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A survey of 371,000 adults links heart disease to eating whole fruit less often

In a survey analysis of 371,038 US adults, those reporting high blood pressure, high cholesterol, a heart attack, or coronary heart disease ate whole fruit slightly less often than those without the respective conditions. After adjustment, 100% fruit-juice consumption was less frequent among adults with high cholesterol and more frequent among those reporting a heart attack, but the cross-sectional study cannot establish cause and effect.

28 Sep 2026

Why one gut microbe is attracting attention in heart failure research

Researchers found that chronic systolic heart failure caused by nonischemic cardiomyopathy was associated with reduced gut microbial diversity, depletion of Bifidobacterium, and lower microbial short-chain fatty acid production potential. Higher Bifidobacterium abundance and higher circulating indole-3-propionic acid levels were associated with milder disease and clinical improvement, although the findings do not establish causality.

27 Sep 2026

$Hypofractionated radiotherapy for prostate cancer matches conventional treatment outcomes$

Hypofractionated radiotherapy for prostate cancer matches conventional treatment outcomes

Men with high-risk prostate cancer have a higher likelihood of having residual disease following prostatectomy and may require radiation therapy after surgery, particularly when PSA levels begin to rise. Conventional postprostatectomy radiotherapy (COPORT) is typically delivered over 37 fractions, while hypofractionated postprostatectomy radiotherapy (HYPORT) delivers a slightly lower total radiation dose over just 25 fractions.

27 Sep 2026

Could the Mediterranean diet protect the brain through the gut?

A narrative review finds that the Mediterranean diet may support brain health through gut microbiome, immune, metabolic, and barrier-related pathways, but direct human evidence that microbiome remodeling mediates neuroprotection remains limited. The proposed mechanisms involve microbial metabolites, reduced inflammatory signaling, stronger intestinal and blood-brain barrier function, and possible effects on processes linked to Alzheimer’s and Parkinson’s diseases.

27 Sep 2026

Heated tobacco users had more hypertension, but the story is not that simple

A large Japanese real-world cohort study found that current heated tobacco product users had a higher risk of developing hypertension than never-smokers in the primary adjusted analysis. However, the association weakened in several sensitivity analyses, and the observational study could not separate the effects of current heated tobacco use from previous cigarette exposure.

27 Sep 2026

Could age help explain why psychedelic studies reach different conclusions?

A cross-sectional study of 1,088 adults found that lifetime classic psychedelic use was associated with lower current anxiety and depression symptoms among younger adults, but these associations weakened with age. Mystical experiences may partly explain the age-related pattern, although the observational design cannot establish that psychedelic use caused the mental health differences.

27 Sep 2026

Researchers find how prostate tumors reshape the immune microenvironment

Researchers at The University of Texas MD Anderson Cancer Center have identified a previously unknown pathway that prostate tumors leverage to suppress the immune system by reshaping the tumor microenvironment to resist treatment.

25 Sep 2026

Intuitive eating may be linked to more than a healthier relationship with food

A cross-sectional study of 1,057 U.S. adults examined how intuitive eating relates to stress, sleep, physical activity, substance use, diet, self-rated health, and self-reported cardiometabolic conditions. Higher intuitive eating scores were associated with several favorable health indicators, although the study cannot establish causality or determine the direction of these relationships.

25 Sep 2026

Neuromedin U drives immune suppression in aggressive prostate cancer

A new study from The Wistar Institute has found a link between the nervous system and the rapid development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease.

24 Sep 2026

Why are more younger adults in the Eastern Mediterranean facing colorectal cancer?

A 22-country analysis of modeled GLOBOCAN 2022 data found 15,381 early-onset colorectal cancer cases and 6,965 related deaths across the WHO Eastern Mediterranean Region, with substantial differences between countries and comparatively high mortality. Projections suggest that annual case and death counts could rise markedly by 2050, largely due to demographic change, while the findings support screening and detection strategies tailored to local resources and disease burden.

24 Sep 2026

The heart effects of antidepressants may depend as much on the patient as the drug

Antidepressants differed in their effects on QTc, with amitriptyline and escitalopram producing small average increases, and the magnitude of changes varying according to individual patient characteristics. The trials did not detect an increase in early major cardiovascular events or non-suicidal sudden death, but they were not large or long enough to rule out rare or later cardiovascular events.

24 Sep 2026

Beetroot juice may make swimming feel easier without making swimmers faster

A systematic review and meta-analysis of 12 studies, with nine contributing data from 120 swimmers, found no significant improvement in swimming time-trial performance or post-exercise blood lactate with beetroot juice or dietary nitrate supplementation. Supplementation produced a small reduction in perceived exertion, but the effect varied across studies, and the certainty of evidence for swimming performance was low.

24 Sep 2026

Happy at work, better at the job? A study of young employees offers clues

Researchers studying 412 employees aged 35 or younger in Spain found that higher job satisfaction was associated with better task and contextual performance. Work that negatively affected mental health and personal life was associated with poorer contextual performance and more counterproductive behavior, while supervisor emotional accessibility and organizational respect showed no significant direct links to performance.

24 Sep 2026

Frailty linked to greater cognitive impairment risk in men with chronic kidney disease

New research from the University of Colorado Anschutz Department of Medicine is shedding light on how women and men with chronic kidney disease (CKD) may fare differently as they age and their disease progresses.

23 Sep 2026

Feeling lonely at work? How often you see your colleagues may matter

In a nationally representative sample of 7,798 employees in Germany aged 25 to 65, about 26% reported lacking companionship from colleagues, 17% felt excluded, and 8% felt lonely at work at least sometimes. Less frequent direct contact with colleagues was consistently associated with all three facets of workplace loneliness, although the cross-sectional study cannot establish cause and effect.

23 Sep 2026

Cancer-related DNA changes may appear in blood years before diagnosis

Researchers found that genome-wide plasma cfDNA methylation profiles collected before diagnosis contained early molecular signatures associated with future prostate and breast cancer, with prostate silencer methylation providing the stronger risk stratification. Breast enhancer signals were weaker and varied by subtype and disease stage, indicating that cfDNA methylation may have greater value for risk assessment and surveillance than as a standalone diagnostic test.

23 Sep 2026

What links smoking, body fat, mental health, genes, and heart risk? Inflammation may be part of the answer

In a large UK Biobank study, higher levels of the chronic inflammation marker GlycA were associated with smaller heart chambers, thicker heart walls, impaired diastolic function, reduced stroke volume, and a 43% higher risk of major adverse cardiovascular events in the highest versus lowest GlycA group. Genetic susceptibility also modified the associations between environmental exposures, inflammation, and cardiovascular risk, while inflammatory proteins in the IL-1, TNF, and IL-6 pathways statistically mediated several of these associations.

23 Sep 2026

Regular exercisers show distinct metabolic and immune signatures in blood

Researchers compared blood samples from 40 regular exercisers and 46 sedentary adults and found differences in metabolites, blood chemistry, and immune cell gene activity. The patterns suggested greater fatty acid use and altered immune signaling among exercisers, but the study could not establish that exercise caused these differences.

21 Sep 2026

Several cups of coffee a day showed no clear diabetes link over 10 years

Researchers followed 1,158 adults in Italy for 10 years, comparing those who drank at least two to three cups of coffee daily with those who drank none. They found no statistically significant difference in new cases of impaired fasting glucose or type 2 diabetes, but the small non-consumer group limits how confidently the study can rule out a difference in risk.

21 Sep 2026

Looking for GLP-1 advice online? Likes may tell you less than you think

Researchers assessed 128 videos about GLP-1 medications on Douyin and Bilibili and found that Bilibili videos scored higher on two measures of reliability and transparency. Longer videos received higher quality scores, while popularity did not consistently reflect information quality.

21 Sep 2026