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New model system may better explain regulation of body weight

A new mathematical model of the physiological regulation of body weight suggests a potential mechanism underlying the difficulty of losing weight, one that includes aspects of two competing hypotheses of weight regulation.

15 Jan 2009

New drug shows promise for phenylketonuria

PKU is described by scientists as an autosomal recessive genetic disease that is characterized by a deficiency in an enzyme called phenylalanine hydroxylase (PAH).

15 Jan 2009

Most support Alzheimer's research based on family consent

By the time they have been diagnosed with Alzheimer's disease, many patients' decision-making ability is so impaired that they cannot give informed consent to participate in research studies.

15 Jan 2009

Midlife caffeine intake lowers risk of late-life dementia

Midlife coffee drinking can decrease the risk of dementia/Alzheimer's disease (AD) later in life.

15 Jan 2009

Half of people 50 years and younger with low 10-year risk of CVD have high lifetime risk

About half of people 50 years and younger who have a low 10-year or short-term cardiovascular disease (CVD) risk may have a high lifetime risk, researchers report in Circulation: Journal of the American Heart Association.

15 Jan 2009

Discovery of link between genetic defect on chromosome 15 and epilepsy

In a research published in the advanced online publication of the scientific magazine Nature Genetics, researchers have identified a genetic defect for common epilepsies on chromosome 15.

15 Jan 2009

Researchers study asymmetry in the brain

A tug-of-war between the two sides of the brain causes it to become asymmetrical, according to research published today in the journal Neuron.

15 Jan 2009

Discovery of protein that amplifies cell death

Scientists at Albert Einstein College of Medicine of Yeshiva University have identified a small intracellular protein that helps cells commit suicide.

15 Jan 2009

Strong relationship between our health as adults and our early diet

If you have trouble keeping weight off and you're wondering why - the surprising answer may well be the cheeseburgers you ate - when you were a toddler.

15 Jan 2009

New research reveals brain activity that underlies our tendency to "follow the crowd"

The study, published by Cell Press in the January 15th issue of the journal Neuron, provides intriguing insight into how human behavior can be guided by the perceived behavior of other individuals.

15 Jan 2009

Important relationship between fetal and adolescent alcohol experiences

Rats whose mothers were fed alcohol during pregnancy are more attracted to the smell of liquor during puberty.

15 Jan 2009

Treadmill exercise improves walking endurance for patients with PAD

Patients with peripheral arterial disease (PAD), which can include symptoms such as pain in the legs, who participated in supervised treadmill exercise improved their walking endurance and quality of life, according to a study in the January 14 issue of JAMA.

14 Jan 2009

Transplanted fatty livers associated with worse prognosis for patients with hepatitis C

A new study suggests that patients with hepatitis C (HCV) who need a liver transplant should not receive an organ with high levels of fatty deposits (a.k.a. hepatic steatosis).

14 Jan 2009

Time of day influences response to chemotherapy

For years, research has hinted that the time of day that cancer patients receive chemotherapy can impact their chances of survival.

14 Jan 2009

Influenza vaccine helps 50-64 year olds stay at work

Workers age 50-64 who received influenza vaccine lost substantially fewer days of work and worked fewer days while ill, according to a new study in the Feb. 1 issue of Clinical Infectious Diseases , now available online.

14 Jan 2009

Study looks at how pre-existing mental health conditions affect outcomes in foster care

Of the approximately half-million children and adolescents in foster care in the U.S., experts estimate that 42 to 60 percent of them have emotional and behavioral problems.

14 Jan 2009

Discovery of potential biomarker for smoking-related lung diseases

Researchers from Boston University School of Medicine (BUSM) have demonstrated that a recently discovered class of molecule called microRNA (miRNAs), regulate the gene expression changes in airway cells that occur with smoking and lung cancer.

13 Jan 2009

New folate antagonists selectively target pathway important in rheumatoid arthritis

Methotrexate (MTX), a folate antagonist that blocks folic acid activity, is the most widely used disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis.

13 Jan 2009

Numerical analysis estimates numbers of older US adults who may benefit from statin therapy

Researchers estimate more than 11 million older Americans may be newly eligible for statin therapy if findings from a recently published large clinical trial are adopted into clinical practice guidelines, according to a new analysis of the trial data.

13 Jan 2009

Cell phone use not linked to melanoma of the eye

Mobile phone use is not associated with the risk of melanoma of the eye, researchers report in the January 13 online issue of the Journal of the National Cancer Institute.

13 Jan 2009