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Scientists decipher a signaling pathway crucially involved in Crohn's disease and ulcerative colitis

Inflammatory bowel diseases, such as Crohn's disease and Ulcerative Colitis, severely impair the lives of more than four million people worldwide. The development of effective therapies against these diseases requires an understanding of their underlying molecular mechanisms.

15 Mar 2007

Generalist genes responsible for a wide range of learning disorders

According to a review in the premier issue of Mind, Brain, and Education, the latest research into learning disabilities suggests that 'generalist' genes are responsible for a wide range of learning disorders.

15 Mar 2007

Protein duo maintains communication among nerves

Frustration gave way to satisfaction when an experiment that seemed to foil St. Jude researchers actually brought them a step closer to understanding how the brain maintains healthy lines of communications among its nerves.

15 Mar 2007

Researchers use poliovirus to destroy neuroblastoma tumors in mice

The cause of one notorious childhood disease, poliovirus, could be used to treat the ongoing threat of another childhood disease, neuroblastoma.

15 Mar 2007

New anti-cancer target in enzyme MAP4K3

Scientists working at the Institute for Cancer Research have found a new anti-cancer target in MAP4K3, an enzyme which is able to 'switch on' the growth-promoter mTOR.

14 Mar 2007

Discovery of new cell involved with cancer

Scientists have discovered a new type of cell that appears to play a role in the development of cancer – a highly volatile, precancerous stem cell that can either remain benign or become malignant, depending upon environmental cues.

14 Mar 2007

Arsenic in drinking water can lead to miscarriages and sudden infant death

For the first time, researchers have been able to show that mothers who drink water containing arsenic run an increased risk of having a miscarriage or losing their child in its first year. This has been demonstrated by a research team from Sweden and Bangladesh in an article published last Saturday in the Net edition of American Journal of Epidemiology.

14 Mar 2007

Researchers uncover genetic sequence responsible for rare form of pancreatic cancer

Pancreatic ductal adenocarcinoma is an almost uniformly fatal disease regardless of the stage at time of diagnosis. However, a small percentage of patients develop a form of ductal adenocarcinoma associated with cystic lesions that can be detected earlier, is less aggressive and has a 50 percent long-term survival rate.

14 Mar 2007

Chemical cues turn embryonic stem cells into cerebellar neurons

Embryonic stem cells have shown a great deal of promise for alleviating heart disease and regenerating organs. But for some of the conditions for which people hold out the most hope - Alzheimer's and Parkinson's, for example - there's been little evidence to date that stem cells can work.

14 Mar 2007

Crocodiles provide clues to new pain treatments for humans

Sydney University researchers have identified how crocodiles and other reptiles detect temperature - shedding new light on their adaptation to environmental changes and pointing to new pain treatments for humans.

14 Mar 2007

Interferon gamma identified as one of the signaling proteins involved with tumor relapse

Researchers at Virginia Commonwealth University's Massey Cancer Center studying the interaction between the immune system and cancer cells have identified interferon gamma as one of the signaling proteins involved with tumor relapse.

13 Mar 2007

Gene and a region of a chromosome identified that may lead to autism in children

Yale School of Medicine autism experts Fred Volkmar, M.D. and Ami Klin are part of a global research consortium from 19 countries to identify a gene and a region of a chromosome that may lead to autism in children.

13 Mar 2007

Novel pathway for antibiotic-induced cell death

Scientists have identified unforeseen mechanisms by which quinolones - a family of broad-spectrum antibiotics among the most widely prescribed - induce bacterial cell death.

13 Mar 2007

Date fighting associated with other health risk behaviors

College students who participate in date fighting are more likely to drink alcohol and engage in other health risk behaviors, according to a pediatric researcher at Brenner Children's Hospital, part of Wake Forest University Baptist Medical Center.

13 Mar 2007

Using a light hand to treat Hodgkin disease

Children with low-risk Hodgkin disease can be cured using cancer drugs that have only minimal or no toxicity, combined with low doses of radiation, according to St. Jude researchers.

13 Mar 2007

Disorderly protein brings order to cell division

The secret to the ability of a molecule critical for cell division to throw off the protein yoke that restrains its activity is the yoke itself - a disorderly molecule that seems to have a mind of its own, say investigators at St. Jude

13 Mar 2007

New method for identifying viruses and bacteria that cause common infections in children

Infectious disease specialists at UT Southwestern Medical Center have found a new method for identifying suspect viruses and bacteria that cause some of the most common acute infections in children.

13 Mar 2007

Does having longer legs really make a difference?

Scientists have known for years that the energy cost of walking and running is related primarily to the work done by muscles to lift and move the limbs.

12 Mar 2007

$20 million boosts AIDS treatment, vaccine research in Rochester

The University of Rochester Medical Center will continue to play a leading role in the nation’s effort fighting AIDS, with more than $20 million to be directed to Rochester doctors and researchers who are working on new treatments for the disease and on finding a vaccine to prevent it altogether, Federal officials announced today.

12 Mar 2007