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Silibinin: An old molecule with new promise in cancer treatment

A new review paper was published in Oncotarget's Volume 15 on May 23, 2024, entitled, "The importance of integrated therapies on cancer: Silibinin, an old and new molecule."

28 May 2024

Novel coating in antipsychotics mitigates unwanted weight gain and boosts serotonin levels

Thousands of Australians struggle with serious mental health conditions. But when the recommended treatment involves antipsychotic medications, the side effects are excess kilos, which only adds weight to an already complex diagnosis.

28 May 2024

Taking semaglutide once weekly may lower the chances of kidney disease, says study

The effects of semaglutide (administered once weekly) on the outcomes of kidney disease.

28 May 2024

Increased risk of erectile dysfunction with semaglutide in non-diabetic obese patients

Researchers found that semaglutide treatment for weight loss in non-diabetic, obese men is associated with an increased risk of erectile dysfunction and testosterone deficiency.

26 May 2024

New understanding of cancer drug's ability to prevent fat buildup in the liver

University of Oklahoma researchers have deepened their understanding of a drug's ability to prevent fat buildup in the liver, a condition that often occurs with obesity and can lead to serious fatty liver disease.

23 May 2024

Tailoring polymeric micelles for improved olaparib solubility and drug release

Olaparib is a selective poly (ADP-ribose) polymerase inhibitor. However, its clinical application is hindered by low solubility and undesired pharmacokinetic profiles (e.g., relatively short circulation).

23 May 2024

Clomiphene and dexamethasone boost fertility in PCOS patients

Combined clomiphene and dexamethasone treatment improves pregnancy and ovulation rates in PCOS patients, with minimal adverse effects. Further research is needed to optimize dosage and duration.

22 May 2024

Dupilumab shows promise in cutting COPD flare-ups and boosting lung function

Dupilumab significantly reduces exacerbations and improves lung function in COPD patients with elevated eosinophil counts, confirming the efficacy of targeting type 2 inflammation.

22 May 2024

Sharp uptick in youth using wegovy and ozempic, study reports

Public interest in weight loss drugs like Wegovy and Ozempic is surging, but national data on dispensing patterns in the United States are surprisingly scarce.

22 May 2024

High price of popular diabetes drugs deprives low-income people of effective treatment

For the past year and a half, Tandra Cooper Harris and her husband, Marcus, who both have diabetes, have struggled to fill their prescriptions for the medications they need to control their blood sugar.

21 May 2024

Fake news unmasked: Emotional features boost fake news detection accuracy on social media

Researchers found that integrating emotional features, particularly negative emotions, into machine learning models enhances the accuracy of fake news detection on social media platforms. This study highlights the crucial role of emotions in distinguishing between real and fake news during the COVID-19 pandemic.

20 May 2024

Treating obesity using glucagon-like peptide-1-directed N-methyl-D-aspartate receptor inhibition

Bimodal drug that successfully cures obesity, hyperglycemia, and dyslipidemia in mouse models.

20 May 2024

Metformin use linked to reduced risk of myeloproliferative neoplasms

People who use metformin are less likely to develop a myeloproliferative neoplasm (MPN) over time, indicating that the treatment may help prevent the development of certain types of cancers, according to a study published in Blood Advances.

17 May 2024

Pre-vaccine COVID-19: US study reveals hospitalization rate of 5.7% and fatality rate of 1.7%

Study estimates COVID-19 hospitalization and mortality rates in the US during the pre-vaccination period, revealing significant age and racial disparities in outcomes.

17 May 2024

Chiropractic care reduces tramadol prescriptions for sciatica, study finds

A new study led by researchers at University Hospitals Connor Whole Health found that adults initially receiving chiropractic spinal manipulation for newly diagnosed radicular low back pain (sciatica) were significantly less likely to be prescribed tramadol over the following year compared to those receiving usual medical care.

16 May 2024

Research highlights complexity of xylazine and fentanyl combination in overdose cases

Unregulated use of fentanyl and overdose deaths have increased dramatically in recent years, and this trend was made more alarming when authorities found fentanyl laced with the animal tranquilizer xylazine.

16 May 2024

$Blood pressure medications associated with higher fracture risk among nursing home residents$

Blood pressure medications associated with higher fracture risk among nursing home residents

Records from nearly 30,000 nursing home residents indicate that blood pressure medications more than double the risk of life-threatening bone fractures, according to Rutgers Health research.

16 May 2024

New guideline issued for antiseizure medication use in pregnant epilepsy patients

A new guideline has been issued to help neurologists and other clinicians determine the best antiseizure medications for people with epilepsy who may become pregnant.

16 May 2024

Closed Loop Medicine and Pharmanovia commence OptiZest study for their first precision medicine combination therapeutic

Closed Loop Medicine Ltd, a leading TechBio company developing combination prescription drug plus software therapy products that deliver personalized dose optimization, and Pharmanovia, a global pharmaceutical company that commercializes novel medicines and revitalizes, extends and expands the lifecycle of established medicines, today announced the initiation of their OptiZest study, ID: NCT06372470, and first patient recruitment.

From Closed Loop Medicine 16 May 2024

Anti-obesity medications slash heart disease risk in obese patients, study finds

A study in the journal Obesity evaluated the impact of new anti-obesity medications (AOMs) on cardiovascular disease (CVD) among obese individuals, finding that these medications reduce the risk of CVD complications, particularly heart failure and atrial fibrillation.

15 May 2024

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Pharmaceutical News

Silibinin: An old molecule with new promise in cancer treatment

Novel coating in antipsychotics mitigates unwanted weight gain and boosts serotonin levels

Taking semaglutide once weekly may lower the chances of kidney disease, says study

Increased risk of erectile dysfunction with semaglutide in non-diabetic obese patients

New understanding of cancer drug's ability to prevent fat buildup in the liver

Tailoring polymeric micelles for improved olaparib solubility and drug release

Clomiphene and dexamethasone boost fertility in PCOS patients

Dupilumab shows promise in cutting COPD flare-ups and boosting lung function

Sharp uptick in youth using wegovy and ozempic, study reports

High price of popular diabetes drugs deprives low-income people of effective treatment

Fake news unmasked: Emotional features boost fake news detection accuracy on social media

Treating obesity using glucagon-like peptide-1-directed N-methyl-D-aspartate receptor inhibition

Metformin use linked to reduced risk of myeloproliferative neoplasms

Pre-vaccine COVID-19: US study reveals hospitalization rate of 5.7% and fatality rate of 1.7%

Chiropractic care reduces tramadol prescriptions for sciatica, study finds

Research highlights complexity of xylazine and fentanyl combination in overdose cases

Blood pressure medications associated with higher fracture risk among nursing home residents

New guideline issued for antiseizure medication use in pregnant epilepsy patients

Closed Loop Medicine and Pharmanovia commence OptiZest study for their first precision medicine combination therapeutic

Anti-obesity medications slash heart disease risk in obese patients, study finds

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