorder.

17 Mar 2009

Drug being used to improve cognition affects dopamine, suggesting potential for abuse

Preliminary research in healthy men suggests that the narcolepsy drug modafinil, increasingly being used to enhance cognitive abilities, affects the activity of dopamine in the brain in a way that may create the potential for abuse and dependence, according to a study in the March 18 issue of JAMA.

17 Mar 2009