Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Irisin-based therapies may help combat Alzheimer’s disease

Researchers who previously developed the first 3D human cell culture models of Alzheimer's disease (AD) that displays two major hallmarks of the condition - the generation of amyloid beta deposits followed by tau tangles - have now used their model to investigate whether the exercise-induced muscle hormone irisin affects amyloid beta pathology.

8 Sep 2023

FAU researchers discover novel method to identify therapeutic agents to treat addiction

According to the Substance Abuse and Mental Health Services Administration, approximately 40 million people in the United States had a substance use disorder in 2020.

8 Sep 2023

The role of exercise-induced hormone irisin in amyloid beta reduction

Researchers explored the biological mechanisms by which exercise-induced irisin attenuates amyloid-beta pathology in Alzheimer’s disease.

8 Sep 2023

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Researchers conducted the phase 1 trial of orally-administered senolytic therapy comprising quercetin (Q) and dasatinib (D) for symptomatic and early-stage Alzheimer's disease (AD) patients.

8 Sep 2023

Eye-tracking technology can help improve quality of life assessment for older people with dementia

More than 50% of Australians living in residential aged care facilities have a dementia diagnosis, with aged care services around the world preparing for the number of older people aged 65 years and above to double in the next 30 years.

8 Sep 2023

Breakthrough genome-wide study uncovers new loci impacting apolipoprotein E levels and Alzheimer's risk

New genetic factors that affect the plasma apolipoprotein E levels.

8 Sep 2023

Phase I trial of senolytic therapy shows promise in Alzheimer's disease

Alzheimer's disease is the most common cause of dementia that affects more than 6.5 million Americans, according to the Alzheimer's Association.

8 Sep 2023

A subset of CD8+ T cells can play a protective role against Alzheimer’s disease pathogenesis

Scientists at St. Jude Children’s Research Hospital found that a subset of CD8+ T cells in the brain lessens the activation of microglia and limits disease pathology in a model of Alzheimer’s disease.

8 Sep 2023

Antipsychotics are likely overprescribed among homebound patients with dementia, study shows

New research published in the Journal of the American Geriatrics Society indicates that antipsychotics are likely overprescribed and used inappropriately among patients with Alzheimer's disease and related dementias (ADRD) receiving home health care, and such use is linked to worse patient outcomes.

7 Sep 2023

New study to determine if intermittent fasting or weight loss can slow aging

Studies have shown that intermittent fasting can help people lose weight and may be easier to follow than counting calories to lose weight, such as traditional calorie restriction.

7 Sep 2023

People with traumatic brain injuries in earlier life may be at increased risk of late life cognitive decline

A study of twins shows that having a concussion early in life is tied to having lower scores on tests of thinking and memory skills decades later as well as having more rapid decline in those scores than twins who did not have a concussion, or traumatic brain injury (TBI).

7 Sep 2023

IU study sheds new light on the genetic underpinnings of Alzheimer's disease

A groundbreaking study led by experts from Indiana University School of Medicine has shed new light on the genetic underpinnings of Alzheimer's disease.

6 Sep 2023

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

To reimagine existing preclinical trials for Alzheimer's disease, University of Pittsburgh School of Medicine neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmoset monkeys, outlining their approach in Alzheimer's & Dementia: Translational Research & Clinical Interventions.

6 Sep 2023

World-renowned menopause experts summarize the state of menopause knowledge and advocate for further research

In a recent review published in Cell, a group of authors delved into the complexities of menopause, assessed its global impacts on health, and evaluated the effectiveness and safety of current treatments, emphasizing the importance of further research.

6 Sep 2023

Could medicinal plants be the key to reversing cognitive decline?

Researchers explore available evidence that medicinal plants may help improve cognitive function by reducing brain inflammation.

5 Sep 2023

OHSU scientists discover new avenue of cell death in Alzheimer's disease and vascular dementia

Researchers have discovered a new avenue of cell death in Alzheimer's disease and vascular dementia.

5 Sep 2023

DOAC use associated with reduction in dementia risk compared to traditional blood thinners

The use of direct oral anticoagulants (DOACs) was associated with a reduction in dementia risk compared to traditional blood thinners - like warfarin - in atrial fibrillation patients, particularly in Asian patients.

5 Sep 2023

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Researchers have developed a new blood test that measures mitochondrial DNA damage as a potential marker for Parkinson's disease (PD). The study shows the test could aid in diagnosing PD and assessing responses to LRRK2 kinase inhibitors, which may help in reducing mitochondrial damage in PD patients.

4 Sep 2023

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Researchers investigated the impact of biological sex on protein levels and its genomic control by analyzing 1,277 proteomes of the brain.

4 Sep 2023

New biomarker could help identify people at risk for vascular dementia

Dementia is a group of brain diseases that share similar symptoms, such as memory, language, orientation, and behavioral issues. Vascular dementia generally develops in the elderly, affecting between 1% and 4% of people over the age of 65, according to Alzheimer's Switzerland.

4 Sep 2023

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Irisin-based therapies may help combat Alzheimer’s disease

FAU researchers discover novel method to identify therapeutic agents to treat addiction

The role of exercise-induced hormone irisin in amyloid beta reduction

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Eye-tracking technology can help improve quality of life assessment for older people with dementia

Breakthrough genome-wide study uncovers new loci impacting apolipoprotein E levels and Alzheimer's risk

Phase I trial of senolytic therapy shows promise in Alzheimer's disease

A subset of CD8+ T cells can play a protective role against Alzheimer’s disease pathogenesis

Antipsychotics are likely overprescribed among homebound patients with dementia, study shows

New study to determine if intermittent fasting or weight loss can slow aging

People with traumatic brain injuries in earlier life may be at increased risk of late life cognitive decline

IU study sheds new light on the genetic underpinnings of Alzheimer's disease

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

World-renowned menopause experts summarize the state of menopause knowledge and advocate for further research

Could medicinal plants be the key to reversing cognitive decline?

OHSU scientists discover new avenue of cell death in Alzheimer's disease and vascular dementia

DOAC use associated with reduction in dementia risk compared to traditional blood thinners

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

New biomarker could help identify people at risk for vascular dementia

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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