Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Grand Challenges Canada funds 15 new projects to improve mental health diagnosis and care

Grand Challenges Canada, which is funded by the Government of Canada, today announced a landmark $19.4 million in support of 15 innovative, pioneering projects designed to improve mental health diagnosis and care in developing countries, many of them nations ravaged by conflict and disaster as well as poverty.

11 Oct 2012

Stroke on the rise among young people

New research reveals that stroke may be affecting people at a younger age. The study is published in the October 10, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

11 Oct 2012

Leading scientists select first drugs to be evaluated in Alzheimer's clinical study

Leading scientists have selected the first drugs to be evaluated in a worldwide clinical study to determine whether they can prevent Alzheimer's disease.

11 Oct 2012

New drug candidate improves cognitive function of rats with Alzheimer's-like mental impairment

Washington State University researchers have developed a new drug candidate that dramatically improves the cognitive function of rats with Alzheimer's-like mental impairment.

11 Oct 2012

Researchers identify astrocytes as new target for Alzheimer's

Alzheimer's disease is a severe neurodegenerative disease that affects 45% of people over 85 years of age. The research teams of Prof. Jin-Moo Lee at Washington University in Saint Louis, USA, and Prof. Milos Pekny at Sahlgrenska Academy in Gothenburg, Sweden, have identified astrocytes as a novel target for the development of future treatment strategies. The results have just been published in the FASEB Journal.

10 Oct 2012

Study compares gene expression levels in two key hippocampal regions affected by Alzheimer's

Researchers from the Computational Intelligence Group based at the Universidad Politécnica de Madrid's Facultad de Informática have used machine learning and data mining techniques to compare gene expresssion levels in Alzheimer's disease (AD) patients in two key regions of the hippocampus: the dentate gyrus, where the disease appears to have little or no effect, and the entorhinal cortex, where Alzheimer's disease produces major neuronal damage.

10 Oct 2012

Grp94 chaperone protein can interfere with clearance of myocilin from cells

The chaperone protein Grp94 can interfere with the clearance of another protein known to cause the glaucoma when mutated, a new study led by researchers at the University of South Florida has found. Using a cell model, the researchers also demonstrated that a new specific inhibitor of Grp94 facilitates clearance of the genetically-defective protein, called myocilin, from cells.

10 Oct 2012

RMND1 gene mutations responsible for severe neurodegenerative disorders

Scientists at the Montreal Neurological Institute and Hospital - The Neuro, McGill University working with a team at Oxford University have uncovered the genetic defect underlying a group of rare genetic disorders.

10 Oct 2012

Lilly announces detailed results from solanezumab Phase 3 trials on Alzheimer's

Eli Lilly and Company today announced its detailed results for the Phase 3, double-blind, placebo-controlled EXPEDITION studies in patients with mild-to-moderate Alzheimer's disease.

9 Oct 2012

Navigating the Labyrinth of Traumatic Brain Injury to Discover a Secondary Neurological Condition

Working with individuals with traumatic brain injury (TBI) every day, I see the debilitating effects and long-term struggles firsthand.

9 Oct 2012

Eating tomatoes associated with reduced risk of stroke

Eating tomatoes and tomato-based foods is associated with a lower risk of stroke, according to new research published in the October 9, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology. Tomatoes are high in the antioxidant lycopene.

9 Oct 2012

Scientists discover how protein deficiency may be linked to frontotemporal dementia

Using animal models, scientists at the Gladstone Institutes have discovered how a protein deficiency may be linked to frontotemporal dementia (FTD)-a form of early-onset dementia that is similar to Alzheimer's disease. These results lay the foundation for therapies that one day may benefit those who suffer from this and related diseases that wreak havoc on the brain.

9 Oct 2012

Low-dose aspirin may protect against cognitive decline in elderly women

Elderly women at risk for cardiovascular events who take low-dose acetylsalic acid exhibit less cognitive decline on the Mini Mental State Examination than their peers who do not take the drug, report researchers.

8 Oct 2012

Alzheimer's disease diagnosis within minutes using a simple brain scan

Groundbreaking research taking place at the University of York could lead to Alzheimer's disease being diagnosed in minutes using a simple brain scan.

8 Oct 2012

Scientists discover process by which vitamin B12 is made in cells

In a development that may lead to new drugs to treat cancer, scientists at the University of Kent have discovered the process by which a key vitamin (B12) is made in cells.

8 Oct 2012

Study provides direct evidence for persistent activity in medial entorhinal cortex layer neurons

UCLA researchers have for the first time measured the activity of a brain region known to be involved in learning, memory and Alzheimer's disease during sleep. They discovered that this part of the brain behaves as if it's remembering something, even under anesthesia, a finding that counters conventional theories about memory consolidation during sleep.

8 Oct 2012

Rember revamped for Phase 3 testing in behavioral-variant frontotemporal dementia

Rember—the blue dye that created a stir in 2008 when Phase 2 clinical trial data claimed that it slowed decline in people with Alzheimer's disease—has now been revamped for Phase 3 testing in another disease, behavioral-variant frontotemporal dementia (bvFTD).

6 Oct 2012

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Grand Challenges Canada funds 15 new projects to improve mental health diagnosis and care

Stroke on the rise among young people

Leading scientists select first drugs to be evaluated in Alzheimer's clinical study

New drug candidate improves cognitive function of rats with Alzheimer's-like mental impairment

Researchers identify astrocytes as new target for Alzheimer's

Study compares gene expression levels in two key hippocampal regions affected by Alzheimer's

Grp94 chaperone protein can interfere with clearance of myocilin from cells

RMND1 gene mutations responsible for severe neurodegenerative disorders

Lilly announces detailed results from solanezumab Phase 3 trials on Alzheimer's

Navigating the Labyrinth of Traumatic Brain Injury to Discover a Secondary Neurological Condition

Eating tomatoes associated with reduced risk of stroke

Scientists discover how protein deficiency may be linked to frontotemporal dementia

Low-dose aspirin may protect against cognitive decline in elderly women

Alzheimer's disease diagnosis within minutes using a simple brain scan

Scientists discover process by which vitamin B12 is made in cells

Study provides direct evidence for persistent activity in medial entorhinal cortex layer neurons

Rember revamped for Phase 3 testing in behavioral-variant frontotemporal dementia

Researchers from three trials join to collaborate under European Dementia Prevention Initiative

Benzodiazepine exposure for over-65s linked to increased risk of dementia

People with difficulty in chewing foods more likely to develop dementia

eBook: Neurodegeneration Therapeutics Discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Neurodegeneration Therapeutics Discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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