Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Study finds novel site within MS4A gene cluster, confirms presence of SNP linked with Alzheimer's

Recently the number of genes known to be associated with Alzheimer's disease has increased from four to eight, including the MS4A gene cluster on chromosome 11.

31 May 2011

Small noncoding RNA spurs Alzheimer's development

Researchers pinpoint a small RNA that spurs cells to manufacture a particular splice variant of a key neuronal protein, potentially promoting Alzheimer's disease or other types of neurodegeneration.

31 May 2011

Stress does not appear to increase risk of developing multiple sclerosis

Contrary to earlier reports, a new study finds that stress does not appear to increase a person's risk of developing multiple sclerosis. The research is published in the May 31, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

31 May 2011

Pre-implantation genetic diagnosis can avoid mother to child transmission of mtDNA disorders

Dutch researchers have developed a test which predicts which mothers at risk of passing on mitochondrial genetic disease to their children are likely to have a healthy baby.

30 May 2011

Stem cell pluripotency depends on E-cadherin molecule

Researchers of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch have discovered what enables embryonic stem cells to differentiate into diverse cell types and thus to be pluripotent. This pluripotency depends on a specific molecule - E-cadherin - hitherto primarily known for its role in mediating cell-cell adhesion as a kind of "intracellular glue".

27 May 2011

NIH awards $2.4 million, five-year grant for research on dementia and delirium

Adults with dementia and delirium may soon have a way to combat their delirium, thanks to a $2.4 million, five-year grant from the National Institutes of Health.

27 May 2011

Karolinska researchers study four siblings affected by early-onset Alzheimer's disease

Four siblings in a family affected by early-onset Alzheimer's have been studied by a group of researchers at Karolinska Institutet in Sweden. This has been a unique opportunity to make comparative studies and to monitor the development of the disease over a prolonged period of time.

27 May 2011

NILVAD consortium awarded €6 million grant to develop new Alzheimer's disease treatment

An international research consortium led by Trinity College Dublin that aims to develop a new Alzheimer's disease treatment has just been selected for grant funding of €6 million by the European Commission Seventh Framework Programme (FP7).

27 May 2011

Lactate shuttle also exists in human tumors

Researchers at the Kimmel Cancer Center at Jefferson have shed new light on the longstanding conundrum about what makes a tumor grow-and how to make it stop. Interestingly, cancer cells accelerate the aging of nearby connective tissue cells to cause inflammation, which ultimately provides "fuel" for the tumor to grow and even metastasize.

27 May 2011

Researchers find mechanism of action for cancer-killing peptides

Researchers from Aalto University have found the mechanism of action for cancer-cell-killing peptides. This breakthrough is expected to lead to better medication, in particular better treatments for leukemia, skin cancer, and infections caused by multi-resistant bacteria.

27 May 2011

Naturally occurring plant alkaloids could help prevent, delay memory loss linked with Alzheimer's

A family of naturally occurring plant compounds could help prevent or delay memory loss associated with Alzheimer's disease, according to a new study by the Translational Genomics Research Institute.

27 May 2011

Study: Stress may trigger Alzheimer's disease

Stress promotes neuropathological changes that are also seen in Alzheimer's disease. Scientists from the Max Planck Institute of Psychiatry in Munich have discovered that the increased release of stress hormones in rats leads to generation of abnormally phosphorylated tau protein in the brain and ultimately, memory loss.

27 May 2011

Study links decrease in U.S. workplace physical activity with obesity epidemic

In a new study conducted at the Pennington Biomedical Research Center, scientists have found that the decrease in workplace physical activity over the past fifty years is a significant contributor to the obesity epidemic.

26 May 2011

Researchers propose 'advance directives' for driving

Researchers studying driving habits and accident rates among the elderly found a majority surveyed supported mandatory retesting of drivers based on age while saying they would hand over the keys if a doctor or loved one said they were no longer fit to drive.

26 May 2011

Recycling protein molecules could lead to new therapies for Alzheimer's disease

The formation of abnormal strands of protein called amyloid fibrils - associated with two dozen diseases ranging from Alzheimer's to type-2 diabetes - may not be permanent and irreversible as previously thought, scientists are reporting in the Journal of the American Chemical Society.

26 May 2011

Non-invasive trigeminal nerve stimulation shows promise in controlling seizures

Medications are the mainstay of treatment for epilepsy, but for a considerable number of patients - estimated to be as many as 1 million in the U.S. - drugs don't work. These patients suffer from a type of epilepsy known as refractory or drug-resistant epilepsy, in which drugs can't control their seizures.

26 May 2011

Study to examine whether red wine component could help reduce concussions in pro boxers

UT Southwestern Medical Center researchers are engaging the help of professional boxers and trainers to study whether a component in red wine and grapes could help reduce the short- and long-term effects of concussions.

26 May 2011

New findings from STELARA psoriasis clinical trial to be presented at 22nd World Congress of Dermatology

New findings to be presented from pooled analyses of the STELARA psoriasis clinical development program showed that the safety profile of STELARA and rates of adverse events remained consistent and stable over time in adults with moderate to severe plaque psoriasis receiving up to four years of treatment.

25 May 2011

Elan, Proteostasis create innovative drug discovery initiative for neurodegenerative disorders

Proteostasis Therapeutics and Elan Corporation today announced a strategic business relationship to advance Proteostasis' platform for the discovery and development of disease-modifying, small molecule drugs and diagnostics for the treatment of neurodegenerative disorders such as Parkinson's, Huntington's, multiple sclerosis and amyotrophic lateral sclerosis, and a broad array of dementia-related diseases including Alzheimer's.

25 May 2011

Leukemia protein plays a role in Alzheimer's disease

After decades of studying the pathological process that wipes out large volumes of memory, scientists at The Feinstein Institute for Medical Research discovered a molecule called c-Abl that has a known role in leukemia also has a hand in Alzheimer's disease.

25 May 2011

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Study finds novel site within MS4A gene cluster, confirms presence of SNP linked with Alzheimer's

Small noncoding RNA spurs Alzheimer's development

Stress does not appear to increase risk of developing multiple sclerosis

Pre-implantation genetic diagnosis can avoid mother to child transmission of mtDNA disorders

Stem cell pluripotency depends on E-cadherin molecule

NIH awards $2.4 million, five-year grant for research on dementia and delirium

Karolinska researchers study four siblings affected by early-onset Alzheimer's disease

NILVAD consortium awarded €6 million grant to develop new Alzheimer's disease treatment

Lactate shuttle also exists in human tumors

Researchers find mechanism of action for cancer-killing peptides

Naturally occurring plant alkaloids could help prevent, delay memory loss linked with Alzheimer's

Study: Stress may trigger Alzheimer's disease

Study links decrease in U.S. workplace physical activity with obesity epidemic

Researchers propose 'advance directives' for driving

Recycling protein molecules could lead to new therapies for Alzheimer's disease

Non-invasive trigeminal nerve stimulation shows promise in controlling seizures

Study to examine whether red wine component could help reduce concussions in pro boxers

New findings from STELARA psoriasis clinical trial to be presented at 22nd World Congress of Dermatology

Elan, Proteostasis create innovative drug discovery initiative for neurodegenerative disorders

Leukemia protein plays a role in Alzheimer's disease

eBook: Hallmarks of Neurodegeneration eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Hallmarks of Neurodegeneration eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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