Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Shorter telomere length of leucocytes may signal heightened dementia risk

Shorter telomeres on the ends of white blood cell chromosomes may signal a heightened dementia risk, suggest the results of a large long term study, published online in the journal General Psychiatry.

12 Sep 2023

Unlocking the future of dementia: Your telomere length could predict your risk

The recent study in General Psychiatry found that leukocyte telomere length (LTL) is significantly associated with the risk of developing dementia, especially Alzheimer's disease. Using data from over 430,000 individuals, the study suggests that telomere length could serve as a predictive biomarker for brain health and dementia risk.

12 Sep 2023

Sedentary behavior linked to increased risk of dementia in adults over 60

Adults aged 60 and older who spend more time engaging in sedentary behaviors like sitting while watching TV or driving may be at increased risk of developing dementia, according to a new study by USC and University of Arizona researchers.

12 Sep 2023

Scientists develop new method to detect key fat-filled particles in the brain

Scientists have created a method to detect key fat-filled particles known as lipoproteins in the central nervous system, opening a new view into the workings of the brain.

12 Sep 2023

Is exposure to infections or autoimmune diseases associated with dementia incidence?

The relationships between hospital-identified infections, autoimmune diseases, and the onset of dementia.

12 Sep 2023

Study evaluating intranasal anti-CD3 for treatment of Alzheimer’s disease published in the PNAS journal

Tiziana Life Sciences Ltd. (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies via novel routes of drug delivery, today announced acceptance of a publication, “Nasal Administration of anti-CD3 monoclonal antibody (mAb) ameliorates disease in a mouse model of Alzheimer’s disease”, in the preeminent journal, Proceedings of the National Academy of Sciences (PNAS), that supports foralumab’s mechanism as a potential treatment for Alzheimer’s disease (AD), a difficult-to-treat neuroinflammatory disease.

9 Sep 2023

Irisin-based therapies may help combat Alzheimer’s disease

Researchers who previously developed the first 3D human cell culture models of Alzheimer's disease (AD) that displays two major hallmarks of the condition-;the generation of amyloid beta deposits followed by tau tangles-;have now used their model to investigate whether the exercise-induced muscle hormone irisin affects amyloid beta pathology.

8 Sep 2023

FAU researchers discover novel method to identify therapeutic agents to treat addiction

According to the Substance Abuse and Mental Health Services Administration, approximately 40 million people in the United States had a substance use disorder in 2020.

8 Sep 2023

The role of exercise-induced hormone irisin in amyloid beta reduction

Researchers explored the biological mechanisms by which exercise-induced irisin attenuates amyloid-beta pathology in Alzheimer’s disease.

8 Sep 2023

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Researchers conducted the phase 1 trial of orally-administered senolytic therapy comprising quercetin (Q) and dasatinib (D) for symptomatic and early-stage Alzheimer's disease (AD) patients.

8 Sep 2023

Eye-tracking technology can help improve quality of life assessment for older people with dementia

More than 50% of Australians living in residential aged care facilities have a dementia diagnosis, with aged care services around the world preparing for the number of older people aged 65 years and above to double in the next 30 years.

8 Sep 2023

Breakthrough genome-wide study uncovers new loci impacting apolipoprotein E levels and Alzheimer's risk

New genetic factors that affect the plasma apolipoprotein E levels.

8 Sep 2023

Phase I trial of senolytic therapy shows promise in Alzheimer's disease

Alzheimer's disease is the most common cause of dementia that affects more than 6.5 million Americans, according to the Alzheimer's Association.

8 Sep 2023

A subset of CD8+ T cells can play a protective role against Alzheimer’s disease pathogenesis

Scientists at St. Jude Children’s Research Hospital found that a subset of CD8+ T cells in the brain lessens the activation of microglia and limits disease pathology in a model of Alzheimer’s disease.

8 Sep 2023

Antipsychotics are likely overprescribed among homebound patients with dementia, study shows

New research published in the Journal of the American Geriatrics Society indicates that antipsychotics are likely overprescribed and used inappropriately among patients with Alzheimer's disease and related dementias (ADRD) receiving home health care, and such use is linked to worse patient outcomes.

7 Sep 2023

New study to determine if intermittent fasting or weight loss can slow aging

Studies have shown that intermittent fasting can help people lose weight and may be easier to follow than counting calories to lose weight, such as traditional calorie restriction.

7 Sep 2023

People with traumatic brain injuries in earlier life may be at increased risk of late life cognitive decline

A study of twins shows that having a concussion early in life is tied to having lower scores on tests of thinking and memory skills decades later as well as having more rapid decline in those scores than twins who did not have a concussion, or traumatic brain injury (TBI).

7 Sep 2023

IU study sheds new light on the genetic underpinnings of Alzheimer's disease

A groundbreaking study led by experts from Indiana University School of Medicine has shed new light on the genetic underpinnings of Alzheimer's disease.

6 Sep 2023

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

To reimagine existing preclinical trials for Alzheimer's disease, University of Pittsburgh School of Medicine neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmoset monkeys, outlining their approach in Alzheimer's & Dementia: Translational Research & Clinical Interventions.

6 Sep 2023

World-renowned menopause experts summarize the state of menopause knowledge and advocate for further research

In a recent review published in Cell, a group of authors delved into the complexities of menopause, assessed its global impacts on health, and evaluated the effectiveness and safety of current treatments, emphasizing the importance of further research.

6 Sep 2023

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Shorter telomere length of leucocytes may signal heightened dementia risk

Unlocking the future of dementia: Your telomere length could predict your risk

Sedentary behavior linked to increased risk of dementia in adults over 60

Scientists develop new method to detect key fat-filled particles in the brain

Is exposure to infections or autoimmune diseases associated with dementia incidence?

Study evaluating intranasal anti-CD3 for treatment of Alzheimer’s disease published in the PNAS journal

Irisin-based therapies may help combat Alzheimer’s disease

FAU researchers discover novel method to identify therapeutic agents to treat addiction

The role of exercise-induced hormone irisin in amyloid beta reduction

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Eye-tracking technology can help improve quality of life assessment for older people with dementia

Breakthrough genome-wide study uncovers new loci impacting apolipoprotein E levels and Alzheimer's risk

Phase I trial of senolytic therapy shows promise in Alzheimer's disease

A subset of CD8+ T cells can play a protective role against Alzheimer’s disease pathogenesis

Antipsychotics are likely overprescribed among homebound patients with dementia, study shows

New study to determine if intermittent fasting or weight loss can slow aging

People with traumatic brain injuries in earlier life may be at increased risk of late life cognitive decline

IU study sheds new light on the genetic underpinnings of Alzheimer's disease

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

World-renowned menopause experts summarize the state of menopause knowledge and advocate for further research

eBook: Neurodegeneration Therapeutics Discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Neurodegeneration Therapeutics Discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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