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Discovery of genetic switch critical for cell survival in Hypoxia

Researchers at the University of California, San Diego School of Medicine have identified a critical metabolic "switch" in fruit flies that helps oxygen-deprived cells survive. "A transcriptional suppressor, called hairy, is crucial for reducing the mismatch between supply and demand of oxygen," said Dan Zhou, first author on the study, published October 17 in the open-access journal PLoS Genetics.

21 Oct 2008

Laser treatment works well on sun-damaged skin

Researchers in the United States have found that sun-damaged skin responds well to laser treatment - which is good news for people with skin badly damaged by exposure to the sun.

21 Oct 2008

Beta-blockers raise the risk of a heart attack after surgery

A new study has found that for some patients undergoing surgery, beta-blockers before and around the time of the operation increases their risk of heart attack and death.

21 Oct 2008

Junk food responsible for 35% of the world's heart attacks

New research by Canadian scientists says junk food causes a third of all heart attacks and it is diets heavy in fried foods, salty snacks and meat which are the culprits.

21 Oct 2008

Fatty acids may be the culprit in Alzheimer's

According to new research from the U.S. controlling the level of a fatty acid in the brain could help treat Alzheimer's disease (AD).

21 Oct 2008

Gene could 'knock the sox' off cancer!

Australian scientists from the Institute for Molecular Bioscience at The University of Queensland (UQ), have identified a gene which could very well 'knock the sox' off cancer and lymphatic disorders.

21 Oct 2008

Contact lenses are home to pathogenic amoebae

Contact lenses increase the risk of infection with pathogenic protozoa that can cause blindness. New research, published in the November issue of the Journal of Medical Microbiology, shows that a high percentage of contact lens cases in Tenerife are contaminated with Acanthamoeba that cannot be killed by normal contact lens solution.

20 Oct 2008

Getting to grips with the complexity of disease proteins

Drug molecules seldom act simply on one protein but on protein complexes and networks. A deeper understanding of these 'cooperative assemblies' should lead to better targeting of drugs.

20 Oct 2008

Sun-damaged skin responds well to laser treatment

Researchers at the University of Michigan Health System Department of Dermatology have found scientific evidence that the appearance of sun-damaged skin may be improved by treatment with a topical product that increases the skin's sensitivity to light, followed by laser therapy.

20 Oct 2008

Targeted cell delivery to the cervical spinal cord is a promising strategy to slow loss of motor neurons in ALS

In a disease like ALS - one that's always fatal and that has a long history of research-resistant biology - finding a proof of principle in animal models is significant.

20 Oct 2008

Chronic disease keeping older Australians out of the workforce

Chronic diseases such as diabetes and arthritis may be keeping more than 660,000 older Australians out of the workforce, Sydney University academics have found.

20 Oct 2008

Chance of dying from cancer before the age of 84 is falling

The chance of dying from cancer before the age of 84 is becoming much smaller for most types of cancer and should continue falling over the next 20 years according to a new study from Cancer Research UK.

19 Oct 2008

Molecule stops DNA replication in its tracks

When a dividing cell duplicates its genetic material, a molecular machine called a sliding clamp travels along the DNA double helix, tethering the proteins that perform the replication.

19 Oct 2008

Depression and suicidal thoughts among police officers differ based on gender and work shift

A quarter of female police officers and nearly as many male officers assigned to shift work had thought about taking their own lives, a new study of police work patterns and stress headed by a University at Buffalo researcher has shown.

19 Oct 2008

Genes that control cell death may play role in age-related hearing loss

Several genes that play a role in how our body's cells normally auto-destruct may play a role in age-related hearing loss, according to research published online in the journal Apoptosis - a journal devoted to the topic of cell suicide, or programmed cell death.

19 Oct 2008

Waste from gut bacteria helps host control weight

A single molecule in the intestinal wall, activated by the waste products from gut bacteria, plays a large role in controlling whether the host animals are lean or fatty, a research team, including scientists from UT Southwestern Medical Center, has found in a mouse study.

19 Oct 2008

Brain-derived neurotrophic factor may predict schizophrenia relapse

A factor that helps optimize brain formation and function may also provide clues about whether patients suffering with schizophrenia are headed toward relapse, researchers say.

16 Oct 2008

White wine as healthy for the heart as red

A new study will provide comfort to white wine lovers and give them a good excuse to pour themselves a glass of Sauvignon blanc because it now appears that white wine is just as healthy for the heart as red.

16 Oct 2008

New therapy for heart failure

During heart failure the body reacts to the production of the hormone aldosterone. Too much aldosterone can stiffen and damage the muscles of the heart.

15 Oct 2008

Model against unnecessary use of antibiotics

Patients in intensive care units (ICU) are often administered antibiotics against ventilator-associated pneumonia, 'to be on the safe side'. Dutch researcher Stefan Visscher has developed a model that can quickly establish whether or not a patient has pneumonia. This can prevent unnecessary treatment with antibiotics.

15 Oct 2008