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Finding could provide targets for diagnosis, prognosis, therapy of prostate cancer

Researchers led by Dr. Shiv Srivastava from the Center for Prostate Disease Research (CPDR), Uniformed Services University of the Health Sciences (USU), report the groundbreaking discovery of the ETS-Related Gene (ERG) as one of the frequent proto-oncogene overexpressions in prostate cancer cells.

10 Jun 2005

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

Using targeted RNA interference, or RNAi libraries, researchers at Harvard Medical School describe the first large-scale classification of kinase and phosphatase gene families on the basis of their role in apoptosis and cell survival. This study appears in the June issue of Nature Cell Biology.

10 Jun 2005

Brain shrinkage appears to have no impact on an individual's capacity to think or learn

The research is part of a 20-year study by the ANU Centre for Mental Health Research called PATH Through Life and suggests a revision of long-standing views on the impact of age-related brain shrinkage.

10 Jun 2005

No significant long-term benefit in administering immediate treatment to those with early epilepsy

Around 500,000 people in the UK suffer from epilepsy, making it the most common serious neurological condition. Many of those who develop epilepsy start having seizures during childhood, but it can develop at any age.

10 Jun 2005

DNA discovery may help explain disorders such as autism

Researchers have made a discovery that may in future help to explain many aspects of human social behavior and disorders such as autism.

10 Jun 2005

Exercise helps recovery after chemotherapy for breast cancer

Exercise after chemotherapy for breast cancer boosted the activity of infection-fighting T cells in women who worked out regularly, according to data from a study conducted at Penn State University under the direction of Andrea Mastro, professor of microbiology and cell biology.

10 Jun 2005

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Researchers at Johns Hopkins have uncovered how a majority of the genetic changes in the hepatic-C virus, the most common cause of liver disease, allow it to evade the body's immune system during infection.

10 Jun 2005

Researchers explain how ubiquitin function is determined

University of Maryland researchers have explained, for the first time, why the linkage between the cell-regulating protein molecules called ubiquitins determines their function.

10 Jun 2005

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer’s disease have an immune defect making it difficult to clean away these wastes.

From MP Biomedicals, LLC 10 Jun 2005

Variations in genetic code affect social behavior

Why are some people shy while others are outgoing? A study in the current issue of Science demonstrates for the first time that social behavior may be shaped by differences in the length of seemingly non-functional DNA, sometimes referred to as junk DNA.

9 Jun 2005

US specialists call for heart patients to be screened for psychological distress

Heart patients should be screened for psychological distress and, if necessary, referred for help from mental health professionals, according to the authors of research published today (Thursday 9 June) in the European Heart Journal.

9 Jun 2005

Exposing SMA-affected cells to aminoglycoside drugs can increase SMN

MDA grantee Christian Lorson at the University of Missouri was on a team that found that exposing cells carrying a mutation that causes spinal muscular atrophy (SMA) to drugs in the aminoglycoside family helps them produce more of the needed SMN protein, a lack of which leads to SMA.

9 Jun 2005

Experimental drug therapy could open new window for treatment of deadly stroke

A new type of drug therapy that is currently being tested in Canada could significantly reduce the death rate caused by the deadliest form of stroke. According to the Canadian Heart and Stroke Foundation, new developments in stroke research make it more important than ever that Canadians recognize and react to the warning signs of stroke.

9 Jun 2005

Research opens up new directions for studying prion diseases in humans

The mysterious, highly infectious prions, which cause the severe destruction of the brain that characterizes "mad cow disease" and several human brain degenerative disorders, can be rendered harmless in the laboratory by a slight alternation of the three-dimensional conformation or shape of the prion protein's structure.

9 Jun 2005

Researchers determine potentially safer way to diagnose food allergy

Researchers may have defined a safer and less expensive way to determine the presence of food allergy in children, according to new research in the Journal of Allergy & Clinical Immunology (JACI). The JACI is the peer-reviewed scientific journal of the American Academy of Allergy, Asthma & Immunology (AAAAI).

9 Jun 2005

Physical activity in old age is beneficial for physical, cognitive and psychological health

Older persons who are capable of physical activity but do not exercise have an increased risk of future problems walking or climbing stairs, according to research published in the Journal of the American Geriatrics Society.

9 Jun 2005

Promising new vaccine candidate to prevent middle ear infections

Hoping to prevent ear infections for the more than 15 million children in the United States who suffer from them, a promising new vaccine candidate to prevent middle ear infections (otitis media) is being developed by researchers at the Columbus Children’s Research Institute (CCRI) on the campus of Columbus Children’s Hospital.

9 Jun 2005

Fundamental insights in how amyloid fibers form

Amyloid fibers are best known as the plaque that gunks up neurons in people with neurodegenerative illnesses such as Alzheimer's and Creutzfeldt-Jacob disease--the human analog of mad cow disease.

9 Jun 2005

MicroRNAs play an important role in human cancer

Over the past few years, scientists have discovered that a new class of genetic regulators called "microRNAs" influences normal human growth and development. Now, researchers have found that microRNAs also play an important role in human cancer. The findings are published in today's issue of the journal Nature (June 9).

9 Jun 2005

Density of breast tissue can directly influence tumour development

New research suggests that there is a direct relationship between the density of breast tissue, and the risk of developing tumours in dense areas of the breast.

8 Jun 2005

Medical Research News

Finding could provide targets for diagnosis, prognosis, therapy of prostate cancer

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

Brain shrinkage appears to have no impact on an individual's capacity to think or learn

No significant long-term benefit in administering immediate treatment to those with early epilepsy

DNA discovery may help explain disorders such as autism

Exercise helps recovery after chemotherapy for breast cancer

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Researchers explain how ubiquitin function is determined

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

Variations in genetic code affect social behavior

US specialists call for heart patients to be screened for psychological distress

Exposing SMA-affected cells to aminoglycoside drugs can increase SMN

Experimental drug therapy could open new window for treatment of deadly stroke

Research opens up new directions for studying prion diseases in humans

Researchers determine potentially safer way to diagnose food allergy

Physical activity in old age is beneficial for physical, cognitive and psychological health

Promising new vaccine candidate to prevent middle ear infections

Fundamental insights in how amyloid fibers form

MicroRNAs play an important role in human cancer

Density of breast tissue can directly influence tumour development

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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