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Enzyme known as cathepsin G may be a target for anti-inflammatory treatments

The finding by researchers at Washington University School of Medicine in St. Louis shows that an enzyme known as cathepsin G regulates the ability of immune cells known as neutrophils to secrete chemicals that attract other immune cells and start the local inflammatory process. Over time, the excessive accumulation of immune cells can lead to tissue and cartilage damage in joints, causing pain and limiting mobility.

27 Jun 2005

Tricirbine may help fight cancers

H. Lee Moffitt Cancer Center & Research Institute, working in partnership with the University of South Florida (USF), has discovered a new use for an old, previously discredited anti-cancer drug that could add another weapon in the arsenal against several cancers, including tumors of the breast, ovary, colon, skin and prostate.

27 Jun 2005

Technique called phylogenetic footprinting reveals new gene regulation system

By comparing 140 sequenced bacterial genomes, researchers have uncovered a system for regulating genes essential to bacterial replication - and they did it solely by computer keystrokes and mouse clicks.

27 Jun 2005

How can the U.S. health-care system prepare for the huge wave of dementia patients expected by 2010?

How can the U.S. health-care system and more specifically, primary care doctors - the physicians from whom older adults receive most of their care - prepare for the huge wave of dementia patients expected to engulf us in 2010, the year the baby boomers begin to reach 65?

27 Jun 2005

OHSU scientists say low FOXP3 means fewer disease-fighting cells, but new drug may help multiple sclerosis

Oregon Health & Science University researchers have measured genetic changes reflecting a drop in the body's ability to suppress inflammatory cells that attack nerve fibers and promote progression of multiple sclerosis.

27 Jun 2005

Increasing stiffness of the aging eye may make older adults more susceptible to eye damage following trauma

Using a computer model of the eye, Stitzel and colleagues investigated possible injury mechanisms in the eyes of elderly individuals and the effects of lens stiffness on injury prediction by the model. The new data document that the risk of certain types of eye injury increases with age.

27 Jun 2005

Researchers discover new molecular mechanism that may allow for stem cell-based therapies to treat eye disorders such as retinal degeneration

The finding also reveals how the retina's own stem cells can be directed to aid the growth of new cells to replace diseased or dying ones in the eye. Study results appear in the June 24 issue of the journal Science.

27 Jun 2005

New research raises the possibility that the risk of developing arsenic-related disease is not the same for everybody

Children with a particular variation in the CYT19 gene metabolize arsenic differently than adults with the same genetic variant, according to a new research report. The findings have important implications for the safety of drinking water worldwide and the use of arsenic as a cancer drug.

27 Jun 2005

Unknown factors make Scots people more prone to heart disease

The findings, which are published in the current edition of the Journal of Epidemiology and Community Health, conclude that although successful campaigns to get Scots to live a healthier lifestyle will reduce rates of heart disease in Scotland, they will not do much to narrow the gap in heart disease rates between Scotland and England.

26 Jun 2005

Expression profiles and functional analyses of Wnt-related genes in human joint disorders

The cellular signaling protein Wnt, which is involved in embryonic development and cancer, contributes to disease progression of both rheumatoid arthritis and osteoarthritis.

26 Jun 2005

Adult nasal spray helps teenagers cope with migraines

A Florida researcher reports that a prescription nasal spray approved for adults with migraines also helps teenagers and potentially offers relief for a population which is underserved in this respect.

26 Jun 2005

Naturally produced 'cannabis' in the brain helps with pain relief

Researchers in the United States have found that a cannabis like chemical produced naturally in the brain helps with pain relief.

23 Jun 2005

Double whammy of chemo plus surgery extends life for lung cancer patients

Recent research which has shown that chemotherapy can significantly lengthen life in many patients with lung cancer, has meant that doctors, for the first time in decades, have begun making major changes in the treatment of the disease.

23 Jun 2005

New drug delays the onset of diabetes

New research has shown that an experimental drug, designed to reset the body's immune system, could delay the need for extra insulin in some people with recently diagnosed juvenile diabetes.

23 Jun 2005

Researchers develop method that can help doctors choose the best combination of drugs for fighting cancer

The method is based on a mathematical model that determines when a cancer becomes drug-resistant during therapy. It does this by estimating the probability of finding drug-resistant mutant cells at different stages of cancer progression and examining the fate of individual mutant colonies during therapy.

21 Jun 2005

Chemicals found in everyday products and food have subtle but potentially damaging effects on sperm fertility

Professor Lynn Fraser told the 21st annual conference of the European Society of Human Reproduction and Embryology today (Wednesday), that her previous research had shown that certain chemicals known to mimic the female sex hormone, oestrogen, could individually affect the correct functioning of mouse sperm, but now her new research showed that when the chemicals were combined they had an even stronger effect.

21 Jun 2005

Research shows self-selected treatment, punishment reduces destructive behavior

Punishment is often a necessary ingredient in any method aimed at making aggressive special-needs children less destructive, according to new research in the Journal of Applied Behavior Analysis.

21 Jun 2005

Researchers discover mechanism that causes a protein to clump together in brain cells of people with Parkinson's disease

The protein clumping is part of a "vicious cycle," the researchers said. As the proteins cluster, they inhibit an enzyme that normally breaks them down, leading to the formation of even more masses.

21 Jun 2005

Researchers isolate substance most responsible for the tissue damage that follows initial spinal cord injury

Purdue University researchers may have isolated the substance most responsible for the tissue damage that follows initial spinal cord injury, a discovery that could also improve treatments for a host of other neurodegenerative conditions.

21 Jun 2005

Breakthrough in understanding of children's brain development to help parents set kids on path to emotional, intellectual health

A major new research initiative at York University will build on new knowledge of the brain’s development, and help set children --including those with developmental disorders -- on the path towards emotional and intellectual health.

21 Jun 2005

Medical Research News

Enzyme known as cathepsin G may be a target for anti-inflammatory treatments

Tricirbine may help fight cancers

Technique called phylogenetic footprinting reveals new gene regulation system

How can the U.S. health-care system prepare for the huge wave of dementia patients expected by 2010?

OHSU scientists say low FOXP3 means fewer disease-fighting cells, but new drug may help multiple sclerosis

Increasing stiffness of the aging eye may make older adults more susceptible to eye damage following trauma

Researchers discover new molecular mechanism that may allow for stem cell-based therapies to treat eye disorders such as retinal degeneration

New research raises the possibility that the risk of developing arsenic-related disease is not the same for everybody

Unknown factors make Scots people more prone to heart disease

Expression profiles and functional analyses of Wnt-related genes in human joint disorders

Adult nasal spray helps teenagers cope with migraines

Naturally produced 'cannabis' in the brain helps with pain relief

Double whammy of chemo plus surgery extends life for lung cancer patients

New drug delays the onset of diabetes

Researchers develop method that can help doctors choose the best combination of drugs for fighting cancer

Chemicals found in everyday products and food have subtle but potentially damaging effects on sperm fertility

Research shows self-selected treatment, punishment reduces destructive behavior

Researchers discover mechanism that causes a protein to clump together in brain cells of people with Parkinson's disease

Researchers isolate substance most responsible for the tissue damage that follows initial spinal cord injury

Breakthrough in understanding of children's brain development to help parents set kids on path to emotional, intellectual health

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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