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Getting to grips with the complexity of disease proteins

Drug molecules seldom act simply on one protein but on protein complexes and networks. A deeper understanding of these 'cooperative assemblies' should lead to better targeting of drugs.

20 Oct 2008

Sun-damaged skin responds well to laser treatment

Researchers at the University of Michigan Health System Department of Dermatology have found scientific evidence that the appearance of sun-damaged skin may be improved by treatment with a topical product that increases the skin's sensitivity to light, followed by laser therapy.

20 Oct 2008

Targeted cell delivery to the cervical spinal cord is a promising strategy to slow loss of motor neurons in ALS

In a disease like ALS - one that's always fatal and that has a long history of research-resistant biology - finding a proof of principle in animal models is significant.

20 Oct 2008

Chronic disease keeping older Australians out of the workforce

Chronic diseases such as diabetes and arthritis may be keeping more than 660,000 older Australians out of the workforce, Sydney University academics have found.

20 Oct 2008

Chance of dying from cancer before the age of 84 is falling

The chance of dying from cancer before the age of 84 is becoming much smaller for most types of cancer and should continue falling over the next 20 years according to a new study from Cancer Research UK.

19 Oct 2008

Molecule stops DNA replication in its tracks

When a dividing cell duplicates its genetic material, a molecular machine called a sliding clamp travels along the DNA double helix, tethering the proteins that perform the replication.

19 Oct 2008

Depression and suicidal thoughts among police officers differ based on gender and work shift

A quarter of female police officers and nearly as many male officers assigned to shift work had thought about taking their own lives, a new study of police work patterns and stress headed by a University at Buffalo researcher has shown.

19 Oct 2008

Genes that control cell death may play role in age-related hearing loss

Several genes that play a role in how our body's cells normally auto-destruct may play a role in age-related hearing loss, according to research published online in the journal Apoptosis - a journal devoted to the topic of cell suicide, or programmed cell death.

19 Oct 2008

Waste from gut bacteria helps host control weight

A single molecule in the intestinal wall, activated by the waste products from gut bacteria, plays a large role in controlling whether the host animals are lean or fatty, a research team, including scientists from UT Southwestern Medical Center, has found in a mouse study.

19 Oct 2008

Brain-derived neurotrophic factor may predict schizophrenia relapse

A factor that helps optimize brain formation and function may also provide clues about whether patients suffering with schizophrenia are headed toward relapse, researchers say.

16 Oct 2008

White wine as healthy for the heart as red

A new study will provide comfort to white wine lovers and give them a good excuse to pour themselves a glass of Sauvignon blanc because it now appears that white wine is just as healthy for the heart as red.

16 Oct 2008

New therapy for heart failure

During heart failure the body reacts to the production of the hormone aldosterone. Too much aldosterone can stiffen and damage the muscles of the heart.

15 Oct 2008

Model against unnecessary use of antibiotics

Patients in intensive care units (ICU) are often administered antibiotics against ventilator-associated pneumonia, 'to be on the safe side'. Dutch researcher Stefan Visscher has developed a model that can quickly establish whether or not a patient has pneumonia. This can prevent unnecessary treatment with antibiotics.

15 Oct 2008

Prolonging the withdrawal of life support in the ICU affects family satisfaction with care

Clinicians in the intensive care unit (ICU) often care for patients who are on several life support measures at once. When such a patient is dying and the decision is reached to withdraw life support, these clinicians may make an imperfect compromise in seeking to balance the complex needs of the patient and the patient's family - they may remove the life support measures one at a time over a period of days, rather than withdrawing all at once.

15 Oct 2008

Artificial brain-muscle connections used to restore movement to paralyzed limbs

Researchers in a study funded by the National Institutes of Health (NIH) have demonstrated for the first time that a direct artificial connection from the brain to muscles can restore voluntary movement in monkeys whose arms have been temporarily anesthetized. The results may have promising implications for the quarter of a million Americans affected by spinal cord injuries and thousands of others with paralyzing neurological diseases, although clinical applications are years away.

15 Oct 2008

Alcohol linked to brain shrinkage

According to the latest research drinking alcohol shrinks the brain and the more alcohol an individual drinks, the smaller his or her total brain volume will be.

15 Oct 2008

Study reveals too many people have faecal bacteria on their hands

According to a preliminary study conducted by the research team, the further north you go in Britain, the more likely you are to have faecal bacteria on your hands, and men were the worse offenders.

14 Oct 2008

Shark antibodies show potential as lifesaver from cancer

Australian scientists have discovered a potentially potent weapon in the fight against cancer in antibodies taken from shark blood.

14 Oct 2008

Combo of sunlight and low antioxidant levels leave seniors at risk of eye disease

European research has revealed that blue light exposure from the sun combined with low plasma levels of antioxidants may contribute to certain forms of the eye disease age-related macular degeneration (AMD).

14 Oct 2008

Resveratrol shows promise for treating human alcoholic fatty liver disease

The accumulation of fat in the liver as a result of chronic alcohol consumption could be prevented by consuming resveratrol, according to a new study with mice. The research found that resveratrol reduced the amount of fat produced in the liver of mice fed alcohol and, at the same time, increased the rate at which fat within the liver is broken down.

14 Oct 2008