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SBRT improves bowel health related quality-of-life in patients with localized intermediate-risk prostate cancer

Results of the NRG Oncology NRG-GU005 clinical study comparing stereotactic body radiation therapy (SBRT) to moderately hypofractionated intensity-modulated radiation therapy (MH-IMRT) for patients with localized intermediate risk prostate cancer indicate that the use of SBRT improved bowel health related quality of life (HRQOL) in this patient population.

25 Aug 2026

What decades of wine research can, and cannot, tell us about health

A narrative review found that moderate wine intake has repeatedly been associated with lower all-cause and cardiovascular mortality, with proposed mechanisms involving ethanol and grape-derived polyphenols, but the evidence remains largely observational and cannot establish causation. The authors argue that drinking pattern, beverage type, age, cancer risk, and risk-modeling choices all influence how the J-shaped association should be interpreted and how alcohol guidelines are developed.

25 Aug 2026

From caffeine to trigonelline, coffee has surprising links to muscle biology

A scoping review of 54 studies found that coffee and several coffee-derived bioactive compounds influence pathways linked to skeletal muscle metabolism, including insulin signaling, mitochondrial function, oxidative stress, inflammation, glucose uptake, and protein turnover. Human studies reported associations with greater muscle mass and lower frailty or functional impairment, but most evidence remains observational or preclinical and cannot establish causality.

25 Aug 2026

The diet-Alzheimer’s connection is more complicated than “eat this, avoid that”

A mini-review finds that dietary patterns may influence Alzheimer’s disease through interconnected pathways involving neuroinflammation, insulin resistance, oxidative stress, blood-brain barrier dysfunction, homocysteine, and the gut-brain axis. The authors argue that genetics, sex, age, physical activity, and socioeconomic context may modify these relationships, supporting more individualized approaches to nutrition research and dementia prevention.

25 Aug 2026

An 11-year study found the same social media pattern again and again

Across 11 annual U.S. surveys involving about 183,000 adults, higher social media use was consistently associated with self-reported depression, with social media ranking among the strongest predictors in machine-learning models. SHAP analyses suggested that social media use became a stronger positive signal for depression at around 150 minutes per day, although the authors stress that this is not an established clinical threshold and requires longitudinal and experimental testing.

24 Aug 2026

Could a daily vinegar drink help with constipation? A small trial offers a clue

A randomized, double-blind trial found that adults with mild constipation who drank a vinegar beverage daily for four weeks had more frequent bowel movements than those receiving placebo. Exploratory findings also suggested earlier improvements in bowel habits, although the small feasibility-based trial requires confirmation in larger and more diverse populations.

24 Aug 2026

These simple fitness tests revealed which older adults had the lowest death risk

Objective fitness tests in 13,423 Taiwanese adults aged 65 years or older linked better balance, agility, lower-body strength, and cardiorespiratory fitness with lower all-cause mortality over a median seven years. A multidomain fitness index showed the strongest association, suggesting that simple performance tests may add useful information to conventional geriatric risk assessment.

24 Aug 2026

A two-year diet trial challenges the idea that weight loss is the only result that matters

In the two-year DELISH randomized trial, adults with obesity achieved modest, sustained weight loss with either an adapted Mediterranean-style program or a commercial weight loss program. The Mediterranean-style intervention produced greater improvements in self-reported diet quality, while 24-month weight loss did not materially differ between groups.

24 Aug 2026

A striking immune cell pattern emerges around a person’s 100th birthday

Single-cell immune profiling found that CD4 cytotoxic T lymphocytes become more abundant around age 100, showing stepwise differentiation and substantial clonal expansion. Ex vivo experiments also revealed cytokine plasticity within individual clones, supporting the hypothesis that these cells adapt to persistent antigens during healthy aging, although their direct role in longevity remains unproven.

23 Aug 2026

Sprinters and non-athletes had similar gut diversity, but one key difference emerged

College sprint athletes showed a distinct gut microbial community structure, including higher abundance of Segatella copri and Bifidobacterium adolescentis, compared with non-athletic students. Their microbiomes also showed predicted enrichment of carbohydrate and amino acid metabolism pathways, while exploratory analyses linked several dietary factors with the signature bacteria.

20 Aug 2026

What happens to your diet when you get better at cooking?

Cooking-skills interventions were associated with healthier dietary behaviors in healthy adults, including greater fruit and vegetable intake, improved diet quality, and greater cooking confidence. However, the certainty of evidence was low to very low, and too little evidence was available to determine whether cooking skills affect nutritional status.

20 Aug 2026

Study shows how prostate tumors rewire metabolism to resist therapy

Prostate tumors can rewire amino acid metabolism to override the normal brakes on cholesterol production, a process that may fuel hormone therapy resistance, according to a study by Weill Cornell Medicine investigators.

20 Aug 2026

This 29-year heart study tracked what happens after smokers quit

Long-term data from the Copenhagen City Heart Study linked both current and former smoking with a higher risk of sudden cardiac death, with risk rising alongside cumulative smoking exposure. Among former smokers, risk generally declined with longer time since quitting and approached that of never smokers only after prolonged abstinence.

20 Aug 2026

More coffee, higher testosterone? This study found a more complicated picture

Higher habitual coffee intake was associated with a leaner body composition, lower circulating branched-chain amino acids, and distinct cardiometabolic patterns in 2,264 middle-aged Finnish adults. Hormonal associations differed by sex, with broader testosterone- and SHBG-related patterns in men and more limited SHBG-related changes in women.

20 Aug 2026

A single blood test could offer a glimpse of disease risk years in advance

Machine learning-derived cellular aging clocks mapped more than 7,000 plasma proteins to over 40 cell types, revealing marked differences in how individual cell populations age. These blood-based signatures were associated with future risks of Alzheimer’s disease, ALS, lung cancer, type 2 diabetes, and mortality across follow-up extending to 15 years.

19 Aug 2026

Paternal valproate use not linked to offspring neurodevelopmental risks

Use of the antiseizure drug valproate by fathers before conception is not associated with neurodevelopmental disorders like autism or attention-deficit/hyperactivity disorder (ADHD) in their children, according to a new study published August 19, 2026, in Neurology®, an official journal of the American Academy of Neurology.

19 Aug 2026

Immediate access puts test results in patients’ hands, but the next challenge is making sense of them

A nationally representative US study found that 68.6% of adults with access to medical records viewed immediately released test results before hearing from a healthcare practitioner. Among these viewers, only 34.9% rated their understanding as very good, with comprehension varying by region, digital literacy, patient-centered communication, and experiences of medical care discrimination.

19 Aug 2026

A decades-long study raises questions about sugary drinks and stomach cancer

A large prospective U.S. study followed more than 111,000 adults to examine whether sugar-sweetened and artificially sweetened beverage intake was associated with gastric cancer incidence. Researchers identified 278 gastric cancer cases over 3.2 million person-years and found that associations differed according to beverage type and level of consumption.

19 Aug 2026

What 3,600 adults with diabetes revealed about lifestyle and heart health

In 3,612 British adults with type 2 diabetes, greater adherence to the Mediterranean Lifestyle Index was associated with lower risks of major adverse cardiovascular events, cardiovascular death, and all-cause mortality over more than a decade of follow-up. Dietary patterns, physical activity, rest, and social habits all contributed to the observed associations, although the observational study cannot establish causality.

19 Aug 2026

What a 38-year study suggests about red meat, white meat, and mortality

Lower intake of red and processed meat was associated with small reductions in all-cause, heart disease, cancer, and stroke mortality in a cohort of nearly one million US adults followed for decades. White-meat-only diets showed additional benefits in some subgroups, while vegetarian diets produced few consistent associations and were limited by small participant numbers and a single baseline dietary assessment.

18 Aug 2026