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Epigenomic test that could improve treatment for specific gastric cancers

A study by researchers at the John Wayne Cancer Institute at Saint John's Health Center in a recent issue of Journal of Clinical Oncology identifies activation of the enzyme COX-2 in gastric cancer tumors as a prognostic indicator for poor outcome.

12 Dec 2007

Red meat and cancer

New findings provide evidence that people who eat a lot of red and processed meats have greater risk of developing bowel and lung cancer than people who eat small quantities.

12 Dec 2007

Cancer cell line developed that is resistant to new cancer therapy

A cancer cell line that is resistant to one of the newest classes of cancer treatments has been developed by researchers who already are using it to determine what else to give patients when this happens.

12 Dec 2007

Addition of antibiotics to MS therapy could slow down progression of the disease

Researchers from Louisiana State University in the U.S. are suggesting that the addition of antibiotics to standard drug therapy for multiple sclerosis, may slow down the progress of the disease.

11 Dec 2007

Waterborne carbon increases threat of environmental mercury

Mercury is a potent neurotoxin and a worrisome environmental contaminant, but the severity of its threat appears to depend on what else is in the water.

10 Dec 2007

New model for neurodegeneration

The gradual loss of dopamine neurons is a hallmark of many neurodegenerative diseases - Parkinson's Disease chief among them.

10 Dec 2007

Need for education for primary care physicians on rarely seen cancers

Many primary care physicians may lack the necessary knowledge when it comes to recognizing the signs, symptoms and making proper diagnoses in cases of blood cancers such as leukemia and lymphoma, a recent survey indicates.

10 Dec 2007

Silencing small but mighty cancer inhibitors

Researchers from Johns Hopkins and the University of Pennsylvania have uncovered another reason why one of the most commonly activated proteins in cancer is in fact so dangerous.

10 Dec 2007

Researchers uncover delicate protein balance behind the immune system response

A team of researchers from the University of Pennsylvania School of Veterinary Medicine has identified the protein interactions involved in the immune system process that fights infection yet, in certain inflammatory diseases, runs amok and attacks friendly tissue.

10 Dec 2007

Physicians seek strategies to improve the quality of sleep in ICU

The sleep patterns of patients in the intensive care unit are so superficial that they barely spend any time in the restorative stages of sleep that aid in healing, UT Southwestern Medical Center physicians have found.

10 Dec 2007

New test for targeted therapy in acute myeloid leukemia

Oregon Health & Science University Cancer Institute researcher Jeff Tyner, Ph.D., has created a way to identify proteins that are candidates for targeted therapy in acute myeloid leukemia using an assay that yields results in just four days.

10 Dec 2007

New therapeutic options for newly diagnosed multiple myeloma patients

Mayo Clinic researchers presented results of a phase II trial of myeloma induction therapy -- a first step therapy designed to reduce cancer cells numbers -- with cyclophosphamide, bortezomib, and dexamethasone (Cybor-D) showing an improved response over the traditional lenalidomide-dexamethasone (L-Dex) therapy.

10 Dec 2007

New technique reveals insights into lung disease

Doctors at the Universities of Leicester and Nottingham are collaborating to use a magnetic resonance technique to image and quantify the air spaces inside the lungs.

10 Dec 2007

Most adults with conditions that increase cardiovascular disease risk have hypertension

Nearly three-fourths of American adults with conditions such as coronary heart disease, stroke, diabetes or others that raise their risk for cardiovascular complications also have hypertension (high blood pressure), according to a report in the December 10/24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

10 Dec 2007

Missing protein provides clue to ovarian cancer drug success

Scientists have discovered a protein which could improve the success rate of the tumour shrinking drug paclitaxel, in the treatment of ovarian cancer, a study reveals in Cancer Cell.

10 Dec 2007

Lipids in the brain an important factor for Alzheimer's disease

As the most common form of dementia in the Western world, Alzheimer's disease carries enormous implications for our ageing society.

10 Dec 2007

Keeping at-risk cells from developing cancer

Researchers at Johns Hopkins have discovered that cancers arising from epigenetic changes - in this case the inappropriate activation of a normally silent gene - develop by becoming addicted to certain growth factors.

10 Dec 2007

International team gets new award to research the causes of bladder problems that affect one in six adults

An international research project which aims to solve why some people feel the constant need to urinate - a condition that affects one in every six adults - has received a prestigious new £420,000 award from the leading UK-based urology journal and charity BJU International.

10 Dec 2007

Is there a developmental component to the risk for depression?

Psychiatrists remain divided as to how to define and classify the mood and anxiety disorders, the most common mental disorders.

10 Dec 2007

Growth factor receptor affects prostate cancer progression

Breeding mice with a gene for a cellular receptor that can be turned on and off-at will-not only enabled researchers at Baylor College of Medicine in Houston to show how prostate cancer progresses, but also provides a model for studying when a drug targeting a gene will have an effect on the cancer.

10 Dec 2007