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New test can pinpoint which people with gonorrhea can be cured with ciprofloxacin

A test designed by UCLA researchers can pinpoint which people with gonorrhea will respond successfully to the inexpensive oral antibiotic ciprofloxacin, which had previously been sidelined over concerns the bacterium that causes the infection was becoming resistant to it.

7 Aug 2020

Study: Inhaled sedatives can reduce lung inflammation, improve survival

A team from Lawson Health Research Institute are being funded by the Government of Ontario's COVID-19 Rapid Research Fund to study whether inhaled sedatives can replace those that are delivered intravenously in COVID-19 patients requiring ventilation.

6 Aug 2020

New protocol reduces opioid use following surgery

The majority of patients who followed an "Enhanced Recovery After Surgery" (ERAS) protocol did not need opioids for pain management at multiple time points following elective spinal and peripheral nerve surgery.

6 Aug 2020

RPS calls for community pharmacists to be allowed to alter prescriptions

The Royal Pharmaceutical Society is calling for all community pharmacists to be allowed to make changes to prescriptions that would reduce unnecessary delays in providing medicines to patients if the item prescribed was in short supply or out of stock.

6 Aug 2020

Study: UnityPhilly app can help fight America's opioid crisis

Equipped with naloxone and a smartphone app, community members can save lives in the fight against America's opioid crisis, according to a paper from researchers at Drexel University's Dornsife School of Public Health and colleagues published this week in The Lancet journal EClinicalMedicine.

6 Aug 2020

Medicare Part D insurance plans largely favor generics over brand-name drugs

Contrary to previous media reports, a new study led by Vanderbilt University Medical Center researchers finds that Medicare Part D prescription drug insurance plans largely favor generic drugs over brand-name counterparts.

5 Aug 2020

European Commission approves first drug for hepatitis D

What started off as basic research 25 years ago has now lead to a successfully approved drug: The entry blocker bulevirtide (brand name Hepcludex, formerly known as Myrcludex B), jointly developed by researchers from Heidelberg University Hospital (UKHD) and the Medical Faculty of Heidelberg, the DZIF and other partners, has now been approved by the European Commission.

5 Aug 2020

NICE guideline advises GPs to stop prescribing opioids for chronic pain

Published today, the first ever NICE guideline on the treatment of chronic pain has said that GPs should not prescribe opioids and other medicines like paracetamol to patients because they could be ‘harmful’ and cause addiction.

5 Aug 2020

HPV vaccination reduces risk of cervical cancer

Vaccination against the human papilloma virus (HPV) reduces the risk of a condition that often leads to cervical cancer, according to an analysis of Danish health registry data.

5 Aug 2020

Neutrolis announces development of first-in-class therapy to target NETs in COVID-19 patients

Neutrolis, a biotechnology company developing therapeutics that target neutrophils, the most abundant immune cells in the body, today announced the development of NTR-441, a first-in-class DNASE1L3 enzyme analog that has the potential to rapidly and systemically clear neutrophil extracellular traps for severe cases of COVID-19.

5 Aug 2020

Pharmacists look at deprescribing to reduce the risk of medicine-related harm

In an article published today in Australian Prescriber, pharmacist Michelle Liacos from Alfred Health in Melbourne, and her co-authors, look at stopping medicines when they are no longer needed to reduce the risk of medicine-related harm.

5 Aug 2020

Study shows link between selenium-deficient diet and paracetamol toxicity

A lack of the mineral selenium in the diet puts people at risk of paracetamol overdose, even when the painkiller is taken at levels claimed to be safe on the packaging, according to collaborative research emerging from the University of Bath and Southwest University in China.

5 Aug 2020

New computational model can help determine drug viability

About 50% of people who take the drug infliximab for inflammatory bowel diseases, such as Crohn's disease, end up becoming resistant or unresponsive to it.

5 Aug 2020

DSI introduces new, hands-on opportunity for drug sponsors to learn from CMC and regulatory subject matter experts

Design Space InPharmatics, an Industry Leader in Regulatory Drug Development, today announced its latest innovative offering for emerging biotech drug sponsors.

From DSI, a PLG Company 4 Aug 2020

Non-adherence to prescription medicines is more common in younger U.S women

For patients, especially those living with chronic conditions, nonadherence to prescription medicines due to cost is a common problem.

4 Aug 2020

Artificial intelligence can increase effectiveness of drug repurposing for psychiatric disorders

Artificial intelligence can increase the effectiveness of drug repositioning or repurposing research, according to a study published in Translational Psychiatry.

3 Aug 2020

Darolutamide shows indication of considerable added benefit in prostate cancer

Up to now, adult men with non-metastatic castration-resistant prostate cancer (nmCRPC) at high risk of developing metastatic disease usually continued their conventional androgen deprivation therapy (ADT) while the cancer was observed for the occurrence of metastases (so-called watchful waiting).

3 Aug 2020