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Comprehensive study highlights effectiveness and limitations of ADHD treatments in adults

Findings indicate stimulants and atomoxetine effectively reduce ADHD symptoms, though non-pharmacological therapies show potential for long-term efficacy.

20 Dec 2024

Annona squamosa extracts show promise in treating pain and arthritis

In Brazil, researchers have identified substances with analgesic, anti-inflammatory, anti-hyperalgesic (against persistent pain) and anti-arthritic activity in the leaves of Annona squamosa, a tree popularly known in the country as fruta-do-conde or pinha.

20 Dec 2024

Review highlights gaps in reporting quality of nonpharmacological treatments in Chinese medicine

Nonpharmacological treatments in Chinese medicine (NPTCM), including acupuncture, cupping, moxibustion, and Tuina, have gained global recognition for their efficacy in various health conditions.

20 Dec 2024

Breastfeeding after COVID-19 vaccination is safe, with minimal changes to milk composition

This study reveals how SARS-CoV-2 infection significantly alters human milk composition, while COVID-19 vaccination causes minimal, transient changes, underscoring the safety of breastfeeding during vaccination.

19 Dec 2024

Sunscreen prototype keeps skin cooler and shields from UV rays

Wearing sunscreen is important to protect your skin from the harmful effects of UV radiation but doesn't cool people off.

19 Dec 2024

Combining psychedelics with meditation increases mindfulness and mystical-type transcendence

Researchers assessed whether combining psychedelics, namely DMT and harmine as two active ingredients in ayahuasca, with meditation increases mindfulness, compassion, insight, and mystical-type transcendence to a higher degree than meditation with a placebo.

19 Dec 2024

MS medications do not increase pregnancy risks, research shows

An analysis of over 3,700 pregnancies of women with multiple sclerosis indicates that the therapy doesn’t lead to increased risks of miscarriage, premature birth or serious birth defects.

18 Dec 2024

New study reveals complex attitudes toward psychedelic therapy

In a comprehensive Genomic Press Interview with researchers from Emory University, a new study published today reveals complex attitudes toward psychedelic therapy, with detailed statistics showing both strong support for potential benefits and significant awareness of risks.

18 Dec 2024

How a duty to spend wisely on worker benefits could loosen PBMs’ grip on drug prices

Ann Lewandowski knows all about pharmacy benefit managers, or PBMs, the companies that shape the U.S. drug market. Her job, as a policy advocate at drugmaker Johnson & Johnson, was to tell patient and physician groups about the PBMs' role in high drug prices.

18 Dec 2024

Revolutionizing MASLD treatment with GLP-1 receptor agonists

Researchers explore the therapeutic potential and clinical insights of GP1-RAs in the management of metabolic dysfunction-associated steatotic liver disease.

16 Dec 2024

Research finds no change in mortality despite platinum chemotherapy shortage

During a shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin that began in early 2023, there was no difference in mortality rates among patients with advanced cancer compared to the previous year, and prescription rates for the two drugs fell less than three percent overall - and 15.1 percent at the peak - according to an analysis published this week in the Journal of the National Cancer Institute by researchers from the University of Pennsylvania's Perelman School of Medicine and Penn Medicine's Abramson Cancer Center.

14 Dec 2024

Zeqi exhibits multifunctional therapeutic potential in modern medicine

Announcing a new publication for Acta Materia Medica journal. Zeqi (Euphorbia helioscopia L.), is a widely distributed plant of the Euphorbiaceae family.

13 Dec 2024

Insilico Medicine gets first clinical milestone payment of $10 million for XL309

Insilico Medicine ('Insilico'), a clinical-stage generative artificial intelligence (AI)-driven drug discovery and development company, today announced that it has received the first clinical milestone payment of $10 million for XL309 (previously known as ISM3091) from Exelixis.

12 Dec 2024

Repeated paracetamol use linked to health risks in older adults

New research, led by experts at the University of Nottingham, has found that repeated doses of paracetamol in people aged 65 and over, can lead to an increased risk of gastrointestinal, cardiovascular and renal complications.

12 Dec 2024

Addressing inequities in cardiovascular drug access

A new study assessing provincial and territorial variations in reimbursement criteria of drug coverage for patients covered by Canada's public pharmacare programs for two common cardiovascular conditions revealed significant inequities and deficiencies in access to medications and treatment.

12 Dec 2024

New tool accelerates drug discovery

The development of molecules to study and treat disease is becoming increasingly burdened by the time and specificity required to analyze the vast amounts of data generated by synthesizing large collections of new molecules.

12 Dec 2024

Mayo Clinic researchers advocate for comprehensive TPMT genotyping across ancestries

Mayo Clinic researchers found that a gene variant, the TPMT∗8 allele, is associated with reduced metabolism of the thiopurine class of drugs. TPMT∗8 is relatively common in individuals of African or African American descent. A novel study in The Journal of Molecular Diagnostics, published by Elsevier, details the researchers' goal to provide pharmacogenomic testing that can be used clinically to predict drug response that is beneficial to all patients, regardless of their ancestral background.

11 Dec 2024

The brain’s hunger switch: TRH neurons hold the key to obesity therapies

Scientists uncover how TRH neurons suppress hunger by inhibiting AgRP neurons, advancing our understanding of GLP-1-based obesity treatments.

9 Dec 2024

Minoxidil found safe and effective for hair loss in breast cancer patients

Hair loss during chemotherapy can cause enough distress for some women to lose self-confidence, which experts say may discourage them from seeking chemotherapy in the first place.

9 Dec 2024

Filgotinib offers new promise for managing Crohn’s disease

Filgotinib, a JAK1 preferential inhibitor, shows promise as an effective and well-tolerated maintenance therapy for Crohn's disease, achieving clinical and endoscopic remission in phase 3 trials. The findings highlight its potential as a novel therapeutic option for difficult-to-treat patients.

8 Dec 2024