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Search for the 'on' switches may reveal genetic role in development and disease

A new resource that identifies regions of the human genome that regulate gene expression may help scientists learn about and develop treatments for a number of human diseases, according to researchers at Duke's Institute for Genome Sciences & Policy (IGSP).

25 Jan 2008

Researchers unravel mystery of cell division

Experts in mitosis (cell division) at the University of Virginia Health System have made discoveries that explain how one protein the kinase Aurora B could have such a large role in guiding and policing the process of cell division.

25 Jan 2008

Protein that controls hair growth also keeps stem cells slumbering

Like fine china and crystal, which tend to be used sparingly, stem cells divide infrequently.

25 Jan 2008

New approach to detect autism earlier

A new way of understanding autistic disorders, incorporating both psychological and biological factors, could lead to the conditions being picked up earlier, research from UNSW has found.

25 Jan 2008

Mental and physical stimulation delays dementia in Huntington's disease

Scientists at Melbourne's Howard Florey Institute have discovered that mental and physical stimulation delays the onset of dementia in the fatal genetic disease, Huntington's disease.

25 Jan 2008

Improved diagnosis of cutaneous leishmaniasis thanks to new techniques

Cutaneous leishmaniasis (CL) is a non-lethal disease but can have grave consequences for the patient.

25 Jan 2008

Researchers identify five genes with possible protective capabilities against a Parkinson's disease trait

University of Alabama researchers have identified five genes within animal models displaying protective capabilities against a hallmark trait of Parkinson's disease.

25 Jan 2008

Evolutionary 'battle scars' identify enhanced antiviral activity

Rapid evolution of a protein produced by an immunity gene is associated with increased antiviral activity in humans, a finding that suggests evolutionary biology and virology together can accelerate the discovery of viral-defense mechanisms, according to researchers at Fred Hutchinson Cancer Research Center.

25 Jan 2008

Elusive pancreatic stem cells found in adult mice

Just as many scientists had given up the search, researchers have discovered that the pancreas does indeed harbor stem cells with the capacity to generate new insulin-producing beta cells.

25 Jan 2008

Could the pursuit of happiness go too far?

Could the pursuit of happiness go too far? Most self-help books on the subject offer tips on how to maximize one's bliss, but a new study suggests that moderate happiness may be preferable to full-fledged elation.

25 Jan 2008

Deficient regulators in the immune system responsible for type 1 diabetes

The main regulators of the immune system, called CD4+Treg cells, are thought to be highly involved in a large range of immune diseases.

25 Jan 2008

Building stronger bones, one stem cell at a time

Mesenchymal stem cells (MSCs) are bone marrow-derived cells that are capable of giving rise to various cell types through a process known as differentiation.

25 Jan 2008

New approach to gene therapy

RNA interference (RNAi) represents an innovative new strategy for using small RNA molecules to silence specific genes associated with disease processes, and a series of review articles describing the state-of-the-art and potential therapeutic applications of RNAi and microRNAs will begin with two review papers in the January 2008 issue (Volume 19, Number 1) of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc.

24 Jan 2008

Researchers identify brain's 'eureka' circuitry

Researchers have found the brain region that controls the decision to halt your midnight exploration of the refrigerator and commence enjoyment of that leftover chicken leg.

24 Jan 2008

No clear evidence that antidepressants assist in the management of chronic low back pain

Doctors commonly prescribe antidepressants for patients with low back pain for three main reasons; to relieve pain; reduce mild depression and improve a person's mood; and improve sleep.

24 Jan 2008

Nitrogen fixation process in plants to combat drought in various species of legumes

The regulation of the biological fixation of nitrogen in hydric stress conditions varies with the different species of legume plants studied.

24 Jan 2008

New method enables design, production of extremely novel drugs

A new chemical synthesis method based on a catalyst worth many times the price of gold and providing a far more efficient and economical method than traditional ones for designing and manufacturing extremely novel pharmaceutical compounds is described by its University at Buffalo developers in a review article in the current issue of Nature.

24 Jan 2008