Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

New study suggests protective effect of alcohol consumption on risk of AD in female nonsmokers

Knowledge regarding environmental factors influencing the risk of Alzheimer's disease is surprisingly scarce, despite substantial research in this area. In particular, the roles of smoking and alcohol consumption still remain controversial. A new study published this month in the Journal of Alzheimer's Disease suggests a protective effect of alcohol consumption on the risk of Alzheimer's disease, particularly in women who do not smoke.

24 May 2010

Researchers look for new ways of targeting Alzheimer's disease

The Alzheimer's Association released a report on Wednesday, May 19, predicting that the cost of Alzheimer's disease over the next 40 years would reach $20 trillion if newer treatments are not on the horizon.

24 May 2010

Lithium reduces brain inflammation by adjusting metabolism of DHA: Researchers

Though it has been prescribed for over 50 years to treat bipolar disorder, there are still many questions regarding exactly how lithium works. However, in a study appearing in this month's Journal of Lipid Research, researchers have provided solid evidence that lithium reduces brain inflammation by adjusting the metabolism of the health-protective omega-3-fatty acid called DHA.

24 May 2010

SiMoA technology measures individual PSA molecules in prostate cancer patients: Nature Biotechnology

Quanterix Corporation, the single molecule diagnostics company focused on developing and commercializing high sensitivity tests, announced the publication of a breakthrough study of the company's proprietary technology that demonstrates an unprecedented sensitivity for measuring a biomarker for prostate cancer recurrence.

24 May 2010

Stem cell research could lead to new treatment strategies for motor neuron disease

The Motor Neurone Disease Association is funding its first ever stem cell research programme to help unlock the secrets of this fatal, neurological condition.

24 May 2010

European researchers define research priorities in biogerontology

The quality of the medical care for geriatric patients is a major investment for society and must imperatively be a research priority in Europe. This is why 50 European researchers, met on May 17 - 19 in Brussels, to define the research priorities in the field of biogerontology for the next 10 to 15 years.

21 May 2010

UF awarded $1.2M grant to support UF-HHMI Science for Life Program

Imagine a chemistry professor and a neuroscientist working together to test a new drug to fight Alzheimer's disease, or a biomedical engineer working with an orthopedic surgeon to help patients walk again.

21 May 2010

German states may face healthcare crisis: Study

Within the next ten years, there will be deficiencies in healthcare provision in parts of Mecklenburg-West Pomerania. This is the conclusion reached by Ulrike Siewert of Greifswald University and her coauthors in the current edition of Deutsches -rzteblatt International.

21 May 2010

Prescribing practices for dementia patients

Demented patients are often treated nonspecifically with psychoactive medications. Neuroleptic drugs are given even when they are not specifically indicated, as Tomislav Majic and his colleagues from the Charit- Hospital, Berlin, show in the current issue of Deutsches -rzteblatt International.

21 May 2010

Dementia patients treated with neuroleptic drugs instead of anti-dementia medication: Study

Demented patients are often treated nonspecifically with psychoactive medications. Neuroleptic drugs are given even when they are not specifically indicated, as Tomislav Majic and his colleagues from the Charité Hospital, Berlin, show in the current issue of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2010; 107[18]: 320-7).

21 May 2010

COTI reports positive results from first phase of HIV integrase inhibitor discovery program

Critical Outcome Technologies Inc. today announced positive results from the first phase of its HIV integrase inhibitor discovery program. These results provide novel intellectual property to the Company and further validation of the CHEMSAS® drug discovery technology.

21 May 2010

Basque researchers find new Alzheimer's-related mechanism

Researchers from the University of the Basque Country have found a new Alzheimer's-related mechanism that could give rise to the development of new therapies against this disease. The study was recently published in the Cell Calcium journal, and the authors have already applied for a European patent to protect the commercial exploitation of this new discovery.

20 May 2010

Study confirms inverse association of increase in BMI with lower brain volumes

Researchers from Boston University School of Medicine determined that excess abdominal fat places otherwise healthy, middle-aged people at risk for dementia later in life. Preliminary findings suggest a relationship between obesity and dementia that could lead to promising prevention strategies in the future. Results of this study are published early online in Annals of Neurology, a journal of the American Neurological Association.

20 May 2010

275% rise in dementia cases for Australia over next 40 years: Study

According to an Access Economics study commissioned by the Alzheimer’s Australia the number of Victorian dementia patients will quadruple in the next 40 years. At present the figures stand at 66,000 and are expected to touch 246,000 in 2050. The rise is an alarming 275% and is fueled by population growth, reduced physical activity, and an increasingly ageing population. Alzheimer’s Australia warns Victorian Health authorities to start planning for measures to curb the epidemic.

19 May 2010

Targacept commences Phase 2 clinical proof of concept trial of TC-5619 in adults with ADHD

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics (TM), today announced that it has initiated a Phase 2 clinical proof of concept trial of TC-5619 in adults with attention deficit/hyperactivity disorder (ADHD). TC-5619 is a novel small molecule that is highly selective for the alpha7 neuronal nicotinic receptor, which Targacept refers to as NNR, and was discovered by Targacept scientists using Targacept's proprietary drug discovery platform known as Pentad (TM).

19 May 2010

Research team converts astroglia into two main classes of cortical neurons

The research team led by Professor Magdalena Götz of Helmholtz Zentrum München and Ludwig-Maximilians-Universität (LMU) Munich reports a major step forward in discovering a therapy for neurodegenerative diseases such as Alzheimer's or stroke. The researchers were able to convert glial cells of the brain into two different functional classes of neurons. The findings are published on May 18th in the renowned journal PLoS Biology.

19 May 2010

Study examines impact of APOE ε4 on cognitive function, brain anatomy in AD patients

In the most comprehensive study to date, neurologists have clearly identified significant differences in the ways that Alzheimer's disease affects patients with and without the apolipoprotein E ε4 gene, a known genetic risk factor for the neurodegenerative disease, using a combination of cognitive and neuroanatomic measures. The study found that this gene influences the way the disease manifests, even at its mildest clinical stages.

19 May 2010

TPP raises £9.6M to develop early-stage pre-clinical drug candidates

TPP Global Development, an innovative drug development company, announced today it has raised £9.6m which will be used to execute the Company's strategy to develop early-stage pre-clinical drug candidates.

19 May 2010

Diabetic patients with limited health literacy are at higher risk for hypoglycemia: Study

People with diabetes who have limited health literacy are at higher risk for hypoglycemia or low blood sugar, according to a new study from researchers at the University of California, San Francisco and the Kaiser Permanente Division of Research in Oakland, CA.

19 May 2010

Taking the final step from the bench to the hospital or clinic bedside

A new Regenstrief Institute and Indiana University Center for Aging Research (IUCAR) study provides effective strategies to help hospital systems, physicians and other care providers to overcome end zone hurdles and actually take evidence-based research to the patient’s hospital or clinic bedside.

18 May 2010

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

New study suggests protective effect of alcohol consumption on risk of AD in female nonsmokers

Researchers look for new ways of targeting Alzheimer's disease

Lithium reduces brain inflammation by adjusting metabolism of DHA: Researchers

SiMoA technology measures individual PSA molecules in prostate cancer patients: Nature Biotechnology

Stem cell research could lead to new treatment strategies for motor neuron disease

European researchers define research priorities in biogerontology

UF awarded $1.2M grant to support UF-HHMI Science for Life Program

German states may face healthcare crisis: Study

Prescribing practices for dementia patients

Dementia patients treated with neuroleptic drugs instead of anti-dementia medication: Study

COTI reports positive results from first phase of HIV integrase inhibitor discovery program

Basque researchers find new Alzheimer's-related mechanism

Study confirms inverse association of increase in BMI with lower brain volumes

275% rise in dementia cases for Australia over next 40 years: Study

Targacept commences Phase 2 clinical proof of concept trial of TC-5619 in adults with ADHD

Research team converts astroglia into two main classes of cortical neurons

Study examines impact of APOE ε4 on cognitive function, brain anatomy in AD patients

TPP raises £9.6M to develop early-stage pre-clinical drug candidates

Diabetic patients with limited health literacy are at higher risk for hypoglycemia: Study

Taking the final step from the bench to the hospital or clinic bedside

eBook: Neurodegeneration Therapeutics Discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Neurodegeneration Therapeutics Discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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