Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Mutant protein responsible for cystic fibrosis talks to wrong cellular neighbors

Scientists at The Scripps Research Institute have found evidence that a mutant protein responsible for most cases of cystic fibrosis is so busy "talking" to the wrong cellular neighbors that it cannot function normally and is prematurely degraded.

1 Dec 2015

Research sheds light on genetic factors involved in autoimmune diseases

A collaboration between researchers at the Babraham Institute and the University of Manchester has mapped the physical connections occurring in the genome to shed light on the parts of the genome involved in autoimmune diseases. Using a new technique, called Capture Hi-C, the team revealed novel insights into how changes in the genetic sequence have a biological effect and increase the risk of disease.

30 Nov 2015

New research reveals how gaps between gene interactions influence disease risk

New research from The University of Manchester and the Brabraham Institute has revealed how gaps between genes interact to influence the risk of acquiring diseases such as arthritis and type 1 diabetes.

30 Nov 2015

Mallinckrodt sells CMDS business to Guerbet for $270 million

Mallinckrodt plc, a leading specialty biopharmaceutical company, announced today that it has closed the sale of its global contrast media and delivery systems (CMDS) business to Guerbet in a transaction valued at approximately $270 million.

28 Nov 2015

Can-Fite BioPharma reports financial results, provides updates on drug development programs

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs being developed to treat inflammatory diseases, cancer and sexual dysfunction, today reported financial results for the nine months ended September 30, 2015 and updates on its drug development programs.

27 Nov 2015

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a study in The Journal of Infectious Diseases.

25 Nov 2015

Researchers offer novel solution to promote successful radiotherapy for cancer patients

Researchers at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai have discovered a key mechanism by which radiation treatment (radiotherapy) fails to completely destroy tumors. And, in the journal Nature Immunology, they offer a novel solution to promote successful radiotherapy for the millions of cancer patients who are treated with it.

25 Nov 2015

Novartis announces EC approval of Cosentyx for treatment of ankylosing spondylitis, psoriatic arthritis

Novartis announced today that the European Commission has approved Cosentyx (secukinumab) for the treatment of people living with ankylosing spondylitis (AS) and psoriatic arthritis (PsA). For AS, this is the first new treatment advance in 16 years since the development of the current standard of care, anti-tumor necrosis factor (anti-TNF) therapy.

25 Nov 2015

High-fat diet appears to prompt immune cells to start consuming connections between neurons

When a high-fat diet causes us to become obese, it also appears to prompt normally bustling immune cells in our brain to become sedentary and start consuming the connections between our neurons, scientists say.

24 Nov 2015

Health experts urge lawmakers, regulators to close loopholes in Orphan Drug Act

Health experts at Johns Hopkins Medicine are calling on lawmakers and regulators to close loopholes in the Orphan Drug Act they claim give drug companies millions of dollars in unintended and misplaced subsidies and tax breaks and fuel skyrocketing medication costs.

20 Nov 2015

TSRI researchers awarded $1.6 million grant to advance preclinical studies of potential heroin vaccine

Now researchers at The Scripps Research Institute have been awarded a prestigious Translational Avant-Garde Award, which supports the development of medications for substance abuse disorders, from the National Institutes of Health National Institute on Drug Abuse.

20 Nov 2015

Researchers devise system to accelerate the process of making life-saving vaccines

Researchers at Brigham Young University have devised a system to speed up the process of making life-saving vaccines for new viruses.

20 Nov 2015

Lilly, Merck expand oncology clinical trial collaboration

Eli Lilly and Company and Merck, known as MSD outside the United States and Canada, today announced the extension of an existing collaboration to evaluate the safety and efficacy of the combination of Lilly's ALIMTA (pemetrexed for injection) and Merck's KEYTRUDA (pembrolizumab) in a pivotal Phase III study in first-line nonsquamous non-small cell lung cancer (NSCLC).

19 Nov 2015

Matthew Teeter recognized with 2015 John Charles Polanyi Prize for research in joint replacement

Matthew Teeter, PhD, an assistant professor at Western University's Schulich School of Medicine & Dentistry and researcher at Lawson Health Research Institute, is a winner of the 2015 John Charles Polanyi Prize. The $20,000 award recognizes the excellence of Teeter's research in joint replacement.

18 Nov 2015

TSRI scientists discover first-in-class compounds that target persistent tuberculosis

Tuberculosis has been infecting humans for several millennia, making it one of the most horribly successful diseases in history. Today, it is still a major killer, responsible for some 1.5 million deaths each year.

18 Nov 2015

Coating implants with certain 'activator' can prevent S. aureus infection

Biofilms frequently coat the surfaces of catheters, and of various medical implants and prostheses, where they can cause life-threatening infections. New research at the Sahlgrenska Academy show that coating implants with a certain "activator" can prevent Staphylococcus aureus, the leading cause of hospital-acquired infections, from forming biofilms.

18 Nov 2015

$HSS researchers study outcomes of novel implant in patients undergoing wrist fracture surgery$

HSS researchers study outcomes of novel implant in patients undergoing wrist fracture surgery

Researchers at Hospital for Special Surgery have launched a study to determine if a novel implant allowing for less invasive surgery for a broken wrist leads to a quicker recovery, less post-operative pain and fewer complications compared to conventional surgical treatment.

17 Nov 2015

Vanderbilt study could lead to development of new drugs that relieve pain without causing vascular effects

It's been about a decade since the promise of COX-2 inhibitors -- drugs that relieve arthritis pain and inflammation without the gastrointestinal side effects of other painkillers -- was tempered by the realization that they could cause heart problems in some patients.

13 Nov 2015

Different types of asthma respond differently to new experimental treatment

University of Queensland research into the effects of dust mite and cockroach allergens has found that different types of asthma respond differently to a new experimental treatment.

12 Nov 2015

MedTechSouthEast competition displays advanced medical technologies for Parkinson’s patients

Laser-emitting shoes and a Meccano-style walking aid kit are just two of the inventions being developed by companies in London and the south east that could help people stay independent for longer as they get older or develop debilitating illnesses, according to Design Council and MedCity, the Mayor of London’s life sciences promotional organisation.

12 Nov 2015

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Mutant protein responsible for cystic fibrosis talks to wrong cellular neighbors

Research sheds light on genetic factors involved in autoimmune diseases

New research reveals how gaps between gene interactions influence disease risk

Mallinckrodt sells CMDS business to Guerbet for $270 million

Can-Fite BioPharma reports financial results, provides updates on drug development programs

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

Researchers offer novel solution to promote successful radiotherapy for cancer patients

Novartis announces EC approval of Cosentyx for treatment of ankylosing spondylitis, psoriatic arthritis

High-fat diet appears to prompt immune cells to start consuming connections between neurons

Health experts urge lawmakers, regulators to close loopholes in Orphan Drug Act

TSRI researchers awarded $1.6 million grant to advance preclinical studies of potential heroin vaccine

Researchers devise system to accelerate the process of making life-saving vaccines

Lilly, Merck expand oncology clinical trial collaboration

Matthew Teeter recognized with 2015 John Charles Polanyi Prize for research in joint replacement

TSRI scientists discover first-in-class compounds that target persistent tuberculosis

Coating implants with certain 'activator' can prevent S. aureus infection

HSS researchers study outcomes of novel implant in patients undergoing wrist fracture surgery

Vanderbilt study could lead to development of new drugs that relieve pain without causing vascular effects

Different types of asthma respond differently to new experimental treatment

MedTechSouthEast competition displays advanced medical technologies for Parkinson’s patients

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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