Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Santarus commences SAN-300 Phase I clinical study to treat inflammatory diseases

Santarus, Inc., a specialty biopharmaceutical company, today announced that it has initiated a Phase I clinical study with SAN-300, its anti-VLA-1 antibody.

10 Mar 2011

ALR commits funding for new study to identify lupus susceptibility genes in multiple ethnicities

The Alliance for Lupus Research (ALR) – the world's largest private funder of lupus research – today announced funding of an important new study to identify lupus susceptibility genes in multiple ethnicities including African Americans, who are three times more likely than Caucasians to have the disease.

10 Mar 2011

Merck to present VICTRELIS phase III study data against HCV at EASL annual meeting

Merck, known as MSD outside of the United States and Canada, announced that several new data analyses from Phase III studies of VICTRELIS, its investigational oral hepatitis C protease inhibitor, will be presented at The International Liver CongressTM / 46th European Association for the Study of the Liver annual meeting.

9 Mar 2011

Three new research initiatives to study how design of neighbourhoods impact obesity

The Honourable Leona Aglukkaq, Minister of Health, today announced three new research initiatives studying how the design of neighbourhoods impact obesity. The studies were funded by the Canadian Institutes of Health Research and the Heart and Stroke Foundation of Canada.

9 Mar 2011

'Cross-talk' between two major biological pathways may hold a clue for chronic pain treatment

Researchers at the University of California, Davis have discovered a "cross-talk" between two major biological pathways that involve pain-research that may pave the way to new approaches to understanding and controlling chronic pain.

9 Mar 2011

Karolinska Institutet, LUMC coordinate largest European program on RA

Karolinska Institutet in Sweden and Leiden University Medical Center (LUMC) in the Netherlands will coordinate the largest European program so far, aimed at developing new therapies against Rheumatoid Arthritis (RA). The program, named Be The Cure (BTCure), is funded for the next 5 years by the Innovative Medicines Initiative (IMI), and will bring together academic rheumatology research and research in pharmaceutical companies in Europe.

9 Mar 2011

ADAM-12 gene can serve as treatment target for cancer, arthritis, cardiac hypertrophy

ADAM-12 is not only the name of a 1970's television police drama - it's also the gene that University of Missouri researchers believe could be an important element in the fight against cancer, arthritis, and cardiac hypertrophy, or thickening of the heart's walls.

9 Mar 2011

Treatment with sildenafil significantly reduces RP in patients with scleroderma

Researchers in Europe reported that treatment with modified-release sildenafil significantly reduced the frequency of attacks of Raynaud's phenomenon in patients with limited cutaneous systemic sclerosis, also known as scleroderma.

8 Mar 2011

Recent rituximab trial with TNF inhibitors reports no new safety risks in patients with RA

A recent trial of rituximab in combination with a tumor necrosis factor inhibitor and methotrexate in patients with active rheumatoid arthritis found the safety profile to be consistent with other RA trials with TNF inhibitors.

8 Mar 2011

Arthritis handle kitchen tool for RA sufferers

His design has earnt a spot on the first-round shortlist of one of the world's most prestigious design competitions - the Australian Design Award/James Dyson Award.

8 Mar 2011

New clinical trial to assess antiretroviral treatment in HIV-infected individuals based on CD4 counts

A major new clinical trial seeks to determine whether HIV-infected asymptomatic individuals have less risk of developing AIDS or other serious illness if they begin taking antiretrovirals sooner rather than later, based on their level of CD4+ T-cells.

8 Mar 2011

North Shore-LIJ launches new prenatal quality initiative

Having a child is a life event that is equal parts magic and fear. Will the baby be healthy? Will labor and delivery pose challenges? Are there ways to reduce the risk for adverse events? Hospital obstetrical units face these questions round-the-clock.

8 Mar 2011

New Lupus drug marching towards approval

A new drug for lupus from the Human Genome Sciences Inc is all set to get clearance in the US this week. If all goes through, this drug will offer patients the first approved treatment option in a half-century, setting the manufacturer up for huge sales.

7 Mar 2011

Study examines impact of clinical, basic biomedical research on future work, products, healthcare

Clinical research has greater societal impact over a 15-20 year timescale, while basic research has greater academic impact, according to a new study from RAND Europe and the Health Economics Research Group at Brunel University.

6 Mar 2011

Dr Russell Wallis, Reader and RCUK Academic Fellow to give Frank May Prize Lecture 2010

The Frank May Prize Lecture 2010, entitled 'Fishing for Complement: innate targeting of microbial pathogens', will be given by Dr Russell Wallis, Reader and RCUK Academic Fellow in the Department of Infection, Immunity and Inflammation, and Department of Biochemistry.

5 Mar 2011

Researchers use qMRI to confirm effect of CS treatment in patients with OA

A group of Canadian researchers led by Prof. Jean-Pierre Pelletier, Head of the Osteoarthritis Research Unit at the University of Montreal Hospital Research Centre, published a clinical trial in which they confirm, for the first time using quantitative Magnetic Resonance Imaging, the disease modifying effects of chondroitin sulphate, a symptomatic slow acting drug for osteoarthritis.

5 Mar 2011

Pfizer's ORAL Sync Phase 3 study of tofacitinib in moderate-to-severe RA meets primary endpoints

Pfizer Inc. today announced that the ORAL Sync Phase 3 study of tofacitinib, formerly known as tasocitinib, an investigational, novel, oral JAK inhibitor, being studied in moderate-to-severe rheumatoid arthritis, met its primary endpoints by showing statistically significant changes versus placebo in reducing signs and symptoms of RA, as measured by ACR20 response rates at six months; in improving physical function, as measured by mean change in HAQ DI at three months; and in reaching DAS28-4 <2.6 at six months.

5 Mar 2011

Scientist discovers new mechanism for regulation of gene expression

Dr. David Levin, Professor of Molecular & Cell Biology at Boston University Henry M. Goldman School of Dental Medicine and Professor of Microbiology at Boston University School of Medicine discovered recently a novel, evolutionarily conserved mechanism for the regulation of gene expression.

4 Mar 2011

Canadian nurses call for changes to health system

Canadian Nurses Association (CNA) president Judith Shamian and Nursing Association of New Brunswick (NANB) president Martha Vickers announced today that their organizations will join forces to press for changes to Canada's health system.

4 Mar 2011

Triptolide isolated from Chinese medicinal plant blocks gene control machinery in cells

Researchers at the Johns Hopkins School of Medicine have discovered that a natural product isolated from a traditional Chinese medicinal plant commonly known as thunder god vine, or lei gong teng, and used for hundreds of years to treat many conditions including rheumatoid arthritis works by blocking gene control machinery in the cell. The report, published as a cover story of the March issue of Nature Chemical Biology, suggests that the natural product could be a starting point for developing new anticancer drugs.

4 Mar 2011

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Santarus commences SAN-300 Phase I clinical study to treat inflammatory diseases

ALR commits funding for new study to identify lupus susceptibility genes in multiple ethnicities

Merck to present VICTRELIS phase III study data against HCV at EASL annual meeting

Three new research initiatives to study how design of neighbourhoods impact obesity

'Cross-talk' between two major biological pathways may hold a clue for chronic pain treatment

Karolinska Institutet, LUMC coordinate largest European program on RA

ADAM-12 gene can serve as treatment target for cancer, arthritis, cardiac hypertrophy

Treatment with sildenafil significantly reduces RP in patients with scleroderma

Recent rituximab trial with TNF inhibitors reports no new safety risks in patients with RA

Arthritis handle kitchen tool for RA sufferers

New clinical trial to assess antiretroviral treatment in HIV-infected individuals based on CD4 counts

North Shore-LIJ launches new prenatal quality initiative

New Lupus drug marching towards approval

Study examines impact of clinical, basic biomedical research on future work, products, healthcare

Dr Russell Wallis, Reader and RCUK Academic Fellow to give Frank May Prize Lecture 2010

Researchers use qMRI to confirm effect of CS treatment in patients with OA

Pfizer's ORAL Sync Phase 3 study of tofacitinib in moderate-to-severe RA meets primary endpoints

Scientist discovers new mechanism for regulation of gene expression

Canadian nurses call for changes to health system

Triptolide isolated from Chinese medicinal plant blocks gene control machinery in cells

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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