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Gene expression signature associated with survival in advanced ovarian cancer

A new study published this week in the open-access journal PLoS Medicine identifies molecular pathways associated with outcomes in ovarian cancer.

2 Feb 2009

Genetic change prevents cell death in mouse model of Parkinson's disease

By shifting a normal protective mechanism into overdrive, a University of Wisconsin-Madison scientist has completely shielded mice from a toxic chemical that would otherwise cause Parkinson's disease.

2 Feb 2009

Fibroblasts invade at a snail's pace

A transcription factor known to drive the formation of fibroblasts during development also promotes their ability to invade and remodel surrounding tissues, report Rowe et al. in the February 9, 2009 issue of the Journal of Cell Biology.

2 Feb 2009

After knee replacement exercise is crucial

It may be uncomfortable at first, but doing exercises to strengthen your quadriceps after you've had knee replacement surgery due to osteoarthritis is critical to your recovery.

2 Feb 2009

Even with medication, asthma patients show chronic airflow changes in lungs

Using a special MRI technique, researchers have determined that the location and degree of airway narrowing in the lungs of asthma sufferers can be markedly persistent over time.

2 Feb 2009

Education may not affect how fast you will lose your memory

While a higher level of education may help lower the risk of Alzheimer's disease, new research shows that once educated people start to become forgetful, a higher level of education does not appear to protect against how fast they will lose their memory.

2 Feb 2009

Study looks at effects of 9/11 attacks on drink driving

The September 11 terrorist attacks had a profound impact on this country's psyche.

2 Feb 2009

Discovery fleshes out metabolism of key environmental and energy bacteria

An international collaboration of researchers has discovered a new enzyme in a species of bacteria with potential environmental cleanup and energy roles.

2 Feb 2009

Differences in recovered memories of childhood sexual abuse

When a child experiences a traumatic event, such as sexual abuse, it may not be until well into adulthood that they remember the incident.

2 Feb 2009

New genetic clues on molecular evolution of Q fever pathogen

Scientists from the National Institute of Allergy and Infectious Diseases, Texas A&M Health Center, and the Virginia Bioinformatics Institute at Virginia Tech have uncovered genetic clues about why some strains of the pathogen Coxiella burnetii are more virulent than others.

2 Feb 2009

Cell-building discovery offers great potential for basic cell biology, drug and tissue research

Brown University biomedical engineers can now grow and assemble living microtissues into complex three-dimensional structures in a way that will advance the field of tissue engineering and may eventually reduce the need for certain kinds of animal research.

2 Feb 2009

New way to fight off bacteria

Whenever humans create a new antibiotic, deadly bacteria can counter it by turning into new, indestructible super-bugs.

2 Feb 2009

Distrust of medical research more common among African American parents

Distrust of medical research appears more common among African American parents than white parents and may present a barrier to enrollment of minority children in research studies, according to a report in the February issue of Archives of Pediatrics & Adolescent Medicine.

2 Feb 2009

Shortened gene region linked to breast cancer

Reza Zarnegar and colleagues, at the University of Pittsburgh, Pittsburgh, have determined that genetic variation in a piece of DNA that regulates activity of the HGF gene might be a useful marker to identify individuals with an increased risk of developing breast cancer.

2 Feb 2009

New potential targets for colitis-associated cancer

Recent research from the laboratory of Michael Karin, PhD, at the University of California, San Diego School of Medicine - the first researcher to demonstrate a molecular link between inflammation and cancer - has identified two potential targets for the prevention and treatment of colitis-associated cancer (CAC), the most serious complication of inflammatory bowel disease.

2 Feb 2009

BioGenes as new designated partner in EU funded dementia project

BioGenes GmbH, a specialist in sophisticated antibody development, has been chosen as a new partner of cNEUPRO. cNEUPRO is a EU funded research project to analyse neurodegenerative diseases and discover novel biomarkers, and so improve early and differential diagnosis of Alzheimer's dementia.

2 Feb 2009