Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

TSRI scientists identify new drugs for human prion disease

Human diseases caused by misfolded proteins known as prions are some of most rare yet terrifying on the planet—incurable with disturbing symptoms that include dementia, personality shifts, hallucinations and coordination problems.

4 Apr 2013

Same factor that helps fight off severe inflammatory ailments also functions as enemy

The same factor in our immune system that is instrumental in enabling us to fight off severe and dangerous inflammatory ailments is also a player in doing the opposite at a later stage, causing the suppression of our immune response.

4 Apr 2013

Ulcerative colitis and Crohn’s disease treatments: an interview with Dr Parikh, vice president, general medicine, Takeda

Ulcerative colitis (UC) and Crohn’s disease (CD) are both relapsing and remitting chronic diseases of bowel inflammation. By that I mean they flare and physicians try to get the flare under control and try to induce remission. However, despite a number of treatments available, they tend to relapse.

From Takeda 3 Apr 2013

Antibodies neutralize mosquito-transmitted chikungunya virus, researchers reveal

Researchers have learned the precise structure of the mosquito-transmitted chikungunya virus pathogen while it is bound to antibodies, showing how the infection is likely neutralized.

3 Apr 2013

Researchers identify link between immune response and blood clotting

Rice University researchers have found an unexpected link between a protein that triggers the formation of blood clots and other proteins that are essential for the body's immune system.

2 Apr 2013

Ampio Pharmaceuticals receives FDA IND approval to start clinical trial of Ampion

Ampio Pharmaceuticals, Inc. today announced FDA acceptance of its IND and the treatment of the first fifteen (15) patients in its clinical trial using Ampion™ to treat osteoarthritis of the knee.

2 Apr 2013

Lifestyle choices we make in adulthood influence how tall we stand as we age

Even if you didn't eat your veggies or drink your milk as a child, your height is still in your hands, reveal new findings by economists from the University of Southern California, Harvard University and Peking University.

2 Apr 2013

Ensemble Therapeutics to highlight IL-17A inhibitor Ensemblin at 245th ACS National Meeting

Ensemble Therapeutics today announced that preclinical data showing the advantages of its Ensemblins, novel macrocyclic compounds against challenging drug targets, will be presented at the 245th American Chemical Society National Meeting being held April 7-11, 2013 in New Orleans, LA.

2 Apr 2013

Research findings could lead to new targets for treating inflammatory disorders

Researchers at UC Davis have shown how the innate immune system distinguishes between dangerous pathogens and friendly microbes. Like burglars entering a house, hostile bacteria give themselves away by breaking into cells. However, sensing proteins instantly detect the invasion, triggering an alarm that mobilizes the innate immune response.

2 Apr 2013

Two nationally renowned specialists to research on Lupus, auto-immune disorders

In a new association of nationally renowned specialists on Lupus and auto-immune disorders, Dr. Swamy Venuturupalli , is joining with Dr. Daniel Wallace to accelerate research into those diseases along with their expanded clinical practice.

1 Apr 2013

Research findings could improve treatments for pneumonia, other inflammatory conditions

Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival and improved lung function in animal models of pneumonia.

1 Apr 2013

New technique for vaccine design could prove useful against HIV, other viral strains

A team led by scientists from The Scripps Research Institute (TSRI) and the International AIDS Vaccine Initiative (IAVI) has unveiled a new technique for vaccine design that could be particularly useful against HIV and other fast-changing viruses.

30 Mar 2013

Shriners Hospitals for Children -- Twin Cities become the newest member of the Mayo Clinic Care Network

Mayo Clinic today announced that Shriners Hospitals for Children -- Twin Cities (Shriners) will build on the decades-long collaboration between physicians in both organizations and become part of the Mayo Clinic Care Network.

29 Mar 2013

New way to predict woman’s final menstrual period

A new UCLA-led study suggests a way to predict when a woman will have her final menstrual period. The findings, published in the April issue of the peer-reviewed Journal of Clinical Endocrinology and Metabolism, could help women and physicians gauge the onset of menopause-related bone loss, which generally begins a year prior to the last period.

28 Mar 2013

Auxilium Pharmaceuticals reports positive results from phase IIa Frozen Shoulder Syndrome clinical trial

Auxilium Pharmaceuticals, Inc., a specialty biopharmaceutical company, today announced positive data for collagenase clostridium histolyticum or CCH which is being developed for the potential treatment, if approved by the U.S. Food and Drug Administration, of adult patients with adhesive capsulitis, commonly known as Frozen Shoulder syndrome.

26 Mar 2013

Adding lubricin to fluid in our joints may prevent osteoarthritis, researchers find

Think new discoveries are the bee's knees? This one is even better -- this research out of Rhode Island Hospital is the mice's knees. Researchers have found that adding lubricin, a protein that our bodies naturally produce, to the fluid in our joints may reduce the risk of or even prevent osteoarthritis.

25 Mar 2013

Japan's MHLW approves XELJANZ for treatment of adults with rheumatoid arthritis

Pfizer Inc. announced today that the Japanese Ministry of Health, Labor and Welfare has approved XELJANZ (tofacitinib citrate) for the treatment of adults with rheumatoid arthritis who have had an inadequate response to existing therapies.

25 Mar 2013

Study shows why certain drugs that interact with serotonin receptors have harmful effects

A team including scientists from The Scripps Research Institute (TSRI), the University of North Carolina at Chapel Hill and the Chinese Academy of Sciences has determined and analyzed the high-resolution atomic structures of two kinds of human serotonin receptor.

25 Mar 2013

Researchers study gene variants that bear signature for inflammatory disease susceptibility

In new research published in the April 4, 2013 issue of The American Journal of Human Genetics, researchers from Brigham and Women's Hospital demonstrate that some variants in our genes that could put a person at risk for inflammatory diseases such as multiple sclerosis, Crohn's disease or rheumatoid arthritis, have been the target of natural selection over the course of human history.

25 Mar 2013

Study challenges widely held belief that long nerve grafts do poorly

A study by researchers at Hospital for Special Surgery challenges a widely held belief that long nerve grafts do poorly in adults with an axillary nerve injury. Investigators found that the outcomes of long nerve grafts were comparable to those of modern nerve transfers.

25 Mar 2013

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

TSRI scientists identify new drugs for human prion disease

Same factor that helps fight off severe inflammatory ailments also functions as enemy

Ulcerative colitis and Crohn’s disease treatments: an interview with Dr Parikh, vice president, general medicine, Takeda

Antibodies neutralize mosquito-transmitted chikungunya virus, researchers reveal

Researchers identify link between immune response and blood clotting

Ampio Pharmaceuticals receives FDA IND approval to start clinical trial of Ampion

Lifestyle choices we make in adulthood influence how tall we stand as we age

Ensemble Therapeutics to highlight IL-17A inhibitor Ensemblin at 245th ACS National Meeting

Research findings could lead to new targets for treating inflammatory disorders

Two nationally renowned specialists to research on Lupus, auto-immune disorders

Research findings could improve treatments for pneumonia, other inflammatory conditions

New technique for vaccine design could prove useful against HIV, other viral strains

Shriners Hospitals for Children -- Twin Cities become the newest member of the Mayo Clinic Care Network

New way to predict woman’s final menstrual period

Auxilium Pharmaceuticals reports positive results from phase IIa Frozen Shoulder Syndrome clinical trial

Adding lubricin to fluid in our joints may prevent osteoarthritis, researchers find

Japan's MHLW approves XELJANZ for treatment of adults with rheumatoid arthritis

Study shows why certain drugs that interact with serotonin receptors have harmful effects

Researchers study gene variants that bear signature for inflammatory disease susceptibility

Study challenges widely held belief that long nerve grafts do poorly

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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