Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Acetylcholine can weaken synaptic connections between neurons in brain

Researchers from the University of Bristol have discovered that a chemical compound in the brain can weaken the synaptic connections between neurons in a region of the brain important for the formation of long-term memories.

14 Dec 2011

Link between high tau levels and worse outcome after head trauma

High levels of tau protein in fluid bathing the brain are linked to poor recovery after head trauma, according to a study from Washington University School of Medicine in St. Louis and the Fondazione IRCCS Ca Granda-Ospedale Maggiore Policlinico in Milan, Italy.

14 Dec 2011

GW scientist to identify molecular mechanisms that define embryonic OE stem cells

Anthony-Samuel LaMantia, PhD, professor in the Department of Pharmacology and Physiology and Director of the GW Institute for Neuroscience in the School of Medicine and Health Sciences has been awarded a grant from the National Institutes of Health to identify molecular mechanisms that define embryonic olfactory epithelium (OE) stem cells.

14 Dec 2011

Brain atrophy is evident in Parkinson's patients with MCI

Atrophy in the hippocampus, the region of the brain known for memory formation and storage, is evident in Parkinson's disease (PD) patients with cognitive impairment, including early decline known as mild cognitive impairment (MCI), according to a study by researchers in the Perelman School of Medicine at the University of Pennsylvania.

13 Dec 2011

Intertwined diseases may both contribute to cognitive decline in Parkinson's

A method of classifying brain atrophy patterns in Alzheimer's disease patients using MRIs can also detect cognitive decline in Parkinson's disease, according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania. Researchers also found that higher baseline Alzheimer's patterns of atrophy predicted long-term cognitive decline in cognitively normal Parkinson's patients.

13 Dec 2011

Study describes new method that synthesizes novel anti-HIV protein

The most abundant and important molecules in all living organisms are proteins; after all they manage to participate in every single one of life's essential reactions. So it is easy to see why scientists have been making such a fuss trying to learn how to synthesise them in laboratory as this would provide them with a tool of extraordinary potential. Unfortunately, this has not proved easy.

13 Dec 2011

Roundup: Iowans question Wellmark premium hikes; Fla. Medicare audit; Mich. nursing home scandals

The Wellmark Blue Cross/Blue Shield vice president faced dozens of angry customers and tried to explain why the health insurer wants to increase their premiums by 9.4 percent. ... Barbed questions flew throughout the hearing before the state insurance commissioner, who will decide whether to grant Wellmark's proposed increase for 86,000 Iowans who buy their own insurance policies.

13 Dec 2011

Alzheimer’s disease vaccine developed by Australian scientists

Scientists from the University of Sydney on Saturday have announced that they have developed a vaccine to help halt the progression of Alzheimer's disease of humans. The progress of neurodegenerative condition affects more than 35 million people worldwide.

12 Dec 2011

New method to design Alzheimer's antibodies

Researchers at Rensselaer Polytechnic Institute have developed a new method to design antibodies aimed at combating disease. The surprisingly simple process was used to make antibodies that neutralize the harmful protein particles that lead to Alzheimer's disease.

12 Dec 2011

Tips to help ease caregiver's burden during holiday season

More five million Americans suffer from Alzheimer's disease or another form of dementia and over 70 percent of those individuals are cared for in their homes by a spouse or other family member. Stress, anxiety and burnout are never far from the doorsteps of these caregivers as they often juggle the responsibilities of providing daily care with the added demands of working, maintaining a household, or raising children. The holiday season can intensify these daily burdens, but too often caregivers don't know how to ask for help and friends and family members aren't sure of how to lend a hand.

9 Dec 2011

Ovary removal in younger women may lead to low-bone mineral density, arthritis

Having both ovaries removed before age 45 is strongly associated with low-bone mineral density and arthritis in later years, according to a new study by Johns Hopkins oncologists and epidemiologists. The analysis covered several thousand women who took part in a U.S. government-sponsored, multiyear national health study, and excluded women whose ovaries were removed due to cancer.

9 Dec 2011

Pharmacyclics, Janssen partner to develop and market PCI-32765 anti-cancer compound

Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, announced today that it has executed an agreement with Pharmacyclics, Inc. to jointly develop and market the anti-cancer compound, PCI-32765.

9 Dec 2011

Pending budget cuts could jeopardize health, safety of state's most vulnerable seniors

California's low-income seniors with disabilities are struggling to remain in their homes as public funding for long-term care services shrinks and may be slashed even further, according to a new study by the UCLA Center for Health Policy Research conducted with support from The SCAN Foundation.

8 Dec 2011

MS may progress from outermost layers of brain to its deep parts

Multiple sclerosis (MS) may progress from the outermost layers of the brain to its deep parts, and isn't always an "inside-out" process as previously thought, reported a new collaborative study from researchers at the Mayo Clinic and the Cleveland Clinic.

8 Dec 2011

Animal study offers insights into possible drug targets to improve memory as we age

Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study in the December 7 issue of The Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.

8 Dec 2011

Israeli Nobel Laureate receives AvH's Humboldt Research Award

The Israeli Nobel Laureate Aaron Ciechanover has been named one of the recipients of the Humboldt Research Award of the Alexander von Humboldt Foundation.

8 Dec 2011

Alzheimer’s vaccine cures memory of mice

A vaccine that slows the progression of Alzheimer’s disease and other types of dementia has been developed by researchers at the University of Sydney’s Brain and Mind Research Institute (BMRI).

7 Dec 2011

Next generation personal genomic testing now widely available

The era of widely available next generation personal genomic testing has arrived and with it the ability to quickly and relatively affordably learn the sequence of your entire genome. This would include what is referred to as the "exome," your complete set of protein-coding sequences.

7 Dec 2011

Web-based video game players contribute to analysis of DNA sequences

Thousands of video game players have helped significantly advance our understanding of the genetic basis of diseases such as Alzheimer's, diabetes and cancer over the past year. They are the users of a web-based video game developed by Dr. J-r-me Waldispuhl of the McGill School of Computer Science and collaborator Mathieu Blanchette.

7 Dec 2011

Circadian activity rhythm linked to subsequent development of dementia or MCI

Older women with weaker circadian rhythms, who are less physically active or are more active later in the day are more likely to develop dementia or mild cognitive impairment than women who have a more robust circadian rhythm or are more physically active earlier in the day. That's the finding of a new study in the latest issue of the Annals of Neurology.

7 Dec 2011