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Alcohol and drug misuse fuels Scottish suicide and homicide rates

Alcohol and drug misuse mean Scots are almost twice as likely to kill or take their own life compared to people living in England and Wales, research published Monday, June 16 reveals.

From The University of Manchester 16 Jun 2008

HIPAA Privacy Rule is having a negative impact on the advance of biomedical research

The privacy rule of the Health Insurance Portability and Accountability Act (HIPAA) is having a negative impact on the advance of biomedical research and the search for treatments that benefit society, says a newly-released report by the Association of Academic Health Centers (AAHC).

16 Jun 2008

Unique brain maps to assist surgery and research

Researchers from the Howard Florey Institute in Melbourne are developing new technology to create individualised brain maps that will revolutionise diagnosis of disease and enhance the accuracy of brain surgery.

16 Jun 2008

New research scotches link between heroin drought and increased amphetamine use

The suspicion on the part of some experts that Australia's heroin drought has led to an increase in amphetamine use in the last decade, has been scotched by the latest research from the New South Wales Bureau of Crime Statistics and Research.

16 Jun 2008

Pomegranate extract may provide humans with relief of chronic inflammatory conditions

Oral ingestion of pomegranate extract reduces the production of chemicals that cause inflammation suggests a study published in BioMed Central's open access Journal of Inflammation. The findings indicate that pomegranate extract may provide humans with relief of chronic inflammatory conditions.

15 Jun 2008

How to reduce obesity and cardiovascular disease risk

Changes in society are leading to a sedentary lifestyle and are causing a rise in the number of people with obesity and cardiovascular disease. This is consequently having a large impact on the health of the nation.

15 Jun 2008

Transfer of learning traced to areas of the brain

Practice makes perfect, but a question that still remains a mystery is why it is so difficult to transfer learning from a trained to an untrained task? Why are we no better at remembering faces when we have been training our memory for words? Scientists at Umea University and Karolinska Institutet in Sweden now show in the journal Science that the answer lies in the brain areas activated by each task.

15 Jun 2008

Nanoparticles trigger built-in cell-death signal to overcome drug resistance

One of the most vexing problems in treating cancer is the propensity of tumors to develop resistance to a wide range of anticancer drugs. Over 70 percent of ovarian cancer patients, for example, have drug-resistant tumors at the time of their initial diagnosis, and virtually all patients who relapse have drug-resistant tumors.

15 Jun 2008

High-content screening as a universal tool for fingerprinting of vytotoxicity of nanoparticles

As researchers develop an ever-expanding toolkit of nanoparticles for use as drug and imaging agent delivery vehicles, there is a growing need to understand how a given nanoparticle's physical and chemical properties affect biological activity and toxicity.

15 Jun 2008

Nanoparticle delivers antisense agent to tumors

A multifunctional drug delivery system consisting of a lipid-based nanoparticle, a standard anticancer drug, and a short nucleic acid designed to augment the activity of that drug has demonstrated the ability to treat drug-resistant tumor cells.

15 Jun 2008

Human tumor nanoparticles induce apoptosis of pancreatic cancer cells

Using nanoparticles made from pieces of tumor cells, investigators from Aix-Marseille University in Marseille, France, have developed a new type of anticancer agent that appears to stop tumor cell growth and proliferation.

15 Jun 2008

Discovery of mechanism that prevents cells from transforming into cancer cells

MRC scientists have discovered a mechanism that prevents cells from transforming into cancer cells. As cells age they enter a state called senescence, a kind of suspended animation that allows a cell to keep functioning but prevents it from changing. This state can also be triggered by what's called an 'insult' to the cell, for example a signal from a cancer-initiating gene.

15 Jun 2008

New technique provides greater understanding of how drugs get in and out of cells in our bodies

A team led by female scientists at the Universities of Bristol and Cambridge has developed an exciting new technique which may lead to a greater understanding of how drugs get in and out of the cells in our bodies. The method identifies the structures that guard the entrance and exits to cells.

15 Jun 2008

Scientists identify molecular trick that may explain part of Salmonella's fierceness

Salmonella is serving up a surprise not only for tomato lovers around the country but also for scientists who study the rod-shaped bacterium that causes misery for millions of people.

15 Jun 2008

UT Southwestern investigators test groundbreaking depression research in real-world setting

UT Southwestern Medical Center psychiatry researchers have taken what they learned from their groundbreaking research on treating depression and are applying it to real-world clinical settings.

15 Jun 2008

Industry supports international melanoma research

Provectus Pharmaceuticals and the Australia and New Zealand Melanoma Trials Group (ANZMTG) have joined forces to advance cutting edge melanoma research at the University of Sydney.

15 Jun 2008

Researchers find gamma-secretase modulators being tested for Alzheimer’s work in unexpected and beneficial ways

Researchers at Mayo Clinic, with their national and international collaborators, have discovered how a class of agents now in testing to treat Alzheimer's disease work, and say they may open up an avenue of drug discovery for this disease and others.

11 Jun 2008

Smad proteins regulate microRNA processing

Researchers at Tufts University School of Medicine and Tufts Medical Center have found that Smad proteins regulate microRNA (miRNA) processing.

11 Jun 2008

Discovery of gene linked to adult-onset obesity

Researchers at the University of Minnesota have discovered a gene that may provide a clue as to why obesity rates increase with age. The research was published today in the Proceedings of the National Academy of Sciences.

11 Jun 2008

Vitamin D, "the heart tranquilizer"

Strong bones, a healthy immune system, protection against some types of cancer: Recent studies suggest there's yet another item for the expanding list of vitamin D benefits. Vitamin D, "the sunshine vitamin," keeps the heart, the body's long-distance runner, fit for life's demands.

11 Jun 2008