Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

UH physicists study workings of PGK enzyme that may cause Alzheimer's, cancer

University of Houston physicists are using complex computer simulations to illuminate the workings of a crucial protein that, when malfunctioning, may cause Alzheimer's and cancer.

20 Nov 2010

NJISA experts to discuss science, impact and current state of Alzheimer's disease in America

The New Jersey Institute for Successful Aging (NJISA) at the UMDNJ-School of Osteopathic Medicine, one of the country's leading providers of geriatric care, research and education, is making experts available who can discuss the science, impact and current state of Alzheimer's disease in America.

20 Nov 2010

Anavex closes private placement and issued securities

Anavex Life Sciences Corp. announces that it closed a private placement and issued securities to settle debt owed by the Company.

20 Nov 2010

Physical activity may protect high-risk individuals from cognitive decline: Study

Physical activity promotes changes in the brain that may protect high-risk individuals against cognitive decline, including development of Alzheimer's disease, according to a new study done at the University of Wisconsin-Milwaukee (UWM).

19 Nov 2010

Study compares effect on HT status in mid, late life on dementia risk

Compared to women never on hormone therapy, those taking hormone therapy only at midlife had a 26 percent decreased risk of dementia; while women taking HT only in late life had a 48 percent increased risk of dementia, according to Kaiser Permanente researchers.

19 Nov 2010

Mass. regulators and nursing homes fight inappropriate medicating; officials deal with Hawaii doctor shortage

State regulators and the Massachusetts nursing home industry are launching a campaign today to reduce the inappropriate use of antipsychotic medications for residents with dementia.

19 Nov 2010

Pericyte cells become key players in shaping blood flow in the brain

Cells in the brain called pericytes that have not been high on the list of targets for treating diseases like Alzheimer's may play a more crucial role in the development of neurodegenerative diseases than has been realized.

18 Nov 2010

OSEO awards €10.4 million to DIPPAL project targeting Alzheimer's disease

The biotech companies PHARNEXT and BIOSYSTEMS INTERNATIONAL, the Bordeaux Hospital where CMRR is located, the university Bordeaux Segalen and Inserm (the center U897 "Epidemiology and Biostatistics") have joined forces to carry out the DIPPAL2i project. This innovative research and industrial development project is targeting Alzheimer's disease (AD) and has attracted significant financial support from OSEO (the French state innovation agency).

18 Nov 2010

New findings identify Sortilin as a potential therapeutic site to alter PGRN pathology in dementia

Frontotemporal lobar degeneration (FTLD) refers to a group of disorders associated with degeneration of the frontal and temporal lobes of the brain. Symptoms include dementia, aphasia, and semantic disorders.

18 Nov 2010

Multiple sclerosis drug shows promise to counteract effects of botulinum neurotoxin

Scientists are reporting that variants of a drug already approved for treating multiple sclerosis show promise as a long sought treatment for victims of bioterrorist attack with botulinum neurotoxin which is 10,000 times deadlier than cyanide and the most poisonous substance known to man.

18 Nov 2010

Anti-cancer drug smuggled using a nanocarrier past protective blood-brain barrier into brain tumours

Scientists in Germany have developed a way of smuggling an anti-cancer drug past the protective blood-brain barrier and into brain tumours and metastases using a nanocarrier - a tiny capsule specially designed to pass through cell membranes and deliver its anti-cancer drug to the cancer cell.

18 Nov 2010

DiaGenic receives 92,738,974 shares in subsequent offering

Preliminary counts indicate that DiaGenic has received subscriptions for approximately 92,738,974 shares in the subsequent offering closed yesterday.

18 Nov 2010

Naurex's antidepressant shares efficacy mechanisms with NMDA receptor antagonist ketamine

Naurex Inc., a company developing innovative treatments to address unmet needs in psychiatry and neurology, today reported that data presented at Neuroscience 2010 show that GLYX-13, its clinical-stage candidate for the treatment of depression, shares key mechanistic features associated with the antidepressant efficacy of the NMDA receptor antagonist ketamine.

18 Nov 2010

State-of-the-art imaging system helps locate and count myriad connections between brain nerve cells

Researchers at the Stanford University School of Medicine, applying a state-of-the-art imaging system to brain-tissue samples from mice, have been able to quickly and accurately locate and count the myriad connections between nerve cells in unprecedented detail, as well as to capture and catalog those connections' surprising variety.

18 Nov 2010

Researchers find clue behind dementia development

Researchers at the Mayo Clinic campus in Florida have found a clue as to how some people develop a form of dementia that affects the brain areas associated with personality, behavior, and language.

18 Nov 2010

Cigarette smoke, automobile exhaust and french fries increase risk of developing Alzheimer's disease

There is growing evidence that exposure to a group of chemicals known as type-2 alkenes -- which are found in the smoke inhaled from cigarettes, the exhaust of automobiles and even in French fries - can increase the chances of developing Alzheimer's disease and other neurological conditions such as Parkinson's disease.

18 Nov 2010

Neuralstem files NSI-189 IND with FDA for Phase I safety trials for major depression

Neuralstem, Inc. announced that it has filed an Investigational New Drug (IND) application with the United States Food and Drug Administration (FDA) to begin two Phase I safety trials to test NSI-189, its first small molecule compound, for the treatment of major depression. NSI-189 is a proprietary new chemical entity discovered by Neuralstem that stimulates new neuron growth in the hippocampus, an area of the brain that is believed to be involved in depression.

18 Nov 2010

5-lipoxygenase protein modulates amyloid beta formation linked to Alzheimer's disease

A protein known to exist in the brain for more than 30 years, called 5-lipoxygenase, has been found to play a regulatory role in the formation of the amyloid beta in the brain, the major component of plaques implicated in the development of Alzheimer's disease, according to researchers at Temple University's School of Medicine.

18 Nov 2010

Imec and PEIRA develop platform for in-vitro study of brain tissue

The nanoelectronics research centre imec and Peira, a Belgium-based manufacturer of pharmaceutical and chemical research instruments, jointly developed an innovative slice-tilting instrument for in-vitro research on brain tissue. The new tool enables long-term studying of brain cultures through electronic stimulation and read-out, essential in getting insight into the functioning of the brain.

17 Nov 2010

New slice-tilting instrument for in-vitro research on brain tissue

17 Nov 2010

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

UH physicists study workings of PGK enzyme that may cause Alzheimer's, cancer

NJISA experts to discuss science, impact and current state of Alzheimer's disease in America

Anavex closes private placement and issued securities

Physical activity may protect high-risk individuals from cognitive decline: Study

Study compares effect on HT status in mid, late life on dementia risk

Mass. regulators and nursing homes fight inappropriate medicating; officials deal with Hawaii doctor shortage

Pericyte cells become key players in shaping blood flow in the brain

OSEO awards €10.4 million to DIPPAL project targeting Alzheimer's disease

New findings identify Sortilin as a potential therapeutic site to alter PGRN pathology in dementia

Multiple sclerosis drug shows promise to counteract effects of botulinum neurotoxin

Anti-cancer drug smuggled using a nanocarrier past protective blood-brain barrier into brain tumours

DiaGenic receives 92,738,974 shares in subsequent offering

Naurex's antidepressant shares efficacy mechanisms with NMDA receptor antagonist ketamine

State-of-the-art imaging system helps locate and count myriad connections between brain nerve cells

Researchers find clue behind dementia development

Cigarette smoke, automobile exhaust and french fries increase risk of developing Alzheimer's disease

Neuralstem files NSI-189 IND with FDA for Phase I safety trials for major depression

5-lipoxygenase protein modulates amyloid beta formation linked to Alzheimer's disease

Imec and PEIRA develop platform for in-vitro study of brain tissue

New slice-tilting instrument for in-vitro research on brain tissue

eBook: Neurodegeneration Therapeutics Discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Neurodegeneration Therapeutics Discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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