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Simple blood tests which could predict the severity of osteoarthritis

Bristol researchers are hoping to develop simple blood tests which could predict the severity of osteoarthritis, a common, disabling joint condition which affects more than two million people in the UK.

29 Mar 2004

Program to help health-carers reduce hospital falls by up to 30%

Researchers at the University of Melbourne have developed a program that could help health-carers reduce by up to 30% the number of falls incurred by patients while in hospital.

29 Mar 2004

Halting the development of certain pancreatic, ovarian, colon and lung cancers may be possible with new therapy

By investigating a single molecule that influences cell growth, a research group in the Purdue Cancer Center, including Brian S. Henriksen, has gained new insight into the chain of events that make some cancer cells divide uncontrollably, insight that may eventually lead to a way to break that chain, stopping cancer in its tracks. The molecule, known as Icmt, has a critical role in the development of Ras, an ordinarily beneficial protein that tells a cell to divide. The research group has determined how to inhibit Icmt's influence on Ras, without which the protein cannot develop effectively into an instigator of cell growth.

28 Mar 2004

A simple dietary supplement may also help to prevent strokes

A simple dietary supplement may not only give relief to some of the more than 400,000 New Zealanders that suffer from the pain of migraine headaches, but may also help to prevent strokes.

28 Mar 2004

Haemophilia Society President presents Hepatitis C (HCV) Facts to UK Government

Haemophilia Society President to challenge government for second time in Lords question on proposed Hepatitis C ex gratia payment scheme On Thursday 25 March, the first business in the House of Lords will be further questioning of Ministers by the Haemophilia Society’s President, Lord Morris of Manchester.

27 Mar 2004

£35m needed to boost M.E./Chronic Fatigue Syndrome research

National charity Action for M.E. is asking the government for £35 million to find a cure for M.E. - also known as Chronic Fatigue Syndrome. With government plans to boost medical research funding to £1.2bn per year M.E. research must be considered a priority area of investment.

27 Mar 2004

Researchers have successfully grafted human breast tissue into the mammary glands of mice

The last few years have witnessed critical advances in breast cancer therapies. Still, the disease afflicts one in eight American women, and scientists have yet to develop a living model with which they can study the intricacies of human breast-tumor behavior.

26 Mar 2004

p53 protein peptide stops cancer in its tracks

Researchers have dreamed of thwarting cancer by using proteins that halt cell growth and kill the tumor. In theory, the approach should work. In practice, however, scientists have not had an easy time of getting tumor suppressor proteins into cells where they can block growth effectively.

26 Mar 2004

A common antibiotic used to treat arthritis and acne shows promise for limiting the severity of spinal cord and brain injuries

When a fall, car crash, bullet, or knife crushes or cuts a spinal cord, the injury does not stop there. Rather, tissues continue to discharge toxic chemicals for hours, even days and weeks. These chemicals kill and disable nerve cells some distance away from the core injury, compounding the damage and making rehabilitation more difficult or impossible.

26 Mar 2004

Oral medication for diabetes a step closer

University of Toronto researchers have shown that "designer molecules" can interact with the body's insulin receptor, a step toward the development of an oral medication for diabetes. U of T professors Lakshmi Kotra, Cecil Yip, Peter Ottensmeyer and Robert Batey have created the first small molecules using the three-dimensional structure of the insulin receptor. A receptor is the site on the surface of a cell to which molecules with specific tasks, such as hormones, attach themselves. Insulin's task is to initiate the utilization of sugar in the blood.

26 Mar 2004

Supercomputer used to determine structures and functions of proteins

Scientists at the U.S. Department of Energy’s Brookhaven National Laboratory are proposing to use a supercomputer originally developed to simulate elementary particles in high-energy physics to help determine the structures and functions of proteins, including, for example, the 30,000 or so proteins encoded by the human genome. Structural information will help scientists better understand proteins’ role in disease and health, and may lead to new diagnostic and therapeutic agents.

26 Mar 2004

Researchers turn off individual human genes to study their function

Researchers have produced vast libraries of short segments of ribonucleic acid (RNA) that can be used to turn off individual human and mouse genes to study their function. The libraries will be made widely available to laboratories studying human biology and disease. The researchers are optimistic that the libraries will become a powerful research tool for gene analysis and discovery.

25 Mar 2004

Stenting for Stroke Prevention is More Effective Than Surgery in Keeping Blood Vessels Open

Research presented in a six-hour symposium on carotid artery disease at the 29th Annual Scientific Meeting of the Society of Interventional Radiology showed carotid artery stenting to be safe and effective for highrisk patients. Currently, the standard of care for stroke prevention in patients with moderate to severely blocked carotid arteries is carotid endarterectomy surgery. The ARCHeR trials treated patients who were high-risk surgical candidates with carotid artery stenting with and without embolic protection, a device to capture debris that may break off during the procedure.

25 Mar 2004

New Research Information on Tumor Necrosis Therapy

Researchers for Peregrine Pharmaceuticals presented today at the Strategic Research Institute’s Clinical-Stage Product Partnering Summit in La Jolla, CA a summary of clinical experience with Tumor Necrosis Therapy (TNT). The TNT technology is being developed in the U.S. and Europe by Peregrine under the trade name Cotara™. Over 200 patients have been treated with TNT world-wide and a TNT product has been approved to treat grade III or IV advanced lung cancer in the People’s Republic of China. A Cotara registration study for brain cancer has been approved by the U.S. Food and Drug Administration, and a Phase I colorectal cancer study is on-going at Stanford University Medical Center.

25 Mar 2004

Discovery of new gene sheds light on human brain development

With the identification of the gene responsible for a newly recognized type of mental retardation, researchers at Beth Israel Deaconess Medical Center (BIDMC) have also discovered what appears to be the key target in the evolution of the frontal lobes of the brain's cerebral cortex. The findings offer a key insight into the complex puzzle of human brain development - and the evolution of human behavior.

25 Mar 2004

Breakthrough studies that could lead to a new means of combating malaria

EMBL scientists have identified four mosquito proteins that affect the ability of the malaria parasite (Plasmodium) to survive and develop in the malaria-carrier mosquito (Anopheles). This breakthrough could be used to block the transmission of malaria from mosquitoes to humans.

25 Mar 2004

Scientists have taken a significant leap forward in understanding the complex ways that molecules work together in cells.

Although scientists already know a lot about single molecules, they know very little about how they are assembled into larger molecular complexes or "machines" and how these machines work together to create a complete, functioning cell. The problem is like trying to assemble a puzzle with billions of pieces– with only the shapes of some pieces to go on.

25 Mar 2004

Brain signals could act as remote controls

In their first human studies of the feasibility of using brain signals to operate external devices, researchers at Duke University Medical Center report that arrays of electrodes can provide useable signals for controlling such devices. The research team is now working to develop prototype devices that may enable paralyzed people to operate "neuroprosthetic" and other external devices using only their brain signals.

25 Mar 2004

Alcohol boosts the pleasurable effects of nicotine

In tests on human volunteers, Duke University Medical Center researchers have found that even small amounts of alcohol boost the pleasurable effects of nicotine, inducing people to smoke more when drinking alcoholic beverages. The findings provide a physiological explanation for the common observation that people smoke more in bars. The findings also explain statistics showing that alcoholics tend to smoke more than non-alcoholics, and that smokers are more likely to be alcoholics.

24 Mar 2004

Bone marrow stem cells do not help regenerate heart muscle tissue, UW study finds, contradicting earlier study

Researchers at the University of Washington School of Medicine have found that bone marrow stem cells do not convert into heart muscle cells in mice. These results contradict a study conducted elsewhere that had prompted human clinical trials for such stem cell therapy in the treatment of heart attack.

23 Mar 2004

Medical Research News

Simple blood tests which could predict the severity of osteoarthritis

Program to help health-carers reduce hospital falls by up to 30%

Halting the development of certain pancreatic, ovarian, colon and lung cancers may be possible with new therapy

A simple dietary supplement may also help to prevent strokes

Haemophilia Society President presents Hepatitis C (HCV) Facts to UK Government

£35m needed to boost M.E./Chronic Fatigue Syndrome research

Researchers have successfully grafted human breast tissue into the mammary glands of mice

p53 protein peptide stops cancer in its tracks

A common antibiotic used to treat arthritis and acne shows promise for limiting the severity of spinal cord and brain injuries

Oral medication for diabetes a step closer

Supercomputer used to determine structures and functions of proteins

Researchers turn off individual human genes to study their function

Stenting for Stroke Prevention is More Effective Than Surgery in Keeping Blood Vessels Open

New Research Information on Tumor Necrosis Therapy

Discovery of new gene sheds light on human brain development

Breakthrough studies that could lead to a new means of combating malaria

Scientists have taken a significant leap forward in understanding the complex ways that molecules work together in cells.

Brain signals could act as remote controls

Alcohol boosts the pleasurable effects of nicotine

Bone marrow stem cells do not help regenerate heart muscle tissue, UW study finds, contradicting earlier study

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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