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Single submission of orphan drug designation annual report for both FDA and EMA

In recognition of World Rare Disease Day, the U.S. Food and Drug Administration and the European Medicines Agency (EMA) today announced a more streamlined process to help regulators better identify and share information throughout the development process of orphan drug and biologic products, which are developed specifically to treat rare medical conditions. Both agencies have agreed to accept the submission of a single annual report from sponsors of orphan drug and biologic products designated by both the United States and the European Union.

27 Feb 2010

Stroke incidence and treatment: Racial and geographic disparities

Blacks are more likely to have an undiagnosed key risk factor for stroke and are more likely to have a stroke than whites, according to two studies presented at the American Stroke Association's International Stroke Conference 2010.

27 Feb 2010

UAMS researchers identify age-related mechanism as primary cause of osteoporosis

Marking a shift in decades of thought on the cause of osteoporosis, researchers at the University of Arkansas for Medical Sciences have identified an age-related mechanism - not a decrease of the hormone estrogen - as the primary culprit.

27 Feb 2010

For people who carry common gene variants, smoking increases risk of aneurysm

For people who carry common gene variants, cigarette smoking greatly increases the risk that a blood vessel in the brain will weaken and balloon out - called an aneurysm - which could be life-threatening if it ruptures, according to research presented at the American Stroke Association's International Stroke Conference 2010.

27 Feb 2010

Frequent error in medicine occurs nearly one out of three times a patient is referred to specialist: Study

The most frequent error in medicine seems to occur nearly one out of three times a patient is referred to a specialist. A new study found that nearly a third of patients age 65 and older referred to a specialist are not scheduled for appointments and therefore do not receive the treatment their primary care doctor intended.

27 Feb 2010

Overall incidence of stroke, heart attack and death similar in carotid endarterectomy and stenting procedures

The two major procedures for opening blocked neck arteries to restore blood flow to the brain proved similar in overall long-term safety and efficacy, but showed differences in stroke and heart attack in the weeks following the procedure, according to late-breaking science presented at the American Stroke Association's International Stroke Conference 2010.

27 Feb 2010

BCRI study evaluates the effect of high-doses of vitamin C on inhibition of new blood vessel growth

Bio-Communications Research Institute's recent research study has found that high levels of vitamin C (ascorbate) inhibit the formation of new blood vessel growth to tumors.

27 Feb 2010

iBioLaunch platform technology to be licensed for plant-expressed influenza vaccines project

iBio, Inc. announced today that it has agreed in principle to license its technology, the iBioLaunch™ platform, and provide technology transfer services to G-Con, LLC, a private Texas company, and its affiliates, for the development and manufacture of plant-expressed influenza vaccines at a new facility being constructed in Bryan, Texas. The “GreenVax Project” will show proof of concept for a large-scale vaccine production facility using Nicotiana plants grown hydroponically in a contained environment.

27 Feb 2010

Micrometastases in axillary lymph nodes associated with poorer overall survival in breast cancer patients

Metastases that were 2 millimeters or less in diameter ("micrometastases") in axillary lymph nodes detected on examination of a single section of the lymph nodes were associated with poorer disease-free and overall survival in breast cancer patients, according to a new study published online February 26 in the Journal of the National Cancer Institute.

27 Feb 2010

Evolving sex disparity in midlife stroke prevalence: Further study needed

When it comes to stroke prevalence, it appears that the gender gap is widening. According to a new report from a researcher at the Keck School of Medicine of the University of Southern California (USC), women between the ages of 35 and 64 are almost three times more likely to have a stroke compared to men in the same age group.

26 Feb 2010

Librede to develop technologies for improving ion channel drug discovery and screening at CNSI incubator

Librede Inc. has joined the UCLA on-campus technology incubator space at the California NanoSystems Institute, where the startup company will work on developing technologies to improve ion channel drug discovery and screening.

26 Feb 2010

Massaging advanced cancer patients for 14 minutes can reduce stress: Study

Advanced cancer patients who regularly received massages averaging 14 minutes or more by a partner or family member declined in stress scores over four weeks, according to results of a study reported at the 7th annual conference of the American Psychosocial Oncology Society.

26 Feb 2010

MetLife Foundation Awards for Medical Research in Alzheimer's Disease: Four scientists honored

Complementary approaches to Alzheimer's research were recognized as four scientists received the prestigious MetLife Foundation Awards for Medical Research in Alzheimer's Disease in Washington, D.C.

26 Feb 2010

UCB adopts Enterprise version of NextBio platform

NextBio, developer of an innovative software platform that enables life science researchers to search, discover, and share knowledge locked within public and proprietary data, today announced a license agreement with global biopharmaceutical company UCB, for NextBio Enterprise. NextBio Enterprise offers life sciences organizations unique tools for knowledge discovery and collaboration, seamless integration of internal and external research data, and secure data access.

26 Feb 2010

Supelco launches Ascentis Express Peptide ES-C18 HPLC columns

Supelco, a division of Sigma-Aldrich®, announced today the launch of Ascentis Express Peptide ES-C18, a high-speed, high-performance liquid chromatography (HPLC) column based on a new 160 angstrom Fused-Core™ particle design. This column design exhibits very high column efficiency, providing a stable, reversed phase packing with a pore structure and pore size that is optimized for reversed-phase HPLC separations of peptides and polypeptides.

26 Feb 2010

Mathematics of sleep-wake cycle

Why can't I fall asleep? Will this new medication keep me up all night? Can I sleep off this cold? Despite decades of research, answers to these basic questions about one of our most essential bodily functions remain exceptionally difficult to answer. In fact, researchers still don't fully understand why we even sleep at all. In an effort to better understand the sleep-wake cycle and how it can go awry, researchers at Rensselaer Polytechnic Institute are taking a different approach than the traditional brain scans and sleep studies. They are using mathematics.

26 Feb 2010

New fatigue rating scale predicts increased risk of heart attack in dialysis patients

For dialysis patients, high scores on a new fatigue rating scale predict an increased risk of heart attack or other cardiovascular events, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology.

25 Feb 2010

New research using MRI shows that childhood stress can lead to structural brain changes

New research using magnetic resonance imaging (MRI) shows that childhood stress such as abuse or emotional neglect, in particular when combined with genetic factors, can result in structural brain changes, rendering these people more vulnerable to developing depression. The study led by scientists at Trinity College Dublin has just been published in the international scientific journal, Neuropsychopharmacology.

25 Feb 2010

CFIA approves export of Neovasc's processed pericardial tissue products to Europe

Neovasc Inc., today announced that it has received Canadian Food Inspection Agency (CFIA) approval to export its processed pericardial tissue products to Europe as an "intermediate product" under the requirements of Annex I of EC Regulation # 2007/2006. This approval allows European customers to import Neovasc's porcine and bovine pericardial tissue materials for use in the manufacture of their own medical devices.

25 Feb 2010

Greater access to rehabilitation after TIA needed to prevent future strokes

Transient Ischemic Attacks (TIA) are often called "mini strokes" for good reasons -- the short-term symptoms can mimic a stroke and up to 10 percent of first-time sufferers often experience full-blown strokes within as little as 90 days. Despite the well-known statistics, no post-TIA regimen exists to help prevent future strokes -- but this might be changing.

25 Feb 2010

Medical Research News

Single submission of orphan drug designation annual report for both FDA and EMA

Stroke incidence and treatment: Racial and geographic disparities

UAMS researchers identify age-related mechanism as primary cause of osteoporosis

For people who carry common gene variants, smoking increases risk of aneurysm

Frequent error in medicine occurs nearly one out of three times a patient is referred to specialist: Study

Overall incidence of stroke, heart attack and death similar in carotid endarterectomy and stenting procedures

BCRI study evaluates the effect of high-doses of vitamin C on inhibition of new blood vessel growth

iBioLaunch platform technology to be licensed for plant-expressed influenza vaccines project

Micrometastases in axillary lymph nodes associated with poorer overall survival in breast cancer patients

Evolving sex disparity in midlife stroke prevalence: Further study needed

Librede to develop technologies for improving ion channel drug discovery and screening at CNSI incubator

Massaging advanced cancer patients for 14 minutes can reduce stress: Study

MetLife Foundation Awards for Medical Research in Alzheimer's Disease: Four scientists honored

UCB adopts Enterprise version of NextBio platform

Supelco launches Ascentis Express Peptide ES-C18 HPLC columns

Mathematics of sleep-wake cycle

New fatigue rating scale predicts increased risk of heart attack in dialysis patients

New research using MRI shows that childhood stress can lead to structural brain changes

CFIA approves export of Neovasc's processed pericardial tissue products to Europe

Greater access to rehabilitation after TIA needed to prevent future strokes

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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