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Trauma a frequent experience on American Indian reservations

American Indians living on reservations are at high risk for being exposed to such trauma as witnessing a loved one's death or being the victim of a physical attack, according to research comparing trauma on two American Indian reservations to that in the general U.S. population.

27 Apr 2005

Natural glucose byproduct prevents brain damage and cognitive impairment after diabetic coma

A natural, non-toxic byproduct of glucose may prevent brain cell death and cognitive impairment in diabetics following an episode of severely low blood sugar, according to researchers at the San Francisco VA Medical Center (SFVAMC).

27 Apr 2005

National clinical trial examines new option for kidney cancer patients

The trial, which opened last September, offers research subjects who qualify a new, targeted therapy in addition to standard immune therapy. The drug combination is being studied in a national Phase II clinical trial led by OHSU Cancer Institute researcher Christopher Ryan, M.D., through the Southwest Oncology Group, one of the largest clinical trial cooperative groups in the United States.

27 Apr 2005

Angiogenesis : Blocking tumor growth and treating infarction - a new target

Our tissues are able to form new blood vessels throughout life. This mechanism, which is called angiogenesis, is essential notably in the case of myocardial infarction, stroke and limb ischemia. The very same mechanism, however, keeps tumors supplied with nutrients and oxygen thus enabling them to continue growing.

27 Apr 2005

Report reveals urgent need to improve physical health of people with Schizophrenia

People with schizophrenia often die prematurely. However researchers from the University of Glasgow and NHS Greater Glasgow assert that much of the excess mortality of schizophrenia is preventable through lifestyle changes and the treatment of common diseases.

27 Apr 2005

Guidelines for research involving human embryonic stem cells

The National Academies today recommended guidelines for research involving human embryonic stem cells, and urged all institutions conducting such research to establish oversight committees to ensure that the new guidelines will be followed.

26 Apr 2005

Search for new multiple sclerosis drug

UT Southwestern Medical Center is the lead research site testing a new treatment for a rare form of multiple sclerosis. Called "primary progressive," this type of MS affects about 15 percent of patients with the neurodegenerative disease.

26 Apr 2005

Physical activity appears to inhibit Alzheimer's

Physical activity appears to inhibit Alzheimer's-like brain changes in mice, slowing the development of a key feature of the disease, according to a new study.

26 Apr 2005

P12 protein influences key cell-signaling pathway

New research shows that a protein produced by a cancer-causing virus influences a key signaling pathway in the immune cells that the virus infects. This stimulates the cells to divide, helping the virus spread through the body.

26 Apr 2005

Herceptin provides hope to new breast cancer sufferers

According to new research, Herceptin, Genentech's breast cancer treatment has shown promise in treating the early stages of breast cancer.

25 Apr 2005

Gene therapy for Alzheimer's disease shows promise

In the first clinical trial of gene therapy for Alzheimer's disease researchers have produced preliminary evidence that gene therapy may slow the decline in mental functioning associated with Alzheimer's disease.

25 Apr 2005

New drug combo helps prevent strokes

A British research team at St. George's Hospital Medical School in London, have found that the addition of the anti-clotting drug Plavix to daily doses of aspirin helps prevent the risk of later strokes better than using aspirin alone.

25 Apr 2005

Simple actions could wipe out heart risks for Asian diabetics

New research, to be revealed on Tuesday 26th of April at the launch of the University of Warwick Medical School's new Clinical Sciences Research Institute at the University Hospital campus at Walsgrave in Coventry, has shown that very simple interventions to target the health care of UK Asian diabetics can almost wipe out the 40% higher risks of heart disease linked to diabetes in that community.

25 Apr 2005

Important new finding about the brain and its stem cells

A family's bravery and generosity in the face of their son's death three years ago has enabled researchers to make an important new finding about the brain and its stem cells.

25 Apr 2005

Risk scores may identify young individuals with atherosclerosis

Young people with atherosclerotic lesions may be identified by a risk score calculated from coronary heart disease factors like obesity, sex, age, cholesterol, and smoking, according to an article in the April 25 issue of Archives of Internal Medicine.

25 Apr 2005

Pattern of gene expression predicts multiple drug resistance, treatment failure in pediatric leukemia

The discovery of a specific pattern of gene expression linked to multiple-drug resistance of leukemic cells is giving researchers crucial information into why standard therapies fail to cure some children with acute lymphoblastic leukemia (ALL). This finding, from investigators at St. Jude Children’s Research Hospital, could lead to development of drugs that would overcome that resistance.

24 Apr 2005

Increasing benefit seen in novel drug AMN107, that treats Gleevec resistance

An investigational drug is producing powerful responses in patients resistant to Gleevec, the targeted therapy that helps most people diagnosed with chronic myeloid leukemia (CML), an international research team headed by investigators at The University of Texas M. D. Anderson Cancer Center is reporting.

23 Apr 2005

Smad7 protein levels may predict prostate cancer therapy response

Levels of the Smad7 protein may predict therapeutic response in patients with prostate cancer according to research published by investigators at the Uppsala Branch of the Ludwig Institute for Cancer Research (LICR).

23 Apr 2005

Testing new manic depression drugs in slime mould

Research by University College London (UCL) scientists could lead to the development of more effective drugs for treating manic depression thanks to a new screening approach developed in a "slime mould" - a microbe that lives in leaves and dung on forest floors.

23 Apr 2005

Drinking wine or beer has same result: higher blood pressure

Whether the drink of choice is a frosty beer or a full-bodied red wine, the effect is the same – higher blood pressure, according to research reported in Hypertension: Journal of the American Heart Association.

23 Apr 2005