Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Obese patients more likely to have complications after total knee replacement surgery

Obese patients have a greater risk of complications following total knee replacement surgery, including post-surgical infections, according to a new literature review recently published in the Journal of Bone and Joint Surgery (JBJS).

25 Oct 2012

Lessons can be learnt from US fungal meningitis outbreak

As the current outbreak of fungal meningitis caused by contaminated methylprednisolone acetate injections continues to spread across the USA, past experience suggests that lessons can be learnt, says a US researcher.

24 Oct 2012

Interim results from CEL-SCI's Multikine Phase III study on head and neck cancer

CEL-SCI Corporation announced today that an interim review of the safety data from its open label, randomized, controlled, pivotal Phase III study of Multikine (Leukocyte Interleukin, Injection) investigational immunotherapy by an Independent Data Monitoring Committee (IDMC) raised no safety concerns.

23 Oct 2012

Computed tomography aids scleroderma lung disease prognosis

High-resolution computed tomography is useful for the prognosis of patients with systemic scleroderma-related interstitial lung disease, research shows.

22 Oct 2012

Renal denervation improves quality of life in hypertension

Renal denervation in patients with treatment-resistant hypertension results in a significantly improved quality of life, a study suggests.

22 Oct 2012

Physician shares lessons learned from fungal meningitis outbreak

In a new perspective piece being published Online First tonight in Annals of Internal Medicine, a physician recalls lessons learned from treating patients affected by the 2002 outbreak of Exophiala (Wangiella) dermatitidis meningitis or arthritis related to contaminated, injectable coticosteroids prepared from a compounding pharmacy.

20 Oct 2012

$Researchers find new way to assess risk of osteoporosis, bone fractures in women$

Researchers find new way to assess risk of osteoporosis, bone fractures in women

For women of mixed racial or ethnic backgrounds, a new method for measuring bone health may improve the odds of correctly diagnosing their risk of osteoporosis and bone fractures, according to a UCLA-led study.

20 Oct 2012

EMA CHMP issues positive opinion to Savient's KRYSTEXXA for treatment of chronic gout

Savient Pharmaceuticals, Inc. and its wholly owned subsidiary, Savient Pharma Ireland Limited, announced that the European Medicines Agency's Committee for Medicinal Products for Human Use has completed its scientific assessment and has issued a positive opinion recommending approval of a marketing authorization in the European Union for KRYSTEXXA for the treatment of severe debilitating chronic tophaceous gout in adult patients who may also have erosive joint involvement and who have failed to normalize serum uric acid with xanthine oxidase inhibitors at the maximum medically appropriate dose or for whom these medicines are contraindicated.

19 Oct 2012

Weill Cornell Medical College researcher wins 2012 William B. Coley Award

Dr. Laurie H. Glimcher, the Stephen and Suzanne Weiss Dean of Weill Cornell Medical College and provost for medical affairs of Cornell University, is a winner of the 2012 William B. Coley Award for Distinguished Research in Basic Immunology from the Cancer Research Institute for her outstanding achievements in immunology and cancer research.

19 Oct 2012

Research to determine how genes contribute to Type 1 diabetes

Diabetes is a chronic, debilitating disease which affects nearly 26 million Americans. As many as three million people have Type 1 diabetes or juvenile diabetes that usually occurs in children or young adults.

19 Oct 2012

Soccer scores hat-trick for hypertensive men

Soccer training can significantly reduce blood pressure and improve aerobic fitness in hypertensive middle-aged men, researchers say.

17 Oct 2012

Men with childhood ADHD have multiple disadvantages throughout their lifetime

A new study conducted by researchers at the Child Study Center at NYU Langone Medical Center found men diagnosed as children with attention-deficit/hyperactivity disorder (ADHD) had significantly worse educational, occupational, economic and social outcomes in a 33-year follow-up study compared to men who were not diagnosed.

16 Oct 2012

GILZ protein encourages bone growth in mouse model

Georgia Health Sciences University researchers have developed a mouse that errs on the side of making bone rather than fat, which could eventually lead to better drugs to treat inflammatory diseases such as rheumatoid arthritis.

16 Oct 2012

Nighttime BP dipping abnormalities in young adults linked to later atherosclerosis

Young adults whose systolic blood pressure fails to dip sufficiently or overdips during nighttime may be at increased risk for coronary atherosclerosis later in life, research reveals.

15 Oct 2012

Rheumatoid arthritis treatment foiled by gum disease

Periodontal disease may reduce the efficacy of tumor necrosis factor inhibitor treatment in patients with rheumatoid arthritis, preliminary research suggests.

15 Oct 2012

Enrollment complete in Idera's IMO-3100 Phase 2 trial for psoriasis

Idera Pharmaceuticals today announced that it had completed patient enrollment in its randomized, double-blind, placebo-controlled Phase 2 trial of IMO-3100 in patients with moderate-to-severe plaque psoriasis. IMO-3100 is an antagonist of specific Toll-like Receptors (TLRs) that the Company is developing for the treatment of psoriasis and other autoimmune diseases.

15 Oct 2012

Regulatory B cells may provide effective treatment for severe autoimmune diseases

Reproducing a rare type of B cell in the laboratory and infusing it back into the body may provide an effective treatment for severe autoimmune diseases such as multiple sclerosis or rheumatoid arthritis, according to researchers at Duke University Medical Center.

15 Oct 2012

Database of drug-induced liver injury now available from NIH

A free source of evidence-based information for health care professionals and for researchers studying liver injury associated with prescription and over-the-counter drugs, herbals, and dietary supplements is now available from the National Institutes of Health. Researchers and health care professionals can use the LiverTox database to identify basic and clinical research questions to be answered and to chart optimal ways to diagnose and control drug-induced liver injury.

15 Oct 2012

Highlights of Mount Sinai research at Neuroscience 2012

Researchers from Mount Sinai School of Medicine are presenting important discoveries on the involvement of the immune system and dopamine cells in the onset of depression at Neuroscience 2012, the Society for Neuroscience's 42nd annual meeting on October 13 -17 in New Orleans, and are available for interviews.

15 Oct 2012

Genzyme announces key data from AUBAGIO Phase III trial on multiple sclerosis

Genzyme, a Sanofi company announced today that key data from the TOWER trial were presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS).

15 Oct 2012