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Notch protein helps human embryonic stem cells 'decide' their own fate

Researchers at Johns Hopkins have discovered that the Notch protein helps human embryonic stem cells 'decide' their own fate, a finding which may eventually be useful in programming cells for the development of stem cell therapies. Their results are reported in the May 2008 issue of Cell Stem Cell.

22 Jul 2008

Science of magic - understanding human cognition and perception

Magic tricks, like those by Derren Brown and David Blaine, should be studied more closely to gain a deeper knowledge of the way human beings think and act, according to research by British and Canadian psychologists.

22 Jul 2008

Discovery of cells for spinal-cord repair

A researcher at MIT's Picower Institute for Learning and Memory has pinpointed stem cells within the spinal cord that, if persuaded to differentiate into more healing cells and fewer scarring cells following an injury, may lead to a new, non-surgical treatment for debilitating spinal-cord injuries.

22 Jul 2008

Discovery of new anatomical path through which the brain and spleen communicate

In a major step in understanding how the nervous system and the immune system interact, scientists at The Feinstein Institute for Medical Research have identified a new anatomical path through which the brain and the spleen communicate.

21 Jul 2008

Suspect protein HMGB1 found to promote DNA repair, prevent cancer

An abundant chromosomal protein that binds to damaged DNA prevents cancer development by enhancing DNA repair, researchers at The University of Texas M. D. Anderson Cancer Center report online this week in the Proceedings of the National Academies of Science.

21 Jul 2008

Cranberry juice shows promise for urinary tract infections

For generations, people have consumed cranberry juice, convinced of its power to ward off urinary tract infections, though the exact mechanism of its action has not been well understood.

21 Jul 2008

Genetic mechanisms at play in blood cells important in Parkinson’s disease

What does the genetics of blood cells have to do with brain cells related to Parkinson's disease? From an unusual collaboration of neurologists and a pharmacologist comes the surprising answer: Genetic mechanisms at play in blood cells also control a gene and protein that cause Parkinson's disease.

21 Jul 2008

Gene expression test could help determine who needs more aggressive treatment

Researchers from four leading cancer centers have confirmed that an analysis involving a panel of genes can be used to predict which lung cancer patients will have the worst survival. The finding could one day lead to a test that would help determine who needs more aggressive treatment.

21 Jul 2008

Evolutionary back-and-forth for humans and viruses

For millennia, humans and viruses have been locked in an evolutionary back-and-forth - one changes to outsmart the other, prompting the second to change and outsmart the first.

21 Jul 2008

Regular meals important for the health

It is obvious to most people that our health is affected by what we eat; now, however, scientists have shown that it is also a matter of how often we eat.

21 Jul 2008

Oxytocin may inhibit social phobia

Swedish and British scientists have shown using functional magnetic resonance imaging (fMRI) that the hormone oxytocin can inhibit feelings of anxiety in specific individuals. Their discovery might lead to a better understanding and the improved treatment of psychiatric affections in which people feel distressed when meeting others, such as in cases of autism and social phobia.

20 Jul 2008

Fluoroquinolones can enhance gene-silencing tool

A way to turn off one gene at a time has earned acceptance in biology laboratories over the last decade. Doctors envision the technique, called RNA interference, as a tool to treat a variety of diseases if it can be adapted to humans.

20 Jul 2008

Obsessive compulsive disorder linked to activity in lateral orbitofrontal cortex

Cambridge researchers have discovered that measuring activity in a region of the brain could help to identify people at risk of developing obsessive compulsive disorder (OCD).

19 Jul 2008

Potentially new biomarkers for Alzheimer's

Every aging baby boomer listens for the footsteps of Alzheimer's, and for good reason: It's estimated that 10 million American boomers will develop the disease. The need to develop preventative strategies, ideally long before Alzheimer's destructive, clinical symptoms appear, is critical.

19 Jul 2008

Regular walking protects the Masai against cardiovascular disease

Scientists have long been puzzled by how the Masai can avoid cardiovascular disease despite having a diet rich in animal fats. Researchers at Karolinska Institutet believe that their secret is in their regular walking.

18 Jul 2008

Could arthritis wonder drugs provide clues for all disease?

Drugs that have helped treat millions of rheumatoid arthritis sufferers may hold the key to many more medical conditions, including atherosclerosis - a leading cause of heart disease - says the researcher who jointly invented and developed them.

From The University of Manchester 17 Jul 2008

Heart attack not a death sentence

Survivors of cardiac arrest who received intensive care can expect long-term quality of life at reasonable expense to the health care system.

17 Jul 2008

Standards in stem cell research

Standards in stem cell research help both scientists and regulators to manage uncertainty and the unknown, according to new research funded by the Economic and Social Research Council. Efforts to standardise practices across different labs is, however, a balancing act where the autonomy of scientists and fragility of living material need to be weighed against the need for comparable data.

17 Jul 2008

Gene variation increases risk of elevated triglycerides in Asians

A genetic variant found almost exclusively in individuals of Asian descent increases the risk of elevated triglycerides over four-fold, reports a comprehensive study in the August Journal of Lipid Research.

17 Jul 2008

Fred Hutchinson awarded $7.6 million to research how genetic variations influence risk of common diseases

Researchers at Fred Hutchinson Cancer Research Center have received a $7.6 million, four-year grant from the National Human Genome Research Institute to better understand the genetic and biological roots of common diseases. The Hutchinson Center is one of four U.S. research institutes to receive grants totaling about $31 million toward this effort.

17 Jul 2008