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Novel mechanism of PDHX acetylation linked to hepatocellular carcinoma progression

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

3 Mar 2025

Talk therapy delivered by non-specialists effective for pregnant and postpartum individuals

Approximately one in five of pregnant and postpartum individuals experience depression and anxiety, yet less than 10 per cent receive proper treatment.

3 Mar 2025

Research reveals key parental risk factors for child abuse

Child maltreatment has been the focus of two separate studies led by UQ researchers, who examined the main parental risk factors that lead to child abuse, as well as the behavioural impacts later in life.

3 Mar 2025

Hallucinogen use linked to increased risk of mortality in emergency care patients

People seeking emergency care for hallucinogen use were at 2.6-fold higher risk of death within 5 years than the general population, according to a new study published in CMAJ.

3 Mar 2025

Co-occurring mutations may limit effectiveness of KRAS G12C inhibitors in colorectal and pancreatic cancer

Colorectal cancer and pancreatic ductal adenocarcinoma that harbored the KRAS G12C mutation often carried other genetic alterations that can be associated with resistance to KRAS G12C inhibitors, despite no prior treatment with this therapy, according to recent results from a large multidatabase analysis.

3 Mar 2025

Sleep patterns could indicate hidden consciousness in brain injury patients

Several studies in the past decade have revealed that up to a quarter of unresponsive patients with recent brain injuries may possess a degree of consciousness that's normally hidden from their families and physicians.

3 Mar 2025

Study identifies key role of JMJD1C in acute myeloid leukemia

Acute myeloid leukemia (AML) is one of the most aggressive and genetically complex cancers, marked by the unchecked growth of immature myeloid cells.

3 Mar 2025

Stress granules as potential biomarkers for neurodegenerative diseases

Stress granules (SGs) are transient organelles that form when cells experience stress, serving as critical hubs for RNA metabolism and cellular survival.

3 Mar 2025

Study identifies key genetic markers for SCA6 diagnosis

The Department of Neurology at Niigata University and National Center of Neurology and Psychiatry NCNP has identified pathogenic thresholds for the CAG repeat units (RU) of the CACNA1A gene that causes SCA6.

3 Mar 2025

New blood biomarkers could revolutionize gallbladder cancer diagnosis

Researchers at Karolinska Institutet and Karolinska University Hospital have identified biomarkers in the blood that can be used to distinguish gallbladder cancer from inflammation of the gallbladder.

3 Mar 2025

Skin organoids show promise for treating frostbite injuries

Frostbite is a severe cold injury that affects millions worldwide, often resulting in prolonged recovery, scarring, and long-term complications such as chronic pain and dysfunction.

3 Mar 2025

Targeting SSAT enzyme offers new hope for psoriasis treatment

Psoriasis is one of the most common chronic inflammatory skin diseases, affecting around 250,000 people in Austria.

3 Mar 2025

British Heart Foundation’s Centre of Research Excellence launches at The University of Manchester

The University of Manchester has launched the British Heart Foundation (BHF) Manchester Centre of Research Excellence following an award of £4 million to support world-class cardiovascular disease from the leading charity.

From The University of Manchester 3 Mar 2025

Mediterranean diet reduces risk of obesity-related cancers

Greater adherence to the Mediterranean diet is associated with a modest reduction in obesity-related cancer risk

2 Mar 2025

Intermittent fasting cuts heart attack risk by preventing dangerous blood clots

Intermittent fasting may reduce the risk of blood clots and cardiovascular disease by inhibiting platelet activation.

2 Mar 2025

Scientists uncover how herpes virus fuels Alzheimer’s disease

Herpesvirus infection may contribute to Alzheimer’s disease through transposable element activation and neuroinflammation.

2 Mar 2025

New study confirms GLP-1 medications are safe for mental health in diabetes

Researchers assess whether GLP-1 receptor agonists increase the risk of suicide, self-harm, or suicidal ideation in type 2 diabetes patients.

2 Mar 2025

Tomatoes and lycopene: Can eating more reduce your cancer risk?

Higher dietary and blood lycopene levels are linked to a reduced risk of cancer, with the strongest protective effects seen against lung cancer mortality. However, these findings are observational and require further research.

2 Mar 2025

Early CPAP treatment may reduce Parkinson's disease risk in people with sleep apnea

People with obstructive sleep apnea have an increased risk of Parkinson's disease, but if started early enough, continuous positive airway pressure (CPAP) may reduce that risk, according to a preliminary study released today, March 2, 2025, that will be presented at the American Academy of Neurology's 77th Annual Meeting taking place April 5–9, 2025, in San Diego and online.

2 Mar 2025

TFE3 activation shows promise for counteracting Parkinson's disease pathology

This recent study highlights the neuroprotective potential of TFE3, a transcription factor that plays a pivotal role in counteracting key pathological mechanisms associated with Parkinson's disease (PD).

2 Mar 2025