Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Researchers have successfully combined computer modeling and experimental results in folding studies for small proteins

In unprecedented new research, scientists at Rice University have combined theory and experiment for the first time to both predict theoretically and verify experimentally the protein-folding dynamics of a large, complex protein.

3 Oct 2005

Potential beneficial effect of copper orotate

As one of the services for patients with Alzheimer's disease, the Department of Psychiatry at the Saarland University Medical Center offers participation in a clinical phase II trial. This clinical trial aims to elucidate a potential beneficial effect of copper orotate (an organic copper salt), which is given together with a standard cholinesterase inhibitor.

3 Oct 2005

Determining levels of homocysteine may be one way to intervene in mild cognitive deficit early in the adult life-cycle

...according to a recent study by a research team led by Merrill F. Elias, a professor of epidemiology in the Statistics and Consulting Unit of the Department of Mathematics and Statistics at Boston University.

28 Sep 2005

Loss of body mass over time appears to be strongly linked to older adults' risk of developing Alzheimer's disease

The findings are the first to associate decline in body mass index (BMI) with the eventual onset of AD. The researchers suggest that the loss of body mass reflects disease processes and that change in BMI might be a clinical predictor of the development of AD.

26 Sep 2005

Tests of cognitive function are the best way so far to predict whether healthy elderly people will develop Alzheimer's

Although Alzheimer's disease begins long before symptoms appear, early diagnosis of Alzheimer's has so far been elusive. And given that there is no cure for the disease, benefits of early detection remain questionable.

26 Sep 2005

Scientists reverse memory loss in mice with Alzheimer's

In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease.

26 Sep 2005

Possible molecular origin of at least nine human diseases of nervous system degeneration

These neurodegenerative diseases, including Huntington's disease, share an abnormal deposit of proteins inside nerve cells. This deposition of protein results from a kind of genetic stutter within the cell's nucleus asking for multiple copies of the amino acid glutamine, a building block of protein structure.

26 Sep 2005

Notch1 and Jagged1 genes are likely markers indicating a patient's probable aggressive breast cancer

In a new study, scientists at The Hospital for Sick Children and Princess Margaret Hospital have shown that two genes called Notch1 and Jagged1 are linked to more aggressive breast cancers and that patients are less likely to survive the disease when these two genes are highly expressed.

26 Sep 2005

Two recent studies may help clinicians and researchers better predict and understand dementia of the Alzheimer's type

Both studies appear in the September issue of Neuropsychology, which is published by the American Psychological Association (APA). Psychologists focus on early detection in part because current medications are useful only when given very early in the course of the disease.

26 Sep 2005

HIV-infected macrophages in the brain continuously travel to part of the brain Alzheimer's disease often damages

Bacteria-eating cells that generally fight infection may cause dementia in HIV patients, University of Florida and University of California at San Francisco researchers have found.

26 Sep 2005

Prediction of new polymorph of the Alzheimer's drug, piracetam

A challenge, presented at last year's e-Science All Hands meeting, has resulted in an e-Science project achieving one of the holy grails of the pharmaceutical industry - the computational prediction of a previously unidentified crystal structure, or polymorph, of a drug molecule.

22 Sep 2005

Botox helps explain possible causes of nerve diseases

Botox, used by Hollywood stars to smooth out facial wrinkles, is playing an important role in UQ research to understand how nerve cells communicate with each other.

22 Sep 2005

First clinical guidelines to help improve the diagnosis and treatment of people with normal pressure hydrocephalus

An international team of medical experts led by a Virginia Commonwealth University researcher has established the first clinical guidelines to help improve the diagnosis and treatment of people with normal pressure hydrocephalus, a debilitating condition in the brain that often goes undiagnosed or is misdiagnosed as Alzheimer's or Parkinson's disease.

21 Sep 2005

Failure to block out inappropriate sensory stimulation activity in Alzheimer disease

Some people close their eyes when they listen to music, others wear earplugs when they read in noisy places. Both serve to block out inappropriate sensory stimulation, something that happens automatically when we concentrate.

21 Sep 2005

Green tea may protect the brain against Alzheimer's disease

Researchers at the University of South Florida (USF) have found that green tea may offer another potential health benefit - protecting the brain against the ravages of Alzheimer's disease.

20 Sep 2005

Prions rapidly 'remodel' good protein into bad

Two Brown Medical School biologists have figured out the fate of healthy protein when it comes in contact with the infectious prion form in yeast: The protein converts to the prion form, rendering it infectious. In an instant, good protein goes bad.

19 Sep 2005

Can we reverse mental declines? Well, for most of us, the answer is yes

As we get beyond retirement age, most of us will not be as mentally sharp as we once were. But a researcher at the University of Alberta says most people have the ability to reverse the mental declines that come with aging.

19 Sep 2005

Clioquinol appears to block the genetic action of Huntington's disease

Clioquinol, an antibiotic that was banned for internal use in the United States in 1971 but is still used in topical applications, appears to block the genetic action of Huntington's disease in mice and in cell culture, according to a study reported by San Francisco VA Medical Center (SFVAMC) researchers.

12 Sep 2005

Scientists characterize the most infectious prion protein particles

A new study of prions - apparently malformed proteins that initiate deadly brain diseases such as Creutzfeldt-Jakob disease in humans - has yielded surprising information about how the size of prions relates to their infectivity.

10 Sep 2005

Call for more donations of brains to help researchers discover new treatments for neurological disorders

Speaking at the BA Festival of Science, at Trinity College, Dublin, Dr Kirstin Goldring from Imperial College London and Charing Cross Hospital is calling for more donations of brains to help researchers discover new treatments for neurological disorders.

7 Sep 2005

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Researchers have successfully combined computer modeling and experimental results in folding studies for small proteins

Potential beneficial effect of copper orotate

Determining levels of homocysteine may be one way to intervene in mild cognitive deficit early in the adult life-cycle

Loss of body mass over time appears to be strongly linked to older adults' risk of developing Alzheimer's disease

Tests of cognitive function are the best way so far to predict whether healthy elderly people will develop Alzheimer's

Scientists reverse memory loss in mice with Alzheimer's

Possible molecular origin of at least nine human diseases of nervous system degeneration

Notch1 and Jagged1 genes are likely markers indicating a patient's probable aggressive breast cancer

Two recent studies may help clinicians and researchers better predict and understand dementia of the Alzheimer's type

HIV-infected macrophages in the brain continuously travel to part of the brain Alzheimer's disease often damages

Prediction of new polymorph of the Alzheimer's drug, piracetam

Botox helps explain possible causes of nerve diseases

First clinical guidelines to help improve the diagnosis and treatment of people with normal pressure hydrocephalus

Failure to block out inappropriate sensory stimulation activity in Alzheimer disease

Green tea may protect the brain against Alzheimer's disease

Prions rapidly 'remodel' good protein into bad

Can we reverse mental declines? Well, for most of us, the answer is yes

Clioquinol appears to block the genetic action of Huntington's disease

Scientists characterize the most infectious prion protein particles

Call for more donations of brains to help researchers discover new treatments for neurological disorders

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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