Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

If you've ever wondered how a vaccine given decades ago can still protect against infection, you have your plasma cells to thank. Plasma cells are long-lived B cells that reside in the bone marrow and churn out antibodies against previously encountered vaccines or pathogens.

22 Feb 2017

HMS scientists listen to crosstalk between gut microbes and immune system

The human gut is home to some 100 trillion bacteria, comprising between 250 and 500 species. This astounding array of organisms, collectively known as the gut microbiome, is a powerful regulator of disease and health and has been implicated in conditions ranging from inflammatory bowel disease to multiple sclerosis.

16 Feb 2017

Clinical trial to test potential new drug treatment for osteoarthritis

The University of Liverpool, in partnership with AKL Research and Development Ltd, is to lead on a clinical trial to test a potential new drug treatment for osteoarthritis.

16 Feb 2017

Experts establish first set of diagnostic criteria for life-threatening idiopathic multicentric CD

More than six decades after Castleman disease was first described, a group of experts from Penn Medicine and other institutions around the world has established the first set of diagnostic criteria for a life-threatening subtype of the condition, idiopathic multicentric CD, which is often misdiagnosed as other illnesses.

16 Feb 2017

TSRI scientists describe how key molecules in the brain work together to trigger intense anxiety

In a new study, researchers at The Scripps Research Institute have described how two important molecules in the brain work together to trigger intense anxiety.

13 Feb 2017

Researchers identify E. coli bacteria linking Crohn's disease to spondyloarthritis

Patients with Crohn's disease, a type of inflammatory bowel disease (IBD) that causes abdominal pain and diarrhea, can also experience joint pain.

9 Feb 2017

Genetic variant encoded in NCF1 linked to increased risk for autoimmune diseases, study shows

Investigators at the Medical University of South Carolina report pre-clinical research showing that a genetic variant encoded in neutrophil cystolic factor 1 (NCF1) is associated with increased risk for autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and Sjögren's syndrome, in the January 2017 issue of Nature Genetics.

8 Feb 2017

Scientists identify beliefs that may influence South Asian patients from taking diabetes medication

The social stigma associated with diabetes and a fear of being poisoned by medical drugs may contribute to patients of South Asian origin failing to take their medication, a new study shows.

8 Feb 2017

Quadricep strength, speed of force production linked to physical function in knee OA patients

Quadricep strength and speed of force production both affect physical functioning in people with, or at risk for, knee osteoarthritis, according to research presented this week at the Association of Academic Physiatrists Annual Meeting in Las Vegas.

7 Feb 2017

New article outlines identical symptoms linked to hip and spine pain

Many patients live with low back pain that radiates to the buttock, groin, thigh, and even knees. The challenge for patients, and often their doctors, is determining the origin of the pain -- the hip, the spine, or both.

7 Feb 2017

Common drug for autoimmune disease may increase risk of myeloid neoplasms

Mayo Clinic researchers have found that azathioprine, a drug commonly used to treat autoimmune disease, may increase the risk of myeloid neoplasms.

3 Feb 2017

TSRI chemists create new technique for constructing chiral drug molecules

Chemists at The Scripps Research Institute (TSRI) have invented a new technique for constructing chiral drug molecules.

3 Feb 2017

UW-Madison scientists discover bone marrow proteins that regulate bone-building cells

The prospect of regenerating bone lost to cancer or trauma is a step closer to the clinic as University of Wisconsin-Madison scientists have identified two proteins found in bone marrow as key regulators of the master cells responsible for making new bone.

2 Feb 2017

Conventional therapies do not sufficiently treat psoriasis patients, study suggests

A substantial part of people, one in five, undergoing systemic treatment for psoriasis till have considerable problems with their disease.

2 Feb 2017

Deep brain stimulation can reduce heroin relapse in rat models of addiction, TSRI study shows

Scientists at The Scripps Research Institute have found that deep brain stimulation (DBS) can greatly reduce the compulsion to use heroin in standard rat models of addiction.

2 Feb 2017

Cardiologist reveals 13 facts about heart disease in women

Every minute, a woman dies from heart disease in the United States - it is the number one killer of women, causing one in three deaths each year, according to the American Heart Association.

1 Feb 2017

Johns Hopkins researchers uncover mechanism in chikungunya virus that controls disease severity

Researchers led by the Johns Hopkins Bloomberg School of Public Health have identified a mechanism by which the chikungunya virus infects healthy cells and controls how severe the disease it causes will be, a mechanism they believe can be found in a number of other related viruses for which there are no treatments or licensed vaccines.

31 Jan 2017

TSRI study offers first look at early stages of brain development in patients with Fragile X syndrome

A new study led by scientists at The Scripps Research Institute is giving researchers a first look at the early stages of brain development in patients with Fragile X syndrome, a disorder that causes mild to severe intellectual disability and is the most common genetic cause of autism spectrum disorder.

31 Jan 2017

Misdiagnosis of common foot and ankle injuries may lead to long-term disability, pain and arthritis

Front-line physicians are advised to err on the side of caution and opt for additional imaging and second opinions when diagnosing six common foot and ankle injuries.

30 Jan 2017

PillTime: New free prescription service makes life easy for patients and carers

In the UK alone, there are 14.6 million patients who are on repeat medication. Of those, some 11.6 million are over 65 years old and will be prescribed more than five ‘regular’ items on their prescription.

27 Jan 2017

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

HMS scientists listen to crosstalk between gut microbes and immune system

Clinical trial to test potential new drug treatment for osteoarthritis

Experts establish first set of diagnostic criteria for life-threatening idiopathic multicentric CD

TSRI scientists describe how key molecules in the brain work together to trigger intense anxiety

Researchers identify E. coli bacteria linking Crohn's disease to spondyloarthritis

Genetic variant encoded in NCF1 linked to increased risk for autoimmune diseases, study shows

Scientists identify beliefs that may influence South Asian patients from taking diabetes medication

Quadricep strength, speed of force production linked to physical function in knee OA patients

New article outlines identical symptoms linked to hip and spine pain

Common drug for autoimmune disease may increase risk of myeloid neoplasms

TSRI chemists create new technique for constructing chiral drug molecules

UW-Madison scientists discover bone marrow proteins that regulate bone-building cells

Conventional therapies do not sufficiently treat psoriasis patients, study suggests

Deep brain stimulation can reduce heroin relapse in rat models of addiction, TSRI study shows

Cardiologist reveals 13 facts about heart disease in women

Johns Hopkins researchers uncover mechanism in chikungunya virus that controls disease severity

TSRI study offers first look at early stages of brain development in patients with Fragile X syndrome

Misdiagnosis of common foot and ankle injuries may lead to long-term disability, pain and arthritis

PillTime: New free prescription service makes life easy for patients and carers

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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