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Stress response proteins offer a promising target for a novel drug guidance system

Their study, published in the September issue of the journal Cancer Cell, demonstrates how researchers can find protein tags that are unique to cancer cells and then tweak a drug delivery system to zero in on those tags and destroy the cells.

21 Sep 2004

HER-2 cell surface receptors tun on genes associated with carcinogenesis

Researchers at The University of Texas M. D. Anderson Cancer Center now have evidence that receptors found on tumors that were believed to function only on the surface of cells can actually switch on genes inside a cell's nucleus, thus promoting cancer development in two distinct ways.

21 Sep 2004

Laser therapy and tacrolimus ointment best for vitiligo

Patients with vitiligo, a skin disorder characterized by patches of white, or de-pigmented skin, had better repigmentation of these patches when they were treated with a combination of laser therapy and tacrolimus ointment than patients treated with laser therapy alone

21 Sep 2004

Obesity makes surgery more difficult and risky

Critically injured obese trauma patients have higher rates of death than nonobese trauma patients, according to an article in the September issue of The Archives of Surgery, one of the JAMA/Archives journals.

21 Sep 2004

Streptococcus bacteria uses sword and shield to fight white blood cells

A single gene called cylE within the important bacterial pathogen Group B Streptococcus (GBS), controls two factors that act together as a “sword” and “shield” to protect the bacteria from the killing effects of the immune system’s white blood cells

21 Sep 2004

A low salt diet can be extremely dangerous for elderly people

Professor Füsgen presented his findings at the European Geriatrics Congress in Vienna, which ended yesterday (September 19). They show that the symptoms of hyponatraemia (low sodium level in the blood), which are tiredness, difficulty in concentrating and loss of balance, can develop into confusion and even coma if left untreated.

20 Sep 2004

New imaging analysis techniques to probe causes of dyslexia

Using sophisticated new software that integrates a variety of imaging methods, Wake Forest University Baptist Medical Center researchers will probe the mystery of what causes dyslexia with a four-year, $2.3 million grant from the National Institutes of Health.

20 Sep 2004

Certain cancers might one day be cured without the use of toxic chemotherapy and radiation

The eradication of brain tumors in mice following treatment with a novel drug suggests that certain cancers might one day be cured without the use of toxic chemotherapy and radiation.

20 Sep 2004

New anti-inflammatory strategy for cancer therapy

A new strategy for cancer therapy, which converts the tumor-promoting effect of the immune system’s inflammatory response into a cancer-killing outcome, is suggested in research findings by investigators at the University of California, San Diego (UCSD) School of Medicine.

20 Sep 2004

Research may provide a better understanding of the mental retardation observed in Cri-du-Chat Syndrome

By specifically deleting the adhesion protein d-catenin, which is found exclusively in the brain, researchers at UCLA have found evidence that loss of d-catenin produces severe cognitive and synaptic dysfunction.

20 Sep 2004

Vanilla may become a drug to treat sickle cell disease

In addition to its popular role in flavoring ice cream, fudge and cake frosting, vanilla may have a future use as a medicine. Recent laboratory research has strengthened the possibility that a form of vanilla may become a drug to treat sickle cell disease.

20 Sep 2004

Non-human primates should never be considered as source animals for any future clinical trials of animal-to-human transplantation

Australia’s leading health advisory body, the National Health and Medical Research Council, says there should be a five-year moratorium on any clinical research into animal-to-human whole organ transplants in Australia.

20 Sep 2004

Breakthrough in spinal regeneration research

University of Queensland researchers are claiming a breakthrough in spinal regeneration research with the discovery of a molecule that blocks regrowth of damaged nerve processes.

20 Sep 2004

Today’s scientists have the skills and experience to transplant a human face

A University of Louisville-led research team studying the face transplant has developed guidelines it says are critical to the success of the still-untried procedure.

20 Sep 2004

Resveratrol in red wine, is thought to contribute to improved cardiovascular effects associated with moderate consumption of red wine

Researchers funded by the National Science Foundation (NSF) and affiliated with the Salk Institute in San Diego, Calif., have succeeded in converting chalcone synthase, a biosynthetic protein enzyme found in all higher plants, into an efficient resveratrol synthase.

20 Sep 2004

Genome researchers to look at 1918 Spanish flu

University of Washington researchers will be taking part in a multi-site project examining a portion of the genome of the strain of influenza responsible for the "Spanish Flu" outbreak in 1918.

20 Sep 2004

New oral gel used instead of injection to deliver drugs

Scientists in India have developed a new gel that is taken orally and is capable of delivering drugs to manage diseases often requiring an injection.

20 Sep 2004

Project to find out how European governments could fight obesity

In response to the alarming rise in obesity across the developed world, a University of Sussex food policy researcher is leading a project to find out how European governments could fight the flab.

20 Sep 2004

Humans are in fact quite rational; they just do not trust what people in lab coats tell them

New research indicates that humans are in fact quite rational; they just do not trust what people in lab coats tell them. The research suggests that by taking doubt into account, psychologists have the opportunity to strengthen the predictive power of many commonly used models and potentially better understand human behavior.

18 Sep 2004

Research findings may help stave off full-blown diabetes

A new study by researchers at Joslin Diabetes Center sheds light on the key mechanisms by which new pancreatic beta cells normally form in response to insulin resistance. These findings may some day help researchers devise ways of staving off full-blown diabetes.

18 Sep 2004