Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Nutrient 'biomarkers' may help assess nutrient status of elderly people at risk for dementia

Research is trying to determine whether Alzheimer's disease might be slowed or prevented with nutritional approaches, but a new study suggests those efforts could be improved by use of nutrient "biomarkers" to objectively assess the nutrient status of elderly people at risk for dementia.

24 Jan 2011

PenTAG research plays pivotal role in NICE decision to extend availability of Alzheimer's disease drugs

A review of research evidence produced by researchers from the Peninsula Technology Assessment Group, part of the Peninsula College of Medicine and Dentistry, has played a pivotal role in the decision by the National Institute for Health and Clinical Excellence (NICE) to extend the availability of donepezil, galantamine, rivastigmine and memantine for Alzheimer's disease announced on 18th January 2011.

21 Jan 2011

Math may help assess how rapidly stem cells and cancer-causing cousins increase numbers

The difficult task of sorting and counting prized stem cells and their cancer-causing cousins has long frustrated scientists looking for new ways to help people who have progressive diseases.

21 Jan 2011

NGOs, IAOMT urge to ban mercury-containing products, including dental amalgam

Mercury, the main ingredient in "silver" or amalgam fillings, will be the subject of a United Nations conference to be held in Chiba, Japan on January 24-28. Members of various non-governmental organizations, as well as dentists and scientists from groups such as the International Academy of Oral Medicine and Toxicology, will be attending and urging a ban on products containing mercury, including dental amalgam.

21 Jan 2011

Repligen enters exclusive license agreement with UCI for use of HDAC3 inhibitors for memory disorders

Repligen Corporation announced today that it has entered into an exclusive license agreement with the University of California, Irvine (UCI) for a patent application covering the use of histone deacetylase 3 (HDAC3) inhibitors for the treatment of disorders involving preservation or extinction of memory including Alzheimer's disease, memory impairment and post traumatic stress disorder.

21 Jan 2011

Cognition Therapeutics closes $2.5 million Series A1 financing

Cognition Therapeutics Inc., a drug discovery company developing novel, small molecule disease-modifying treatments for Alzheimer's, has closed on a $2.5 million Series A1 financing it will use to bring one or more of its compounds to Investigational New Drug (IND) candidate status. The round was led by Golden Seeds, one of the nation's largest angel investing groups, and was syndicated with Tech Coast Angels.

20 Jan 2011

Scientists discover fundamental mechanism behind toxic protein aggregation in neurodegenerative diseases

Protein aggregation underlies several neurodegenerative diseases such as Alzheimer's, Huntington's chorea or Parkinson's. Scientists at the Max Planck Institute of Biochemistry (MPIB) in Martinsried near Munich, Germany, now discovered a fundamental mechanism which explains how toxic protein aggregation occurs and why it leads to a widespread impairment of essential cellular functions.

20 Jan 2011

Brains of migraine sufferers show higher proportion of lesions of brain microvessels

Recent work, in particular the CAMERA study, has used MRI to study the brains of migraine sufferers and has shown that a higher proportion of these patients exhibit lesions of the brain microvessels than the rest of the population.

20 Jan 2011

Delaying onset of Alzheimer's disease by 10 years could potentially eliminate the disease completely

The combined results of a genetic blood test and a five-minute functional MRI successfully classified more than three-quarters of healthy older adults, many of whom were destined to develop cognitive decline within 18 months of testing.

20 Jan 2011

New research: HIV individuals are more likely to have stroke

New research suggests that people infected with human immunodeficiency virus may be up to three times more likely to have a stroke compared to those not affected with HIV. The study is published in the January 19, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

20 Jan 2011

Positive top-line results from TC-5619 Phase 2 trial in patients with schizophrenia

Targacept, Inc. today announced positive top-line results from a Phase 2 clinical proof of concept trial to assess TC-5619 as an augmentation therapy to improve cognition in patients with schizophrenia.

20 Jan 2011

Salk Institute uncovers presenilin's productive side

Mutant presenilin is infamous for its role in the most aggressive form of Alzheimer's disease-early-onset familial Alzheimer's-which can strike people as early as their 30s. In their latest study, researchers at the Salk Institute uncovered presenilin's productive side: It helps embryonic motor neurons navigate the maze of chemical cues that pull, push and hem them in on their way to their proper targets.

19 Jan 2011

Alternative interventions do just as well as cognitive interventions for reducing 'senior moments'

Trying to stave off senior moments with memory drills and similar brain-boosting activities? A new evidence review suggests that these specific training regimes are not any better than simple conversations at improving memory in older adults.

19 Jan 2011

Deep brain stimulation stabilizes motor symptoms in Parkinson's disease over time

Parkinson's disease symptoms begin subtly and worsen as damage to certain brain cells continues. But an electrical stimulation device implanted deep in the brain and programmed remotely, along with medications, may provide some control of "motor symptoms" common to the disease, such as shaking, stiffness, and loss of muscle control.

19 Jan 2011

Lower levels in plasma of biomarkers beta-amyloid 42/40 increase rate of cognitive decline

Older adults without dementia and with lower levels in plasma of the biomarkers beta-amyloid 42/40 (protein fragments) had an increased rate of cognitive decline over a period of 9 years, according to a study in the January 19 issue of JAMA. The researchers also found that this relationship was stronger among individuals with less education and lower levels of literacy.

19 Jan 2011

Molecular imaging procedure may detect beta-amyloid in brain, increase accuracy of AD diagnosis

Preliminary research suggests that use of a type of molecular imaging procedure may have the ability to detect the presence of beta-amyloid in the brains of individuals during life, a biomarker that is identified during autopsy to confirm a diagnosis of Alzheimer disease, according to a study in the January 19 issue of JAMA.

19 Jan 2011

Study: Brain's 'autopilot' network may aid in early diagnosis of Alzheimer's disease

Watching the brain's "autopilot" network in real time may help determine the onset of cognitive decline and potentially aid in making an early diagnosis of Alzheimer's disease, according to researchers at Duke University Medical Center.

19 Jan 2011

MicroRNA-29 molecule makes brain cells resistant to programmed cell death

Researchers at the University of North Carolina at Chapel Hill have discovered a molecule that can make brain cells resistant to programmed cell death or apoptosis.

19 Jan 2011

Forest Laboratories third quarter net sales increase 6.7% to $1,063.9 million

Forest Laboratories, Inc., an international pharmaceutical manufacturer and marketer, announced that reported earnings per share equaled $1.11 in the third quarter of fiscal 2011 after taking a charge for a new product licensing fee of $66.1 million or $0.23 per share, net of tax.

18 Jan 2011

Biological Psychiatry publishes special issue focusing on postmortem studies of psychosis

Biological Psychiatry is proud to announce this week's publication of a special issue focusing on postmortem studies of psychosis. This special issue showcases the use of human brains postmortem to study psychiatric disorders, focusing on schizophrenia. The review articles highlight the benefits, achievements, problems, and perhaps most importantly, the future of postmortem research.

18 Jan 2011

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Nutrient 'biomarkers' may help assess nutrient status of elderly people at risk for dementia

PenTAG research plays pivotal role in NICE decision to extend availability of Alzheimer's disease drugs

Math may help assess how rapidly stem cells and cancer-causing cousins increase numbers

NGOs, IAOMT urge to ban mercury-containing products, including dental amalgam

Repligen enters exclusive license agreement with UCI for use of HDAC3 inhibitors for memory disorders

Cognition Therapeutics closes $2.5 million Series A1 financing

Scientists discover fundamental mechanism behind toxic protein aggregation in neurodegenerative diseases

Brains of migraine sufferers show higher proportion of lesions of brain microvessels

Delaying onset of Alzheimer's disease by 10 years could potentially eliminate the disease completely

New research: HIV individuals are more likely to have stroke

Positive top-line results from TC-5619 Phase 2 trial in patients with schizophrenia

Salk Institute uncovers presenilin's productive side

Alternative interventions do just as well as cognitive interventions for reducing 'senior moments'

Deep brain stimulation stabilizes motor symptoms in Parkinson's disease over time

Lower levels in plasma of biomarkers beta-amyloid 42/40 increase rate of cognitive decline

Molecular imaging procedure may detect beta-amyloid in brain, increase accuracy of AD diagnosis

Study: Brain's 'autopilot' network may aid in early diagnosis of Alzheimer's disease

MicroRNA-29 molecule makes brain cells resistant to programmed cell death

Forest Laboratories third quarter net sales increase 6.7% to $1,063.9 million

Biological Psychiatry publishes special issue focusing on postmortem studies of psychosis

eBook: Hallmarks of Neurodegeneration eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Hallmarks of Neurodegeneration eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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