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Rosiglitazone and Pioglitazone increase risk of congestive heart failure but not the risk of cardiovascular death

Patients with type 2 diabetes* or prediabetes* are more likely to develop congestive heart failure (CHF) when given rosiglitazone or pioglitazone, as compared with controls. However these drugs did not increase the risk of cardiovascular death (CVD) for these patients.

1 Oct 2007

Researchers discover one of the mechanisms that prevents the spread of colon cancer

The first step in the development of colon cancer is the formation of benign tumours, called adenomas, in the intestine. Over time, these tumours may progress to produce colon cancer if they undergo a series of mutations and genetic alterations.

1 Oct 2007

New way to deliver agents for the treatment of skin cancer

Queen's University scientists have hit upon a revolutionary way to deliver agents for the treatment of skin cancer.

1 Oct 2007

Hearts are experts at self-preservation

Bristol researchers have identified a heart protection mechanism in mice that surgeons and cardiologists may be able to exploit to improve treatments for patients in future.

1 Oct 2007

microRNAs may be key to HIV's ability to hide, evade drugs

Tiny pieces of genetic material called microRNA (miRNA), better known for its roles in cancer, could be a key to unlocking the secrets of how HIV, the AIDS virus, evades detection, hiding in the immune system.

1 Oct 2007

Gene that lowers cell stress could protect against Parkinson’s disease

The discovery of a relationship between two cell enzymes and their role in keeping the cell's energy generating machinery working smoothly could provide a new target for development of therapies for Parkinson's disease (PD).

1 Oct 2007

New Giardia lamblia research provides hope for millions of sufferers

Today's issue of the scientific journal Science presents research on the genetic make-up and biology of the parasite Giardia lamblia that ultimately may lead to better diagnosis and treatment of the diarrhea disease giardiasis, which affects 200 million people every year.

29 Sep 2007

New molecular evidence of the role of the hormone prolactin in breast cancer

They have found that prolactin, a pituitary hormone that normally stimulates breast development and milk production, initiates a new “signaling pathway” that may regulate the growth and survival of breast cancer cells.

29 Sep 2007

Simple tool improves communication between doctors and patients

A UCSF research team has developed a simple tool that can improve the effectiveness of communication between doctors and patients about prescribed medications and result in dramatic improvements in health and safety.

29 Sep 2007

Genomic profiling of lung tumors helps doctors choose most effective treatment

Determining the genetic profile of a particular lung tumor can help clinicians make the crucial decision about which chemotherapy treatment to try first.

29 Sep 2007

Females explain influence of past on future differently than males

A new study finds that young girls and women are more likely to believe that negative past events predict future events, compared to boys and men.

29 Sep 2007

Effects of good and bad carbohydrates

The latest common wisdom on carbohydrates claims that eating so-called "bad" carbohydrates will make you fat, but University of Virginia professor Glenn Gaesser says, "that's just nonsense."

29 Sep 2007

Research explains why opioids are thought to be ineffective in people with fibromyalgia

People who have the common chronic pain condition fibromyalgia often report that they don't respond to the types of medication that relieve other people's pain.

27 Sep 2007

Unmasked enzyme may lead to new drugs for type II diabetes

Scientists at the Medical Research Council have made a discovery that could pave the way for better treatments of type II diabetes.

27 Sep 2007

Hair reveals all!

Historically, hair has had a magical and almost cultic importance in human history and was, for instance, believed to be a source of power.

27 Sep 2007

30 percent of asthma in U.S.can be attributed to cat allergy

Researchers at the National Institutes of Health (NIH) have found that more than 50 percent of the current asthma cases in the country can be attributed to allergies, with approximately 30 percent of those cases attributed to cat allergy.

27 Sep 2007

Memory tasks require more coordinated brain blood flow for people with high blood pressure

Blood flow to the parts of the brain that support memory function differs between people with high blood pressure and those with normal blood pressure, and this difference seems to increase when high blood pressure is treated with medications, researchers reported today at the American Heart Association's 61st Annual Fall Conference of the Council for High Blood Pressure Research.

27 Sep 2007

Loss of TDP-43 gene found to be related to age-related neurological disorders

Researchers at Mayo Clinic in Jacksonville have discovered how loss of a gene can lead to accumulation of toxic proteins in the brain, resulting in a common dementia, and they say this mechanism may be important in a number of age-related neurological disorders.

27 Sep 2007

Many patients with diabetes say burden of care rivals complications of disease

Many patients with diabetes say that the inconvenience and discomfort of constant therapeutic vigilance, particularly multiple daily insulin injections, has as much impact on their quality of life as the burden of intermediate complications, researchers from the University of Chicago report in the October 2007 issue of Diabetes Care.

27 Sep 2007

Expertise modulates the perception of pain in others

Physicians apparently learn to “shut off” the portion of their brain that helps them appreciate the pain their patients experience while treating them and instead activate a portion of the brain connected with controlling emotions, according to new research using brain scans at the University of Chicago.

27 Sep 2007