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Blocking the COX-1 enzyme might be the answer in ovarian cancer treatment

Researchers at Vanderbilt University Medical Center in a new report say that blocking the COX-1 enzyme - not COX-2 - might lead to a way to prevent and treat the most common and fatal form of ovarian cancer.

2 May 2005

Little known enzyme ACAT2 appears to be a factor in cardiovascular disease

New research suggests that a little-studied enzyme ACAT2, may play a major role in cardiovascular disease because it alters the molecular structure of cholesterol.

2 May 2005

Specific behaviors seen in infants can predict autism, new research shows

Canadian researchers have become the first to pinpoint specific behavioral signs in infants as young as 12 months that can predict, with remarkable accuracy, whether a child will develop autism.

1 May 2005

Use of agricultural insecticides linked to lasting neurological problems for farmers

New research shows that farmers who used agricultural insecticides experienced increased neurological symptoms, even when they were no longer using the products. Data from18,782 North Carolina and Iowa farmers linked use of insecticides, including organophosphates and organochlorines, to reports of reoccurring headaches, fatigue, insomnia, dizziness, nausea, hand tremors, numbness and other neurological symptoms. Some of the insecticides addressed by the study are still on the market, but some, including DDT, have been banned or restricted.

1 May 2005

Asthma and diabetes sufferers could benefit nano-particle research

Patients suffering from conditions as diverse as asthma and diabetes could benefit from research at Cardiff University to improve the effectiveness of drugs taken through spray inhalers.

1 May 2005

Prenatal exposure to cocaine effects problem-solving later in life

Children exposed to cocaine before birth show subtle but discernible differences in their ability to plan and problem-solve once they reach school age, University of Florida researchers report.

1 May 2005

Age-related macular degeneration is triggered, possibly by an infection

Age-related macular degeneration, the leading cause of blindness in the elderly, occurs when a common inherited gene variation is triggered, possibly by an infection, according to a new study led by researchers at Columbia University Medical Center and the University of Iowa, with an international research team.

1 May 2005

Computerized tools for diagnosing heart attack could be inaccurate in some people

A computerized tool to help emergency room physicians determine whether a patient is having a heart attack may not work as well among some racial and ethnic groups, according to research of almost 12,000 patients at nine medical centers.

1 May 2005

Vitamin C may have potential to counteract negative impacts of smoking in unborn babies

Research conducted in monkeys at the Oregon National Primate Research Center, Oregon Health & Science University, suggests high doses of vitamin C may have potential to counteract some negative impacts of smoking in unborn babies.

1 May 2005

Blocking the COX-1 enzyme might prevent and treat the most common and fatal form of ovarian cancer

Blocking the COX-1 enzyme - not COX-2 - might lead to a way to prevent and treat the most common and fatal form of ovarian cancer, researchers at Vanderbilt University Medical Center reported this week.

1 May 2005

Researchers determine mechanism of action of chemotherapy drug motexafin gadolinium

The chemotherapy drug motexafin gadolinium (brand name: Xcytrin, manufactured by Pharmacyclics, Inc.) works to thwart cancer cells by disrupting key enzymes involved in cellular metabolism, according to a team of researchers led by Joseph Hacia, Ph.D., assistant professor of biochemistry and molecular biology at the Keck School of Medicine of the University of Southern California.

1 May 2005

Antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system

By studying animals, Johns Hopkins researchers have discovered that the antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system, problems that can develop even though antiretroviral therapy controls the virus elsewhere in the body.

1 May 2005

Obese people - add yet another worry to the list

Dementia is now the latest scare factor to be added to an ever growing list of threats which so far includes diabetes, heart disease and stroke, which obese people are apparently more prone to.

1 May 2005

Pollutants appear to have an affect on sex chromosome

A team of researchers from Lund University in Sweden have found that exposure to a class of environmental pollutants can change the ratio of sperm carrying male and female chromosomes.

1 May 2005

Researchers show protein's role in stopping bacterial-induced inflammation

In findings that could have implications for autoimmune disorders and drug-resistant bacterial infections, researchers at the University of California, San Diego (UCSD) School of Medicine have identified a key protein involved in the appropriate shut-down of inflammation following an immune response to invading pathogens.

28 Apr 2005

Research may re-define management of heart failure in diabetes

Control of oxidised copper levels in the body may be as important as lowering blood glucose levels in preventing cardiovascular complications in diabetes mellitus, according to New Zealand researchers.

28 Apr 2005

Cancer treatment - timing is everything

Research led by a cancer biologist at The Cleveland Clinic Lerner Research Institute has identified a molecular mechanism that links the body's internal clock to daily variations in how a patient responds to cancer treatment.

28 Apr 2005

New centre launched to investigate link between human sugars and disease

A multidisciplinary centre launched today will promote a far broader understanding of the role sugars play in human disease, scientists say.

28 Apr 2005

Highly refined soybean oil does not cause reactions in people who are allergic to soybeans

Recent University of Nebraska-Lincoln research on soybean oil is helping shape food allergen labeling laws here and abroad.

28 Apr 2005

$Taking extra vitamin D and calcium will not prevent fractures in seniors$

Taking extra vitamin D and calcium will not prevent fractures in seniors

Surprising new research has found that taking vitamin D or calcium does not help prevent repeat fractures in elderly people. In two studies by teams at Aberdeen and York universities, researchers looked at people who had already had a fracture due to osteoporosis, a condition which increases a person's risk of bone fractures.

28 Apr 2005