Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Researchers identify cause of post-COVID inflammatory shock in children

MIS-C is a serious inflammatory shock that affects children. It can occur several weeks after a COVID infection and can be life-threatening.

12 Mar 2025

Earlier ACL surgery may reduce risk of knee osteoarthritis

A preclinical study by HSS investigators found that earlier anterior cruciate ligament (ACL) reconstruction led to lower immune cell activity, less inflammation and fewer joint changes associated with knee osteoarthritis compared to delayed surgery.

12 Mar 2025

Natural ingredient gluconolactone offers hope for targeted lupus therapy

Lupus is an autoimmune disease where the body’s immune system attacks its own tissues and organs, causing inflammation and damaging organs.

12 Mar 2025

Regulating cell acidity could transform autoimmune disease treatments

What if treating autoimmune diseases was as simple as regulating the acidity levels of parts of patients' cells? Genetic screening may have unlocked a path for treating the severe inflammation associated with many immune diseases by regulating one protein's role in helping another protein control cell acidity, according to new research published in Cell by a team from the Perelman School of Medicine at the University of Pennsylvania.

11 Mar 2025

Arthritis and COPD together raise mortality risk

People with chronic obstructive pulmonary disease (COPD) and arthritis have a higher risk of death than people with arthritis who do not have COPD, according to a new study.

11 Mar 2025

Childhood abuse doubles adult risk of chronic health conditions

A new study published this week in Child Maltreatment found that in comparison to those who had not been abused in childhood, adults who had experienced both childhood physical and sexual abuse had approximately double the odds of physical and mental health conditions, including angina, arthritis, asthma, COPD, heart attack, depression, and disability -- even after considering respondents' age, race, income, and health behaviors, as well as obesity.

11 Mar 2025

Combination of Epstein-Barr virus antibodies and genes linked to increased risk of MS

In multiple sclerosis (MS), antibodies to the common Epstein-Barr virus can accidentally attack a protein in the brain and spinal cord. New research shows that the combination of certain viral antibodies and genetic risk factors can be linked to a greatly increased risk of MS.

10 Mar 2025

British scientists unveil world-leading technology to speed up drug discovery

A new 3D bio-printer that produces human-like tissue holds the potential to revolutionize the discovery of new drugs for cancer, heart disease and arthritis.

10 Mar 2025

Misdiagnosis of autoimmune diseases leads to long-term patient impact

A 'chasm of misunderstanding and miscommunication' is often experienced between clinicians and patients, leading to autoimmune diseases such as lupus and vasculitis being wrongly diagnosed as psychiatric or psychosomatic conditions, with a profound and lasting impact on patients, researchers have found.

4 Mar 2025

Epstein-Barr virus infection predisposes people to develop Crohn's disease

Crohn's disease, a debilitating inflammatory bowel disease, has many known contributing factors, including bacterial changes in the microbiome that foster an inflammatory environment.

3 Mar 2025

British Heart Foundation’s Centre of Research Excellence launches at The University of Manchester

The University of Manchester has launched the British Heart Foundation (BHF) Manchester Centre of Research Excellence following an award of £4 million to support world-class cardiovascular disease from the leading charity.

From The University of Manchester 3 Mar 2025

FDA warns of dangerous products sold online with hidden active ingredients

Whether you're looking to buy weight loss, male enhancement, or certain other products, these days you're apt to look for them online, rather than at a physical store.

2 Mar 2025

Trained immunity may exacerbate inflammatory bone loss disorders

Clinical research has long focused on ways to harness the actions of the immune system. From vaccines to immunotherapies, researchers have used their knowledge of the immune system to develop therapies to treat or prevent diseases from influenza to autoimmune disease and cancer.

27 Feb 2025

Genetic mutation offers hope for better rheumatoid arthritis treatments

Research led by York University's Faculty of Health reveals how a specific mutation in a protein called TRAF1 can shut down an overactive immune response, dramatically reducing inflammation in mice.

27 Feb 2025

New gene therapy strategy could cure COPA Syndrome

Scientists compared five families and multiple generations to find a gene variant that prevents COPA Syndrome and opens the door to a new gene therapy for the condition.

27 Feb 2025

Pilot study explores potential of senolytics in Alzheimer's prevention

A new pilot study known as STAMINA (Senolytics To Alleviate Mobility Issues and Neurological Impairments in Aging), that focused on the effects of senolytic medications, Dasatinib and Quercetin (DQ), which remove old (senescent) cells from the body, suggests that intermittent treatment may hold promise for improving cognitive function in older adults at risk of Alzheimer's disease.

26 Feb 2025

Machine learning algorithm decodes immune system’s hidden data for disease detection

Your immune system harbors a lifetime's worth of information about threats it's encountered - a biological Rolodex of baddies.

24 Feb 2025

Aging isn’t just in your genes—your environment plays a bigger role, study shows

Study explores the relative contributions of genetics and environmental factors to aging and premature mortality. It highlights how the exposome—lifetime environmental exposures—shapes disease risks, with socioeconomic status, smoking, and lifestyle choices emerging as key aging determinants.

23 Feb 2025

International panel recommends avoiding spine injections for chronic pain

Spine injections should not be given to adults with chronic back pain because they provide little or no pain relief compared with sham injections, say a panel of international experts in The BMJ today.

20 Feb 2025

New study reveals LRP1's crucial role in bone formation and joint development

Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions worldwide, often causing chronic pain and disability. These disorders stem from complex genetic and environmental interactions that disrupt bone formation and joint development.

19 Feb 2025