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Study highlights potential of genomic tests for early stage prostate cancer

A new review led by researchers at Moffitt Cancer Center assessed how three genomic tests - Decipher, Oncotype DX Genomic Prostate Score (GPS) and Prolaris - can help doctors make better decisions about how to treat patients with early stage prostate cancer.

24 Jan 2025

Study offers new insight into how nature and nurture shape aggression in males

Like humans, mice will compete over territory and mates, and show increased confidence in their fighting skills the more they win.

24 Jan 2025

Crick researchers identify key Y chromosome genes influencing sperm development

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice.

23 Jan 2025

Strong heart, strong bones: How cardiovascular health influences bone density

Higher cardiovascular health (Life’s Essential 8 scores) is linked to greater bone mineral density in adults aged 20–59, with stronger associations in younger individuals, women, and those with normal BMI, suggesting heart-healthy habits may protect bone strength.

22 Jan 2025

Social but lonely? The emotional challenges of highly sensitive people

Highly Sensitive Persons (HSPs) experience greater emotional loneliness due to their deep need for meaningful relationships, but their social interactions are similar to the general population.

22 Jan 2025

Global research uncovers varying diabetes mortality risks by ethnicity

While advances in diabetes care have improved survival rates, this study highlights persistent ethnic disparities in mortality risk, urging tailored healthcare strategies to address diverse needs.

22 Jan 2025

OncoAssure announces clinical validation of prostate cancer test

OncoAssure Ltd, an Irish medical diagnostic company, today announced the publication of new data, in the British Journal of Urology International Compass (BJUI Compass), which demonstrates the clinical validation of OncoAssure Prostate, a novel biopsy test which provides improved estimation of a patient’s risk of prostate cancer recurrence and allows for optimal treatment selection.

21 Jan 2025

Expert consensus provides unified framework for prostate cancer care in China

While prostate cancer is becoming more prevalent among middle-aged and elderly men in China, clinical practice still faces considerable challenges due to the lack of unified guidelines and high-level evidence on several aspects of patient care.

20 Jan 2025

Exploring the use of genomic classifier tests in prostate cancer risk stratification

A systematic review found that while genomic classifier (GC) tests may influence risk classifications or treatment decisions for patients with localized prostate cancer (PCa), there is a need for better data on their cost-effectiveness, clinical utility, and their impact on racial and ethnic groups, particularly Black men.

20 Jan 2025

Air pollution amplifies dementia risk in cardiometabolic disease patients - healthy habits can help

CMD patients face a 2x higher risk of dementia and MCI, but healthier lifestyles can counter air pollution's impact and reduce these risks.

16 Jan 2025

Study unveils role of TLE6 in male sperm development

Infertility is a major global challenge associated with physiological and psychological impact. Genetic mutations that affect early embryonic development, oocyte (egg cell) maturation, and fertilization have recently been studied as causes of infertility.

16 Jan 2025

Could mulberry extract be the key to fighting obesity-induced reproductive dysfunction?

Research indicates mulberry extract's efficacy in addressing obesity-related male infertility, enhancing reproductive outcomes through bioactive compounds.

16 Jan 2025

Morning coffee cuts health risks, but all-day sipping doesn’t

Moderate morning coffee consumption may lower all-cause and cardiovascular mortality risks, but coffee consumed throughout the day offers no similar benefits.

13 Jan 2025

Australia sees a decline in type 2 diabetes, but disparities persist

Type 2 diabetes incidence in Australia decreased from 2010 to 2019 overall but rose among younger men and specific ethnic groups, highlighting persistent disparities.

13 Jan 2025

Teens face body image crisis as social media fuels dissatisfaction globally

Study investigates body dissatisfaction among youth in six countries, revealing strong associations with social media use and sociodemographics, emphasizing a global need for interventions.

12 Jan 2025

Mortality risks soar with ultra-processed foods - simple diet changes can help

Ultra-processed food consumption increases mortality risks, particularly from circulatory, digestive diseases, and Parkinson's, but substituting minimally processed foods can lower these risks.

12 Jan 2025

Being fit matters more than weight for long-term health, research shows

Cardiorespiratory fitness significantly reduces mortality risks regardless of BMI, highlighting fitness as a critical health determinant over weight loss strategies.

12 Jan 2025

Analysis highlights high TBI death rates among older adults and men

A new analysis of U.S. mortality data reveals the disproportionate impact of traumatic brain injuries (TBI) on older adults, males and certain racial and ethnic groups.

10 Jan 2025

RNA nanoparticles offer dual action against prostate tumors

Yang Zhang, PhD, and Jinjun Shi, PhD, both of the Center for Nanomedicine and Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women's Hospital, are co-senior authors of a paper published in ACS Nanoscience Au, "Lipid Nanoparticle Delivery of mRNA and siRNA for Concurrent Restoration of Tumor Suppressor and Inhibition of Tumorigenic Driver in Prostate Cancer."

10 Jan 2025