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Regulus Therapeutics presents new data on oncology, immune disease and HCV therapeutic programs

Regulus Therapeutics Inc. today announced that new pre-clinical data from multiple therapeutic programs were presented at the “RNA Silencing: Mechanism, Biology and Application” Keystone Symposium held January 14 – 19, 2010 in Keystone, Colorado. Regulus and its collaborators presented data showing microRNA target regulation by anti-miRs, as well as data from therapeutic programs focused on oncology, immune disease and hepatitis C virus (HCV) infection.

18 Jan 2010

OSA adversely affects glucose control in patients with type 2 diabetes

Obstructive Sleep Apnea (OSA) adversely affects glucose control in patients with type 2 diabetes, according to a study conducted by researchers at the University of Chicago.

18 Jan 2010

U.S. DOD awards LUHS $1.6M to continue burn research

Loyola University Health Systems (LUHS) has received a $1.6 million contract from the U.S. Department of Defense (DOD) to research burn injuries, the care of burn wounds and infections and how burns affect the immune system.

18 Jan 2010

New research shows cutting tobacco smoking reduces cancer deaths in Europe

New research on deaths from cancer in Europe concludes that the key priority for continuing to reduce mortality is cutting tobacco smoking. The study shows that, while deaths for men from lung cancer in the EU have declined overall, by 17 % from 1995 to 2004, they rose by 27% for women over the same period.

17 Jan 2010

Bone loss around dental implants more common than previously thought

Bone loss around dental implants is far more common than previously realised, reveals a thesis from the Sahlgrenska Academy at the University of Gothenburg, Sweden. Around a quarter of patients loose some degree of supporting bone around their implants.

14 Jan 2010

Early immune response needed for 'hit-and-hide' cancer viruses

Retroviruses such as HIV and HTLV-1 don't hit-and-run, they hit-and-hide. They slip into host cells and insert their own DNA into the cell's DNA, and from this refuge they establish an infection that lasts a lifetime.

14 Jan 2010

Era of rapid expansion in biomedical research funding began in 1990's ends

After a decade of remarkable growth, total annual funding for biomedical research in the U.S. has decelerated and may have even fallen when adjusted for inflation. That is the conclusion of a study today published in the Journal of the American Medical Association.

13 Jan 2010

Obesity could lead to renal cell cancer: BJUI

Being obese could lead to a greater risk of developing the most common form of renal cell cancer, according to research in the January issue of the UK-based urology journal BJUI.

13 Jan 2010

University of Leicester study provides new insights into preventer and reliever treatments for asthma

A new study at the University of Leicester is probing why asthma relief inhalers might actually make asthma worse- and what can be done about it.

13 Jan 2010

Lead even below level "of concern" for children may impair kidney function

Small amounts of lead in the bodies of healthy children and teens — amounts well below the levels defined as "concerning" by the U.S. Centers for Disease Control and Prevention (CDC) — may worsen kidney function, according to a Johns Hopkins Children's Center study published in the Jan. 11 issue of Archives of Internal Medicine.

12 Jan 2010

Mango effective against colon and breast cancer

Mango. If you know little about this fruit, understand this: It's been found to prevent or stop certain colon and breast cancer cells in the lab.

12 Jan 2010

Research shows diet plans can have a major influence on weight loss

Many people think the success of dieting, seemingly a national obsession following the excesses and resolutions of the holiday season, depends mostly on how hard one tries -- on willpower and dedication. While this does matter, new research has found that a much more subtle aspect of the diets themselves can also have a big influence on the pounds shed -- namely, the perceived complexity of a diet plan's rules and requirements.

12 Jan 2010

Functional disconnection between brain regions in ADHD children

Two brain areas fail to connect when children with attention deficit hyperactivity disorder attempt a task that measures attention, according to researchers at the UC Davis Center for Mind and Brain and M.I.N.D. Institute.

12 Jan 2010

French maritime pine tree extract effective against hemorrhoids

According to the National Digestive Diseases Information Clearinghouse, about half of the U.S. population will have hemorrhoids by the age of 50. While the most common prescription to treat hemorrhoids is over-the-counter remedies, most patients do not report symptoms of acute hemorrhoidal attacks to their doctor until they are in severe distress, including bleeding.

12 Jan 2010

Sage Bionetworks, Pfizer sign new research partnership to analyze advanced network models of cancer

Sage Bionetworks has announced today a new research partnership with Pfizer, Inc. to build, analyze and exploit advanced network models of cancer. Pfizer will provide research funding to Sage to analyze large, globally coherent datasets from Pfizer, Sage and the public domain.

12 Jan 2010

Flawed medical research could lead to children receiving treatment that either does not work or is harmful

Lisa Hartling, co-director for the University of Alberta's Alberta Research Centre for Health Evidence, looked at 163 North American clinical trials involving children by using a new tool that rates the risk of bias, meaning the benefits and safety of the treatments may have been exaggerated.

12 Jan 2010

Lives of 400 Swedes can be saved annually if side effects of pharmaceuticals prevented

A scientific study indicates that the lives of 400 Swedes could be saved annually if measures were taken to prevent side effects of pharmaceuticals. Now these researchers in Sweden, at the Nordic School of Public Health (NHV) and elsewhere, have reviewed randomly selected deaths in three Swedish counties and found that 14 percent of these deaths could have been avoided if a drug had been replaced or if the dosage had been lowered.

11 Jan 2010

Research into "chemical chaperone" may lead to new treatments for heart attacks

Researchers at the Indiana University and Stanford University schools of medicine have determined how a "chemical chaperone" does its job in the body, which could lead to a new class of drugs to help reduce the muscle damage caused by heart attacks.

10 Jan 2010

Genital complexities do matter when hooking up with opposite sex, says UC researcher

Charles Darwin spent eight years studying barnacles and their genitalia. In much less time than that, University of Cincinnati evolutionary biologist Michal Polak (and co-author Arash Rashed now at the University of California, Berkeley) have confirmed one of Darwin's theories: that genitalia complexities in some male species have developed because they assist the male in "holding her securely."

8 Jan 2010

NEH awards Challenge Grant to The Center for the History and Ethics of Public Health

The National Endowment for Humanities (NEH) has awarded a Challenge Grant to The Center for the History and Ethics of Public Health at Columbia University's Mailman School of Public Health.

7 Jan 2010