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Research could lead to new drugs that combat HIV infection by shutting down the virus's assembly lines

After infecting a susceptible cell, the human immunodeficiency virus hijacks that cell's normal machinery to produce carbon copies of itself. New HIV particles roll off the cellular assembly lines, burst like bubbles out of the cell, and float off to invade other cellular factories.

14 Mar 2005

Alcohol intervention attempted for violent males

Serious facial and dental injuries often go hand-in-hand with heavy alcohol consumption and violent behavior, especially by teenage boys and young men.

13 Mar 2005

Gene for AMD has now been identified by researchers

Age-related macular degeneration (AMD) is a debilitating eye disease affecting about 15 million people in the United States.

13 Mar 2005

Active brains stave off Alzheimer's signs

Mice who keep busy playing with toys also keep their brains and bodies active; more importantly, they also have lower levels of the peptides and brain plaques associated with Alzheimer's disease, compared to mice raised in environments not "enriched" with chew toys, running wheels,and tunnels, according to a new study in the 11 March issue of the journal Cell.

13 Mar 2005

Secondhand smoke causes breast cancer

A California agency, the Air Resources Board, which first linked secondhand smoke to heart disease, now says secondhand smoke causes breast cancer too.

10 Mar 2005

Emergency clopidogrel could save thousands of lives worldwide

Adding the anti-platelet drug clopidogrel to aspirin for the emergency treatment of heart attacks could save thousands of lives a year worldwide and prevent thousands of repeat heart attacks and strokes, according to new research presented at the American College of Cardiology annual conference.

9 Mar 2005

Mouse gene shows new mechanism behind cardiac infarction in man

A gene that, in different variants, increases or decreases the level of atherosclerosis has been identified in mice. The corresponding human gene has been shown to play a role in the development of myocardial infarction.

9 Mar 2005

Telomerase finding has major implications for cancer

UCLA biochemists have determined the three-dimensional structure of a major domain of telomerase, the enzyme that helps maintain telomeres - small pieces of DNA on the ends of chromosomes that act as protective caps - allowing DNA ends to be copied completely when cells are replicated.

9 Mar 2005

Overlapping signals in embryo help get the backbone right

A major step in the development of the vertebrate embryo - the establishment of a back that morphs into a brain, spinal cord and muscles - turns out to be so important that the body uses at least three signals to make sure it happens properly.

9 Mar 2005

Finding may open new horizons for understanding the initiation of chemically induced cancers

A team from the chemistry and biology departments of New York University, in collaboration with Memorial Sloan Kettering Cancer Center (MSKCC), has uncovered a conformational switch - a change in shape in a carcinogen-damaged DNA site - in tumor suppressor genes altered by a known cancer-causing chemical found in cigarette smoke.

9 Mar 2005

Efforts to improve the quality of post-heart attack care working better for men than for women

Efforts to improve the quality of post-heart attack care in hospitals are working - but they appear to be working better for men than for women, new research shows.

9 Mar 2005

First reliable measure of neurobehavioral functioning during coma from severe brain injury

A Northwestern University researcher has developed the first truly reliable measure of neurobehavioral functioning during coma from severe brain injury that predicts recovery of consciousness up to one year after injury, with up to 86 percent certainty.

9 Mar 2005

Commonly used anesthetic regimen appears to have no negative effects on the developing brain of the fetus

An anesthetic regimen commonly used during surgery on pregnant mothers appears to have no negative effects on the developing brain of the fetus, according to a new study on sheep conducted by Duke University Medical Center researchers.

9 Mar 2005

Dental medicine is on the brink of profound change

Advances in stem cell biology will improve our understanding of degenerative diseases and assist in developing therapies for replacing damaged or diseased parts/tissues.

9 Mar 2005

Evidence for a self-reinforcing "memory loop" - brain emotional center triggers the memory center

Researchers exploring the brain structures involved in recalling an emotional memory a year later have found evidence for a self-reinforcing "memory loop" - in which the brain's emotional center triggers the memory center, which in turn further enhances activity in the emotional center.

8 Mar 2005

Nature of electrical abnormalities occurring during the development of heart failure

A Johns Hopkins undergraduate student has contributed to new research showing that electrical changes in the heart leading to heart failure can occur long before a patient exhibits any clinical symptoms.

8 Mar 2005

Progress toward development of a breast cancer vaccine

Progress toward development of a breast cancer vaccine has been reported by researchers at Washington University School of Medicine and the Siteman Cancer Center in St. Louis.

8 Mar 2005

Asthma relapse linked to allergies

Researchers have found that some children who supposedly outgrew their asthma saw it re-appear by the time they reached their mid-20s.

8 Mar 2005

Cigarette smoke worsens respiratory infections in infants

Studying Respiratory Syncytial Virus (RSV) to learn what puts children at risk for the most severe infections, Washington University researchers at St. Louis Children's Hospital found that a child's age at the time of infection and whether that child lives with a smoker could mean the difference between the sniffles and the intensive care unit.

8 Mar 2005

Pet scanning could cut use of angiograms and bypass surgery, as well as patient costs

Using positron emission tomography (PET) scanning rather than other types of imaging as the first tool to diagnose heart-vessel blockages is more accurate, less invasive and saves dollars, a study by a University at Buffalo team has shown.

8 Mar 2005

Medical Research News

Research could lead to new drugs that combat HIV infection by shutting down the virus's assembly lines

Alcohol intervention attempted for violent males

Gene for AMD has now been identified by researchers

Active brains stave off Alzheimer's signs

Secondhand smoke causes breast cancer

Emergency clopidogrel could save thousands of lives worldwide

Mouse gene shows new mechanism behind cardiac infarction in man

Telomerase finding has major implications for cancer

Overlapping signals in embryo help get the backbone right

Finding may open new horizons for understanding the initiation of chemically induced cancers

Efforts to improve the quality of post-heart attack care working better for men than for women

First reliable measure of neurobehavioral functioning during coma from severe brain injury

Commonly used anesthetic regimen appears to have no negative effects on the developing brain of the fetus

Dental medicine is on the brink of profound change

Evidence for a self-reinforcing "memory loop" - brain emotional center triggers the memory center

Nature of electrical abnormalities occurring during the development of heart failure

Progress toward development of a breast cancer vaccine

Asthma relapse linked to allergies

Cigarette smoke worsens respiratory infections in infants

Pet scanning could cut use of angiograms and bypass surgery, as well as patient costs

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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